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- W4385332304 abstract "Aim: Adverse effects should be questioned in outpatient clinics during routine visits. However, physicians have not yet had a questionnaire in Turkish for patients who take antiseizure medications (ASMs). The Liverpool Adverse Drug Events Profile “LAEP” was created to follow up on possible adverse effects of ASMs in different languages. This study aimed to assess the reliability and validity of LAEP for the Turkish-speaking population. Method: First, permission was requested from the authors of the original questionnaire. After that, English-Turkish and re-translations were made by two independent people, respectively. Finally, the questionnaire was administered to 10 people as a pilot study, and the final version was decided. Patients who were followed up at the epilepsy outpatient clinic of xxx Hospital and who had not changed antiseizure medications dosage for at least 3 months were included in the study. Cronbach's α and intraclass correlation coefficient (ICC) coefficients were calculated for internal consistency. A consistency study was performed by applying the scale to the same patient group with an interval of 2 weeks. Confirmatory factor analysis was performed for validity analyses using the questionnaire, which was divided into three subdimensions, neurologic, psychiatric, and other system adverse effects. Results: Thirty-seven [male: 16 (43.2%) and female: 21 (56.8%)] patients were included for test-retest analysis. Consistency measurements (ICCs) were performed, and high correlations of ICC >0.70 were obtained for all items. The questionnaire was administered to 168 [male: 64 (38.1%) and female: 104 (61.9%)] patients for validity by factor analysis and reliability by Cronbach's α correlation. Three dimensions were obtained in factor analysis, classified as nervous system-related, psychiatric-related, and other system-related. The Cronbach α values were found as 0.804, 0.828, and 0.484, respectively. Conclusion: The LAEP-TR scale can be used in outpatient clinics on patients who use ASMs." @default.
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- W4385332304 date "2023-01-01" @default.
- W4385332304 modified "2023-09-25" @default.
- W4385332304 title "The Liverpool Adverse Drug Events Profile (LAEP)" @default.
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- W4385332304 doi "https://doi.org/10.4103/nsn.nsn_83_23" @default.
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