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- W4385322920 abstract "Abstract Cardiac function and vascular hemodynamics in the adult are primarily regulated through neural control mechanisms. However, functional hemodynamic control during primary cardiac development occurs prior to central nervous system development [Pappano 77]. Studies in our laboratory have shown that peak volumetric blood flow rate is amplitude modulated in the preinnervated embryo [Kempski 93]. This peak amplitude variability suggests an early mechanism for hemodynamic regulation which supplements beat-to-beat regulation via Frank-Starling mechanisms. We speculate that changes in vascular flow impedance may be the mechanism of hemodynamic regulation prior to the advent of neural control [Kempski 93]. We hypothesize that these changes can be modeled using three-element Windkessel analogs of cardiac afterload (Fig. 1)." @default.
- W4385322920 created "2023-07-28" @default.
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- W4385322920 date "1996-11-17" @default.
- W4385322920 modified "2023-09-23" @default.
- W4385322920 title "Windkessel Modeling of Cardiac Afterload in the Stage 21 and 24 Chick Embryo" @default.
- W4385322920 doi "https://doi.org/10.1115/imece1996-1182" @default.
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