Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385331571> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W4385331571 endingPage "e34441" @default.
- W4385331571 startingPage "e34441" @default.
- W4385331571 abstract "In this study, we explored the prognostic risk factors of elderly patients (≥65 years old) with lymph node-negative esophageal cancer (EC) and established a nomogram to evaluate the cancer-specific survival of patients. The surveillance, epidemiology, and end results database was used to collect data on patients diagnosed with EC. Univariate and multivariate Cox analyses were used to determine independent prognostic factors, and the nomogram for predicting cancer-specific survival of EC patients was constructed based on the independent prognostic factors obtained from the multivariate Cox analysis. To evaluate the predictive ability of the nomogram, calibration curves, concordance index (C-index), receiver operating characteristic curves, and decision curve analysis were conducted. Kaplan-Meier method was used to analyze the long-term outcomes of EC patients with different risk stratifications. A total of 3050 cases with lymph node-negative EC were randomized into the training cohort (1525) and the validation cohort (1525). Cancer-specific mortality at 1, 3, and 5 years in the entire cohort was 30.7%, 41.8%, and 59.2%, respectively. In multivariate Cox analysis, age (P < .001), marital status (P < .001), tumor size (P < .001), Tumor-node-metastasis stage (P < .001), chemotherapy (P = .011), radiotherapy (P < .001), and surgery (P < .001) were independent prognostic factors. The C-index for the training cohort was 0.740 (95% confidence interval [CI]: 0.722-0.758), and the C-index for the validation cohort was 0.738 (95% CI: 0.722-0.754). The calibration curve demonstrated the great calibration ability of the nomogram. Based on the area under the receiver operating characteristic curve, the nomogram demonstrated a higher sensitivity than the tumor-node-metastasis stage. Decision curve analysis showed the good clinical utility of the nomogram. The risk stratification system was established using the Kaplan-Meier curve and verified by the log-rank test (P < .001). The nomogram and risk stratification system can improve the accuracy of prediction to help clinicians identify high-risk patients and make treatment decisions." @default.
- W4385331571 created "2023-07-29" @default.
- W4385331571 creator A5029837334 @default.
- W4385331571 creator A5038449030 @default.
- W4385331571 creator A5042937865 @default.
- W4385331571 creator A5053343934 @default.
- W4385331571 creator A5053789094 @default.
- W4385331571 creator A5064604171 @default.
- W4385331571 date "2023-07-28" @default.
- W4385331571 modified "2023-10-16" @default.
- W4385331571 title "Development and validation of a prognostic nomogram for predicting cancer-specific survival in lymph node-negative elderly esophageal cancer patients: A SEER-based study" @default.
- W4385331571 cites W2178359734 @default.
- W4385331571 cites W2604999780 @default.
- W4385331571 cites W2800074290 @default.
- W4385331571 cites W2942659018 @default.
- W4385331571 cites W2969892844 @default.
- W4385331571 cites W2982110746 @default.
- W4385331571 cites W2997238693 @default.
- W4385331571 cites W3013383549 @default.
- W4385331571 cites W3015794034 @default.
- W4385331571 cites W3047577647 @default.
- W4385331571 cites W3122971006 @default.
- W4385331571 cites W3128646645 @default.
- W4385331571 cites W3167595303 @default.
- W4385331571 cites W3174542016 @default.
- W4385331571 cites W3182961196 @default.
- W4385331571 cites W3203714326 @default.
- W4385331571 cites W3206653588 @default.
- W4385331571 cites W3211488171 @default.
- W4385331571 cites W4200379385 @default.
- W4385331571 cites W4200584507 @default.
- W4385331571 cites W4210244634 @default.
- W4385331571 cites W4225821816 @default.
- W4385331571 doi "https://doi.org/10.1097/md.0000000000034441" @default.
- W4385331571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37505134" @default.
- W4385331571 hasPublicationYear "2023" @default.
- W4385331571 type Work @default.
- W4385331571 citedByCount "0" @default.
- W4385331571 crossrefType "journal-article" @default.
- W4385331571 hasAuthorship W4385331571A5029837334 @default.
- W4385331571 hasAuthorship W4385331571A5038449030 @default.
- W4385331571 hasAuthorship W4385331571A5042937865 @default.
- W4385331571 hasAuthorship W4385331571A5053343934 @default.
- W4385331571 hasAuthorship W4385331571A5053789094 @default.
- W4385331571 hasAuthorship W4385331571A5064604171 @default.
- W4385331571 hasBestOaLocation W43853315711 @default.
- W4385331571 hasConcept C10515644 @default.
- W4385331571 hasConcept C121608353 @default.
- W4385331571 hasConcept C126322002 @default.
- W4385331571 hasConcept C143998085 @default.
- W4385331571 hasConcept C160798450 @default.
- W4385331571 hasConcept C2779742542 @default.
- W4385331571 hasConcept C2780849966 @default.
- W4385331571 hasConcept C34626388 @default.
- W4385331571 hasConcept C38180746 @default.
- W4385331571 hasConcept C44249647 @default.
- W4385331571 hasConcept C50382708 @default.
- W4385331571 hasConcept C58471807 @default.
- W4385331571 hasConcept C71924100 @default.
- W4385331571 hasConcept C72563966 @default.
- W4385331571 hasConceptScore W4385331571C10515644 @default.
- W4385331571 hasConceptScore W4385331571C121608353 @default.
- W4385331571 hasConceptScore W4385331571C126322002 @default.
- W4385331571 hasConceptScore W4385331571C143998085 @default.
- W4385331571 hasConceptScore W4385331571C160798450 @default.
- W4385331571 hasConceptScore W4385331571C2779742542 @default.
- W4385331571 hasConceptScore W4385331571C2780849966 @default.
- W4385331571 hasConceptScore W4385331571C34626388 @default.
- W4385331571 hasConceptScore W4385331571C38180746 @default.
- W4385331571 hasConceptScore W4385331571C44249647 @default.
- W4385331571 hasConceptScore W4385331571C50382708 @default.
- W4385331571 hasConceptScore W4385331571C58471807 @default.
- W4385331571 hasConceptScore W4385331571C71924100 @default.
- W4385331571 hasConceptScore W4385331571C72563966 @default.
- W4385331571 hasIssue "30" @default.
- W4385331571 hasLocation W43853315711 @default.
- W4385331571 hasLocation W43853315712 @default.
- W4385331571 hasOpenAccess W4385331571 @default.
- W4385331571 hasPrimaryLocation W43853315711 @default.
- W4385331571 hasRelatedWork W1970018641 @default.
- W4385331571 hasRelatedWork W1987682868 @default.
- W4385331571 hasRelatedWork W1993821226 @default.
- W4385331571 hasRelatedWork W2004029742 @default.
- W4385331571 hasRelatedWork W2063908487 @default.
- W4385331571 hasRelatedWork W2089138782 @default.
- W4385331571 hasRelatedWork W2183151932 @default.
- W4385331571 hasRelatedWork W2806270659 @default.
- W4385331571 hasRelatedWork W4226494765 @default.
- W4385331571 hasRelatedWork W4233588653 @default.
- W4385331571 hasVolume "102" @default.
- W4385331571 isParatext "false" @default.
- W4385331571 isRetracted "false" @default.
- W4385331571 workType "article" @default.