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• W4385294562 abstract "We aimed to investigate the association of long-term dietary iron intake with the risk of nonfatal CVDs, myocardial infarction (MI), and stroke in Chinese populations with predominantly plant-based diets by sex.A total of 17,107 participants (8,569 men and 8,538 women) aged 18-80 years in the China Health and Nutrition Survey (CHNS) 1989-2015 were included. Dietary intake was assessed repeatedly by three consecutive 24-hour dietary recalls. Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).During a median follow-up of 11.1 years, the adjusted HRs (95% CIs) for nonfatal CVD risk across quintiles of total iron intake in men were 1.00, 0.65 (0.46-0.93), 0.54 (0.37-0.78), 0.66 (0.46-0.94), 0.69 (0.47-1.03), but no significant association in women. Similar associations were found for stroke risk, but not for MI risk. The dose-response curves for the association of total iron and nonheme iron intake with the risk of nonfatal CVDs and stroke followed a reverse J-shape only in men and similar reverse J-shaped association of heme iron intake with nonfatal CVD and stroke risk in both men and women (P-nonlinearity < 0.05).Moderate dietary iron intake may protect against nonfatal CVDs and stroke, especially in Chinese men consuming plant-based diets. Both quantity and quality of dietary iron intake should be considered in the prevention of nonfatal CVDs due to differences in dietary patterns among diverse populations.This prospective cohort study, using data from 8,569 men and 8,538 women who participated in the China Health and Nutrition Survey (CHNS) 1989-2015, suggests that moderate intake of dietary iron may protect against nonfatal cardiovascular diseases (CVDs) and stroke, especially in men consuming predominantly plant-based diets." @default.
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• W4385294562 date "2023-07-26" @default.
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• W4385294562 title "Long-term dietary iron intake and risk of nonfatal cardiovascular diseases in the China Health and Nutrition Survey" @default.
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• W4385294562 doi "https://doi.org/10.1093/eurjpc/zwad244" @default.
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