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• W4385289904 abstract "Mechanical ventilation (MV), although life-saving, is associated with chronic respiratory morbidity in both preterm and term born infants. New ventilation modes have been developed with the aim of minimising lung injury. These include invasive and non-invasive respiratory support strategies, techniques for less invasive surfactant administration (LISA) and closed-loop automated oxygen control (CLAC) systems. Increasingly, newborn infants with signs of respiratory distress are stabilised on continuous positive airway pressure (CPAP) and receive LISA. Early CPAP when compared to mechanical ventilation reduced the incidence of BPD and respiratory morbidity at 18 to 22 months corrected age. Nasal intermittent positive pressure ventilation reduced treatment failure rates compared to CPAP, but not bronchopulmonary dysplasia (BPD). LISA compared with intubation and surfactant delivery reduced BPD, but there is no evidence from randomised trials regarding long-term respiratory and neurodevelopmental outcomes. Synchronisation of positive pressure inflations with the infant's respiratory efforts used with volume targeting should be applied for infants requiring intubation as this strategy reduces BPD. A large RCT with long term follow up data demonstrated that prophylactic high frequency oscillatory ventilation (HFOV) improved respiratory and functional outcomes at school age, but those effects were not maintained after puberty. CLAC systems appear promising, but their effect on long term clinical outcomes has not yet been explored in randomised trials. Further studies are required to determine the role of newer ventilation modes such as neurally adjusted ventilator assist (NAVA). All such respiratory support strategies should be tested in randomised controlled trials powered to assess long-term outcomes." @default.
• W4385289904 created "2023-07-27" @default.
• W4385289904 creator A5031095057 @default.
• W4385289904 creator A5086324962 @default.
• W4385289904 creator A5089191522 @default.
• W4385289904 date "2023-07-26" @default.
• W4385289904 modified "2023-10-18" @default.
• W4385289904 title "Neonatal respiratory support strategies—short and long-term respiratory outcomes" @default.
• W4385289904 cites W1542182745 @default.
• W4385289904 cites W1736255626 @default.
• W4385289904 cites W1871048676 @default.
• W4385289904 cites W1901652242 @default.
• W4385289904 cites W1953559626 @default.
• W4385289904 cites W1966963224 @default.
• W4385289904 cites W1977934675 @default.
• W4385289904 cites W1981871561 @default.
• W4385289904 cites W1984253620 @default.
• W4385289904 cites W1986946410 @default.
• W4385289904 cites W1996609794 @default.
• W4385289904 cites W2000587826 @default.
• W4385289904 cites W2006964180 @default.
• W4385289904 cites W2006966513 @default.
• W4385289904 cites W2023252147 @default.
• W4385289904 cites W2045573333 @default.
• W4385289904 cites W2050896066 @default.
• W4385289904 cites W2053931185 @default.
• W4385289904 cites W2057539198 @default.
• W4385289904 cites W2070544248 @default.
• W4385289904 cites W2097384986 @default.
• W4385289904 cites W2098144198 @default.
• W4385289904 cites W2098446194 @default.
• W4385289904 cites W2107819902 @default.
• W4385289904 cites W2108296176 @default.
• W4385289904 cites W2109095408 @default.
• W4385289904 cites W2109276024 @default.
• W4385289904 cites W2117693102 @default.
• W4385289904 cites W2119320080 @default.
• W4385289904 cites W2121839606 @default.
• W4385289904 cites W2132937584 @default.
• W4385289904 cites W2133757976 @default.
• W4385289904 cites W2147147275 @default.
• W4385289904 cites W2157302622 @default.
• W4385289904 cites W2167422913 @default.
• W4385289904 cites W2168020955 @default.
• W4385289904 cites W2168444022 @default.
• W4385289904 cites W2195903441 @default.
• W4385289904 cites W2331371605 @default.
• W4385289904 cites W2339655924 @default.
• W4385289904 cites W2361954081 @default.
• W4385289904 cites W2397033595 @default.
• W4385289904 cites W2466586463 @default.
• W4385289904 cites W2507320064 @default.
• W4385289904 cites W2508331570 @default.
• W4385289904 cites W2518462576 @default.
• W4385289904 cites W2529911178 @default.
• W4385289904 cites W2567032659 @default.
• W4385289904 cites W2586419414 @default.
• W4385289904 cites W2662622221 @default.
• W4385289904 cites W2727324185 @default.
• W4385289904 cites W2734161394 @default.
• W4385289904 cites W2738190966 @default.
• W4385289904 cites W2765573602 @default.
• W4385289904 cites W2766025758 @default.
• W4385289904 cites W2769667260 @default.
• W4385289904 cites W2781931687 @default.
• W4385289904 cites W2791234992 @default.
• W4385289904 cites W2807027117 @default.
• W4385289904 cites W2829329511 @default.
• W4385289904 cites W2884930939 @default.
• W4385289904 cites W2888361447 @default.
• W4385289904 cites W2890096487 @default.
• W4385289904 cites W2898777580 @default.
• W4385289904 cites W2901316157 @default.
• W4385289904 cites W2902538200 @default.
• W4385289904 cites W2902902012 @default.
• W4385289904 cites W2909817999 @default.
• W4385289904 cites W2921374379 @default.
• W4385289904 cites W2932223499 @default.
• W4385289904 cites W2937916298 @default.
• W4385289904 cites W2960398430 @default.
• W4385289904 cites W2966684402 @default.
• W4385289904 cites W2967832570 @default.
• W4385289904 cites W2969018697 @default.
• W4385289904 cites W2970827569 @default.
• W4385289904 cites W2986032671 @default.
• W4385289904 cites W2990770667 @default.
• W4385289904 cites W3007144244 @default.
• W4385289904 cites W3011141288 @default.
• W4385289904 cites W3013196603 @default.
• W4385289904 cites W3047578841 @default.
• W4385289904 cites W3047722577 @default.
• W4385289904 cites W3048424735 @default.
• W4385289904 cites W3106402208 @default.
• W4385289904 cites W3130996486 @default.
• W4385289904 cites W3161404142 @default.
• W4385289904 cites W3161537182 @default.
• W4385289904 cites W3191208200 @default.
• W4385289904 cites W3206620706 @default.
• W4385289904 cites W3215857364 @default.
• W4385289904 cites W3216920922 @default.

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