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• W4385348575 abstract "Colorectal cancer (CRC) is a cancer with the highest incidence and mortality. Alteration of gene expression is the main pathophysiological mechanism of CRC, which results in disturbed signaling pathways and cellular metabolic processes. MicroRNAs are involved in almost all pathophysiological processes and are correlative with colorectal cancer metabolism, proliferation, and chemotherapy resistance. Metabolic reprogramming, an important feature of cancer, is strongly correlative with the development and prognosis of cancers, including colorectal cancer. MicroRNAs can target enzymes involved in metabolic processes, thus playing a regulatory role in tumor metabolism. The disorder of the signaling pathway is another characteristic of tumor, which induces the occurrence and proliferation of tumors, and is closely correlative with the prognosis and chemotherapy resistance of tumor patients. MicroRNAs can target the components of the signaling pathways to regulate their transduction. Understanding the function of microRNAs in the occurrence and proliferation of CRC provides novel insights into the optimal treatment strategies, prognosis, and development of diagnosis in CRC. This article reviews the relationship between CRC and microRNA expression and hopes to provide new options for the diagnosis and treatment of CRC." @default.
• W4385348575 created "2023-07-29" @default.
• W4385348575 creator A5012480415 @default.
• W4385348575 creator A5055229683 @default.
• W4385348575 creator A5064069337 @default.
• W4385348575 creator A5071731158 @default.
• W4385348575 creator A5084296435 @default.
• W4385348575 date "2023-07-27" @default.
• W4385348575 modified "2023-10-14" @default.
• W4385348575 title "Recent advances microRNAs and metabolic reprogramming in colorectal cancer research" @default.
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