FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385306845> ?p ?o ?g. }

• W4385306845 abstract "<h3>Aim</h3> Presenting features and current status of children who presented with acute non-A-E hepatitis in a district general hospital <h3>Method</h3> We looked at all cases of children (<16 yrs) who presented with acute hepatitis during March & April 2022. Presenting symptoms, clinical findings, level of transaminitis, presence of coagulopathy were noted. Investigations were based on the guidance issued by the RCPCH on acute non-A-E hepatitis during the same time period. Patients were discussed with the tertiary centre. After discharge patients were assessed monthly for the first 6 months and then 2 monthly where possible in the outpatient clinics. <h3>Results</h3> 9 patients presented with transaminitis during a period which coincided with a spike in acute non-A-E hepatitis paediatric cases nationally. 77% of patients were females. The ages of patients ranged 2.5 to 6 years corroborating what has been observed nationally. .All patients had some gastrointestinal symptoms (anorexia, vomiting, loose stools or abdominal pain). 44% abdominal pain, 44% loose stools and 22% vomiting. 11% had lethargy and 55% were clinically jaundiced. 44% had acute liver failure either at presentation or during their admission. Two patients were readmitted after their initial admission episode because of worsening transaminitis trend. Surprisingly none had pruritus. Acute non-A-E hepatitis investigative work up as per RCPCH guidance was negative in all cases except finding the presence of Adenovirus & Enterovirus. 66% (6 patients) had PCR positive for Adenovirus and 11% (1 patient) for Enterovirus. On presentation 66% had hyperbilirubinemia and 33% presented coagulopathy. 66% were treated with Vitamin K but only 55% were managed with Urso-deoxycholic acid and fat-soluble vitamins. Only two patients needed transfer to the local tertiary hospital, rest were effectively managed locally <h3>Conclusion</h3> Nationally there was a spike in children presenting with acute hepatitis. We had similar cases. Although only 66% cases have their transaminitis completely resolved, all children are asymptomatic and clinically well at the last clinical review. We hope our data supports other hospital findings and adds to the national database for future surveillance." @default.
• W4385306845 created "2023-07-28" @default.
• W4385306845 creator A5005948108 @default.
• W4385306845 date "2023-07-01" @default.
• W4385306845 modified "2023-09-26" @default.
• W4385306845 title "OC58 Single centre experience for children who presented with acute non-A-E hepatitis in March & April 2022: 10 months on" @default.
• W4385306845 doi "https://doi.org/10.1136/flgastro-2023-bspghan.57" @default.
• W4385306845 hasPublicationYear "2023" @default.
• W4385306845 type Work @default.
• W4385306845 citedByCount "0" @default.
• W4385306845 crossrefType "proceedings-article" @default.
• W4385306845 hasAuthorship W4385306845A5005948108 @default.
• W4385306845 hasConcept C126322002 @default.
• W4385306845 hasConcept C187212893 @default.
• W4385306845 hasConcept C203014093 @default.
• W4385306845 hasConcept C2522874641 @default.
• W4385306845 hasConcept C2775876817 @default.
• W4385306845 hasConcept C2776029263 @default.
• W4385306845 hasConcept C2777260799 @default.
• W4385306845 hasConcept C2777888124 @default.
• W4385306845 hasConcept C2778456037 @default.
• W4385306845 hasConcept C2778654693 @default.
• W4385306845 hasConcept C2779936836 @default.
• W4385306845 hasConcept C2780852908 @default.
• W4385306845 hasConcept C2780955771 @default.
• W4385306845 hasConcept C3018886096 @default.
• W4385306845 hasConcept C3020110884 @default.
• W4385306845 hasConcept C71924100 @default.
• W4385306845 hasConceptScore W4385306845C126322002 @default.
• W4385306845 hasConceptScore W4385306845C187212893 @default.
• W4385306845 hasConceptScore W4385306845C203014093 @default.
• W4385306845 hasConceptScore W4385306845C2522874641 @default.
• W4385306845 hasConceptScore W4385306845C2775876817 @default.
• W4385306845 hasConceptScore W4385306845C2776029263 @default.
• W4385306845 hasConceptScore W4385306845C2777260799 @default.
• W4385306845 hasConceptScore W4385306845C2777888124 @default.
• W4385306845 hasConceptScore W4385306845C2778456037 @default.
• W4385306845 hasConceptScore W4385306845C2778654693 @default.
• W4385306845 hasConceptScore W4385306845C2779936836 @default.
• W4385306845 hasConceptScore W4385306845C2780852908 @default.
• W4385306845 hasConceptScore W4385306845C2780955771 @default.
• W4385306845 hasConceptScore W4385306845C3018886096 @default.
• W4385306845 hasConceptScore W4385306845C3020110884 @default.
• W4385306845 hasConceptScore W4385306845C71924100 @default.
• W4385306845 hasLocation W43853068451 @default.
• W4385306845 hasOpenAccess W4385306845 @default.
• W4385306845 hasPrimaryLocation W43853068451 @default.
• W4385306845 hasRelatedWork W1995338601 @default.
• W4385306845 hasRelatedWork W2004573020 @default.
• W4385306845 hasRelatedWork W2319910297 @default.
• W4385306845 hasRelatedWork W2410135030 @default.
• W4385306845 hasRelatedWork W2415186157 @default.
• W4385306845 hasRelatedWork W2614656420 @default.
• W4385306845 hasRelatedWork W2900302416 @default.
• W4385306845 hasRelatedWork W2910430287 @default.
• W4385306845 hasRelatedWork W2944996884 @default.
• W4385306845 hasRelatedWork W3124155057 @default.
• W4385306845 isParatext "false" @default.
• W4385306845 isRetracted "false" @default.
• W4385306845 workType "article" @default.