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• W4385325317 abstract "Chronic pain remains poorly managed. The integration of innovative immersive technologies (i.e., virtual reality (VR)) with recent neuroscience-based principles that position the brain as the key organ of chronic pain may provide a more effective pain treatment than traditional behavioral therapies. By targeting cognitive and affective processes that maintain pain and potentially directly changing neurobiological circuits associated with pain chronification and amplification, VR-based pain treatment has the potential for significant and long-lasting pain relief. We tested the effectiveness of a novel VR neuroscience-based therapy (VRNT) to improve pain-related outcomes in n = 31 participants with chronic back pain, evaluated against usual care (n = 30) in a 2-arm randomized clinical trial ( NCT04468074) . We also conducted pre- and post-treatment MRI to test whether VRNT affects brain networks previously linked to chronic pain and treatment effects. Compared to the control condition, VRNT led to significantly reduced pain intensity (g = 0.63) and pain interference (g = 0.84) at post-treatment vs. pre-treatment, with effects persisting at 2-week follow-up. The improvements were partially mediated by reduced kinesiophobia and pain catastrophizing. Several secondary clinical outcomes were also improved, including disability, quality of life, sleep, and fatigue. In addition, VRNT was associated with modest increases in functional connectivity of the somatomotor and default mode networks and decreased white matter fractional anisotropy in the corpus callosum adjacent to anterior cingula, relative to the control condition. This, VRNT showed preliminary efficacy in significantly reducing pain and improving overall functioning, possibly via changes in somatosensory and prefrontal brain networks." @default.
• W4385325317 created "2023-07-28" @default.
• W4385325317 creator A5006154621 @default.
• W4385325317 creator A5008650128 @default.
• W4385325317 creator A5020419303 @default.
• W4385325317 creator A5041065949 @default.
• W4385325317 creator A5073436407 @default.
• W4385325317 date "2023-07-27" @default.
• W4385325317 modified "2023-09-23" @default.
• W4385325317 title "The Effects of Virtual Reality Neuroscience-based Therapy on Clinical and Neuroimaging Outcomes in Patients with Chronic Back Pain: A Randomized Clinical Trial" @default.
• W4385325317 cites W1664843084 @default.
• W4385325317 cites W1948588766 @default.
• W4385325317 cites W1962885651 @default.
• W4385325317 cites W1975954553 @default.
• W4385325317 cites W1979233603 @default.
• W4385325317 cites W1997501248 @default.
• W4385325317 cites W1997576702 @default.
• W4385325317 cites W1999460576 @default.
• W4385325317 cites W2001951871 @default.
• W4385325317 cites W2029985169 @default.
• W4385325317 cites W2030430403 @default.
• W4385325317 cites W2034120147 @default.
• W4385325317 cites W2041627694 @default.
• W4385325317 cites W2045895137 @default.
• W4385325317 cites W2046504031 @default.
• W4385325317 cites W2049423401 @default.
• W4385325317 cites W2051649556 @default.
• W4385325317 cites W2058184618 @default.
• W4385325317 cites W2060360760 @default.
• W4385325317 cites W2063542227 @default.
• W4385325317 cites W2081653089 @default.
• W4385325317 cites W2082317966 @default.
• W4385325317 cites W2086551541 @default.
• W4385325317 cites W2100103888 @default.
• W4385325317 cites W2102747343 @default.
• W4385325317 cites W2113619522 @default.
• W4385325317 cites W2116978236 @default.
• W4385325317 cites W2121531670 @default.
• W4385325317 cites W2142829723 @default.
• W4385325317 cites W2149421654 @default.
• W4385325317 cites W2149444223 @default.
• W4385325317 cites W2150667092 @default.
• W4385325317 cites W2153661274 @default.
• W4385325317 cites W2159936035 @default.
• W4385325317 cites W2166182245 @default.
• W4385325317 cites W2172151487 @default.
• W4385325317 cites W2172200578 @default.
• W4385325317 cites W2175760214 @default.
• W4385325317 cites W2190112317 @default.
• W4385325317 cites W2304035054 @default.
• W4385325317 cites W2509938835 @default.
• W4385325317 cites W2511511558 @default.
• W4385325317 cites W2515706020 @default.
• W4385325317 cites W2521208344 @default.
• W4385325317 cites W2606016892 @default.
• W4385325317 cites W2742876406 @default.
• W4385325317 cites W2743976663 @default.
• W4385325317 cites W2778676578 @default.
• W4385325317 cites W2808831618 @default.
• W4385325317 cites W2883632486 @default.
• W4385325317 cites W2898582579 @default.
• W4385325317 cites W2901480911 @default.
• W4385325317 cites W2902670270 @default.
• W4385325317 cites W2919427425 @default.
• W4385325317 cites W2920111216 @default.
• W4385325317 cites W2951583631 @default.
• W4385325317 cites W2967545880 @default.
• W4385325317 cites W2969709992 @default.
• W4385325317 cites W2970824749 @default.
• W4385325317 cites W2991386074 @default.
• W4385325317 cites W3020626154 @default.
• W4385325317 cites W3023925850 @default.
• W4385325317 cites W3029670753 @default.
• W4385325317 cites W3033418019 @default.
• W4385325317 cites W3036589033 @default.
• W4385325317 cites W3082091395 @default.
• W4385325317 cites W3083038797 @default.
• W4385325317 cites W3101967757 @default.
• W4385325317 cites W3107990120 @default.
• W4385325317 cites W3111672553 @default.
• W4385325317 cites W3111897338 @default.
• W4385325317 cites W3119643745 @default.
• W4385325317 cites W3134194514 @default.
• W4385325317 cites W3152652132 @default.
• W4385325317 cites W3154966010 @default.
• W4385325317 cites W3160776804 @default.
• W4385325317 cites W3174100758 @default.
• W4385325317 cites W3194956376 @default.
• W4385325317 cites W3196703650 @default.
• W4385325317 cites W3200053086 @default.
• W4385325317 cites W3204387157 @default.
• W4385325317 cites W4200019418 @default.
• W4385325317 cites W4223531447 @default.
• W4385325317 cites W4229053071 @default.
• W4385325317 cites W4241614669 @default.
• W4385325317 cites W4249479234 @default.
• W4385325317 cites W4287835165 @default.
• W4385325317 cites W4291012209 @default.
• W4385325317 cites W4310777997 @default.
• W4385325317 cites W4366748040 @default.

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