Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385302329> ?p ?o ?g. }
- W4385302329 abstract "The neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are simple markers of systemic inflammatory responses. It has been previously suggested that they can predict COVID-19 severity. Age and frailty may also influence their values. This study aimed to evaluate the impact of COVID-19 severity versus age and frailty on NLR and PLR values. This was a retrospective, observational two cohorts' comparative study. The first cohort is comprised of patents positive for SARS-CoV-2, with mild or asymptomatic disease, admitted to designated COVID-19 departments in a large geriatric medical center (GMC). The second included patients with COVID-19 admitted to designated COVID-19 departments in a large general hospital for symptomatic disease from March 2020 to March 2021. We compared baseline characteristics including comorbidities and chronic medications, disease symptoms, laboratory tests and compared the NLR and PLR between the two groups. The 177 patients admitted to the COVID-designated department in the GMC were over three decades older than the 289 COVID-19 patients admitted to the general hospital care (HC). They had substantially more comorbidities and chronic medications. All common disease symptoms were significantly more common in the HC group. Almost two thirds of the GMC patients remained asymptomatic compared to 2.1% in the HC group. Inflammatory markers, such as CRP and LDH, were significantly higher in the HC group. The NLR and PLR were both significantly higher in the GMC cohort comprised of older frailer patients with milder disease. NLR and PLR seem to be affected more by age and frailty than COVID-19 severity." @default.
- W4385302329 created "2023-07-28" @default.
- W4385302329 creator A5011820597 @default.
- W4385302329 creator A5040267017 @default.
- W4385302329 creator A5062348234 @default.
- W4385302329 creator A5072565963 @default.
- W4385302329 creator A5076314642 @default.
- W4385302329 creator A5092551989 @default.
- W4385302329 creator A5092551990 @default.
- W4385302329 creator A5092551991 @default.
- W4385302329 creator A5092551992 @default.
- W4385302329 date "2023-07-27" @default.
- W4385302329 modified "2023-10-14" @default.
- W4385302329 title "Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio, are they markers of COVID-19 severity or old age and frailty? A comparison of two distinct cohorts" @default.
- W4385302329 cites W1967974729 @default.
- W4385302329 cites W2147212677 @default.
- W4385302329 cites W2164186760 @default.
- W4385302329 cites W2512237930 @default.
- W4385302329 cites W2593316394 @default.
- W4385302329 cites W2954693483 @default.
- W4385302329 cites W2956736072 @default.
- W4385302329 cites W2985108763 @default.
- W4385302329 cites W3011664785 @default.
- W4385302329 cites W3014695022 @default.
- W4385302329 cites W3016124709 @default.
- W4385302329 cites W3016987930 @default.
- W4385302329 cites W3020646040 @default.
- W4385302329 cites W3038265715 @default.
- W4385302329 cites W3043040397 @default.
- W4385302329 cites W3046897928 @default.
- W4385302329 cites W3084456072 @default.
- W4385302329 cites W3092136311 @default.
- W4385302329 cites W3092837137 @default.
- W4385302329 cites W3096391727 @default.
- W4385302329 cites W3108574318 @default.
- W4385302329 cites W3111018862 @default.
- W4385302329 cites W3112395022 @default.
- W4385302329 cites W3120714071 @default.
- W4385302329 cites W3126379194 @default.
- W4385302329 cites W3132340173 @default.
- W4385302329 cites W3147784348 @default.
- W4385302329 cites W3152534948 @default.
- W4385302329 cites W3176127339 @default.
- W4385302329 cites W3207729141 @default.
- W4385302329 cites W3212264534 @default.
- W4385302329 cites W4200559856 @default.
- W4385302329 cites W4205089143 @default.
- W4385302329 cites W4205862259 @default.
- W4385302329 cites W4206176725 @default.
- W4385302329 cites W4210279475 @default.
- W4385302329 cites W4221067521 @default.
- W4385302329 cites W4223481163 @default.
- W4385302329 cites W4289637910 @default.
- W4385302329 cites W4296949333 @default.
- W4385302329 cites W4298396068 @default.
- W4385302329 cites W4308121874 @default.
- W4385302329 cites W4308635942 @default.
- W4385302329 doi "https://doi.org/10.3389/fmed.2023.1222692" @default.
- W4385302329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37575993" @default.
- W4385302329 hasPublicationYear "2023" @default.
- W4385302329 type Work @default.
- W4385302329 citedByCount "0" @default.
- W4385302329 crossrefType "journal-article" @default.
- W4385302329 hasAuthorship W4385302329A5011820597 @default.
- W4385302329 hasAuthorship W4385302329A5040267017 @default.
- W4385302329 hasAuthorship W4385302329A5062348234 @default.
- W4385302329 hasAuthorship W4385302329A5072565963 @default.
- W4385302329 hasAuthorship W4385302329A5076314642 @default.
- W4385302329 hasAuthorship W4385302329A5092551989 @default.
- W4385302329 hasAuthorship W4385302329A5092551990 @default.
- W4385302329 hasAuthorship W4385302329A5092551991 @default.
- W4385302329 hasAuthorship W4385302329A5092551992 @default.
- W4385302329 hasBestOaLocation W43853023291 @default.
- W4385302329 hasConcept C126322002 @default.
- W4385302329 hasConcept C167135981 @default.
- W4385302329 hasConcept C201903717 @default.
- W4385302329 hasConcept C2777761686 @default.
- W4385302329 hasConcept C2777910003 @default.
- W4385302329 hasConcept C2778963024 @default.
- W4385302329 hasConcept C2779134260 @default.
- W4385302329 hasConcept C30036603 @default.
- W4385302329 hasConcept C3008058167 @default.
- W4385302329 hasConcept C524204448 @default.
- W4385302329 hasConcept C71924100 @default.
- W4385302329 hasConcept C72563966 @default.
- W4385302329 hasConceptScore W4385302329C126322002 @default.
- W4385302329 hasConceptScore W4385302329C167135981 @default.
- W4385302329 hasConceptScore W4385302329C201903717 @default.
- W4385302329 hasConceptScore W4385302329C2777761686 @default.
- W4385302329 hasConceptScore W4385302329C2777910003 @default.
- W4385302329 hasConceptScore W4385302329C2778963024 @default.
- W4385302329 hasConceptScore W4385302329C2779134260 @default.
- W4385302329 hasConceptScore W4385302329C30036603 @default.
- W4385302329 hasConceptScore W4385302329C3008058167 @default.
- W4385302329 hasConceptScore W4385302329C524204448 @default.
- W4385302329 hasConceptScore W4385302329C71924100 @default.
- W4385302329 hasConceptScore W4385302329C72563966 @default.
- W4385302329 hasLocation W43853023291 @default.
- W4385302329 hasLocation W43853023292 @default.
- W4385302329 hasLocation W43853023293 @default.