Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385345757> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4385345757 endingPage "231" @default.
- W4385345757 startingPage "227" @default.
- W4385345757 abstract "Previously, we reported that the addition of duration to the Acute Kidney Injury Network (AKIN) definition of acute kidney injury (AKI) is a marker for more severe kidney injury and predicts long-term mortality. We aimed to evaluate an example of the utility of adding AKI duration to the AKIN definition by comparing the historical use of aprotinin with Amicar. In a single-center observational study, we followed 4987 consecutive patients undergoing cardiac surgery between 2002 and 2007 for postsurgery AKI. Patients with a history of hemodialysis were excluded. Duration of AKI was calculated by the number of days AKI was present as defined by a ≥0.3 (mg/dL) or a ≥50% increase in serum creatinine from baseline or new onset of acute dialysis. Kaplan-Meier and Cox’s proportional hazard modeling was conducted to evaluate 5-year mortality. Fifty-three percent of patients received Amicar (n = 2333) and 47% received high-dose aprotinin (n = 2093). Patients receiving aprotinin had evidence of more advanced disease and comorbidity and were more likely to develop AKI and have longer durations of AKI than Amicar ( p < .001): 7.0 ± 11.5 vs. 3.8 ± 6.0 days ( p < .001). Nearest-neighbor propensity matching demonstrated aprotinin had significantly worse 5-year mortality compared with Amicar (relative risk [RR] = 2.09, 95% confidence interval [CI] = 1.65–2.65). AKI duration added to the AKIN definition of AKI may provide the necessary sensitivity and specificity for evaluating renal outcomes in clinical trials." @default.
- W4385345757 created "2023-07-29" @default.
- W4385345757 creator A5024249077 @default.
- W4385345757 creator A5038940068 @default.
- W4385345757 creator A5074676816 @default.
- W4385345757 creator A5090634300 @default.
- W4385345757 date "2011-12-01" @default.
- W4385345757 modified "2023-09-23" @default.
- W4385345757 title "The Prognostic Value of Using the Duration of Acute Kidney Injury in Cardiac Surgery: An Example Using Two Antifibrinolytics" @default.
- W4385345757 cites W1967300023 @default.
- W4385345757 cites W1995205047 @default.
- W4385345757 cites W2033623167 @default.
- W4385345757 cites W2036454015 @default.
- W4385345757 cites W2060130484 @default.
- W4385345757 cites W2142945743 @default.
- W4385345757 cites W2144000717 @default.
- W4385345757 cites W2163972304 @default.
- W4385345757 doi "https://doi.org/10.1051/ject/201143227" @default.
- W4385345757 hasPublicationYear "2011" @default.
- W4385345757 type Work @default.
- W4385345757 citedByCount "0" @default.
- W4385345757 crossrefType "journal-article" @default.
- W4385345757 hasAuthorship W4385345757A5024249077 @default.
- W4385345757 hasAuthorship W4385345757A5038940068 @default.
- W4385345757 hasAuthorship W4385345757A5074676816 @default.
- W4385345757 hasAuthorship W4385345757A5090634300 @default.
- W4385345757 hasBestOaLocation W43853457571 @default.
- W4385345757 hasConcept C126322002 @default.
- W4385345757 hasConcept C141071460 @default.
- W4385345757 hasConcept C17923572 @default.
- W4385345757 hasConcept C207103383 @default.
- W4385345757 hasConcept C2778063415 @default.
- W4385345757 hasConcept C2778653478 @default.
- W4385345757 hasConcept C2779978075 @default.
- W4385345757 hasConcept C2780306776 @default.
- W4385345757 hasConcept C2780472472 @default.
- W4385345757 hasConcept C2780799893 @default.
- W4385345757 hasConcept C44249647 @default.
- W4385345757 hasConcept C50382708 @default.
- W4385345757 hasConcept C71924100 @default.
- W4385345757 hasConceptScore W4385345757C126322002 @default.
- W4385345757 hasConceptScore W4385345757C141071460 @default.
- W4385345757 hasConceptScore W4385345757C17923572 @default.
- W4385345757 hasConceptScore W4385345757C207103383 @default.
- W4385345757 hasConceptScore W4385345757C2778063415 @default.
- W4385345757 hasConceptScore W4385345757C2778653478 @default.
- W4385345757 hasConceptScore W4385345757C2779978075 @default.
- W4385345757 hasConceptScore W4385345757C2780306776 @default.
- W4385345757 hasConceptScore W4385345757C2780472472 @default.
- W4385345757 hasConceptScore W4385345757C2780799893 @default.
- W4385345757 hasConceptScore W4385345757C44249647 @default.
- W4385345757 hasConceptScore W4385345757C50382708 @default.
- W4385345757 hasConceptScore W4385345757C71924100 @default.
- W4385345757 hasIssue "4" @default.
- W4385345757 hasLocation W43853457571 @default.
- W4385345757 hasOpenAccess W4385345757 @default.
- W4385345757 hasPrimaryLocation W43853457571 @default.
- W4385345757 hasRelatedWork W113810927 @default.
- W4385345757 hasRelatedWork W1972357283 @default.
- W4385345757 hasRelatedWork W1998873451 @default.
- W4385345757 hasRelatedWork W2013507026 @default.
- W4385345757 hasRelatedWork W2118215538 @default.
- W4385345757 hasRelatedWork W2119154902 @default.
- W4385345757 hasRelatedWork W2240094448 @default.
- W4385345757 hasRelatedWork W2800272729 @default.
- W4385345757 hasRelatedWork W3051076900 @default.
- W4385345757 hasRelatedWork W3159983169 @default.
- W4385345757 hasVolume "43" @default.
- W4385345757 isParatext "false" @default.
- W4385345757 isRetracted "false" @default.
- W4385345757 workType "article" @default.