Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385295859> ?p ?o ?g. }
- W4385295859 abstract "ABSTRACT Appropriate responses to real or potential damaging stimuli to the body (nociception) are critical to an animal's short- and long-term survival. The initial goal of this study was to examine habituation of withdrawal reflexes (whole-body and local shortening) to repeated mechanical nociceptive stimuli (needle pokes) in the medicinal leech, Hirudo verbana, and assess whether injury altered habituation to these nociceptive stimuli. While repeated needle pokes did reduce shortening in H. verbana, a second set of behavior changes was observed. Specifically, animals began to evade subsequent stimuli by either hiding their posterior sucker underneath adjacent body segments or engaging in locomotion (crawling). Animals differed in terms of how quickly they adopted evasion behaviors during repeated stimulation, exhibiting a multi-modal distribution for early, intermediate and late evaders. Prior injury had a profound effect on this transition, decreasing the time frame in which animals began to carry out evasion and increasing the magnitude of these evasion behaviors (more locomotory evasion). The data indicate the presence in Hirudo of a complex and adaptive defensive arousal process to avoid noxious stimuli that is influenced by differences in internal states, prior experience with injury of the stimulated areas, and possibly learning-based processes." @default.
- W4385295859 created "2023-07-28" @default.
- W4385295859 creator A5023060535 @default.
- W4385295859 creator A5079719495 @default.
- W4385295859 creator A5091260987 @default.
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- W4385295859 date "2023-08-15" @default.
- W4385295859 modified "2023-09-27" @default.
- W4385295859 title "Repetitive nociceptive stimulation elicits complex behavioral changes in <i>Hirudo</i>: evidence of arousal and motivational adaptations" @default.
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- W4385295859 doi "https://doi.org/10.1242/jeb.245895" @default.