Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385352009> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4385352009 endingPage "76" @default.
- W4385352009 startingPage "71" @default.
- W4385352009 abstract "Although Hepatitis C virus (HCV) infection has become a curable disease, the aftermath of the infection remains an important aspect to be evaluated. HCV infection is well known for its extrahepatic manifestations, mostly the tight relationship between HCV, type 2 diabetes mellitus (T2DM) and dyslipidemia. Not only HCV increases the risk of T2DM, but it also affects its control in diabetic patients, increasing the risk of diabetes related complications. Furthermore, HCV hijacks the lipid metabolism resulting in abnormalities in circulating lipids which can lead to multiple complications, such as increased atherosclerotic risk and hepatic steatosis. Objectives. The aim of this study was to evaluate the dynamics of the parameters of carbohydrate and lipid metabolism in HCV-infected diabetic patients compared to non-diabetic patients after viral eradication. Material and methods. This is a prospective study conducted on 100 patients with chronic HVC infection who obtained viral clearance after interferon-free treatment. 58 patients had type 2 diabetes mellitus and 42 were nondiabetic. We evaluated serum total cholesterol, triglycerides, blood glucose and glycosylated hemoglobin in both groups at treatment initiation and 1 year after. Continuous variables were expressed as mean values ± standard deviation or median, categorical variables were represented as relative or absolute frequencies. Characteristics were compared using the Mann-Whitney method or the two-sample Student's T-test method for continuous variables, Chi-square and Fischer's test for categorical variables. A p value < 0.05 was considered statistically significant. Outcomes. The study analyzed and compared lipid and glycemic profiles of diabetic and non-diabetic HVC patients before and after viral cure. Conclusions. 1 year after treatment initiation the changes in lipid metabolism seem to persist, carbohydrate metabolism seems to remain unchanged, with no differences between diabetic and non-diabetic patients." @default.
- W4385352009 created "2023-07-29" @default.
- W4385352009 creator A5000303457 @default.
- W4385352009 creator A5004267564 @default.
- W4385352009 creator A5006265841 @default.
- W4385352009 creator A5009090037 @default.
- W4385352009 creator A5013811687 @default.
- W4385352009 creator A5030007436 @default.
- W4385352009 creator A5038587486 @default.
- W4385352009 creator A5062155663 @default.
- W4385352009 creator A5070115260 @default.
- W4385352009 creator A5075637041 @default.
- W4385352009 creator A5078267391 @default.
- W4385352009 date "2023-06-30" @default.
- W4385352009 modified "2023-10-18" @default.
- W4385352009 title "Evaluation of carbohydrate and lipid metabolism dynamics in chronic HCV diabetic patients treated with direct antiviral agents" @default.
- W4385352009 doi "https://doi.org/10.37897/rjid.2023.2.3" @default.
- W4385352009 hasPublicationYear "2023" @default.
- W4385352009 type Work @default.
- W4385352009 citedByCount "0" @default.
- W4385352009 crossrefType "journal-article" @default.
- W4385352009 hasAuthorship W4385352009A5000303457 @default.
- W4385352009 hasAuthorship W4385352009A5004267564 @default.
- W4385352009 hasAuthorship W4385352009A5006265841 @default.
- W4385352009 hasAuthorship W4385352009A5009090037 @default.
- W4385352009 hasAuthorship W4385352009A5013811687 @default.
- W4385352009 hasAuthorship W4385352009A5030007436 @default.
- W4385352009 hasAuthorship W4385352009A5038587486 @default.
- W4385352009 hasAuthorship W4385352009A5062155663 @default.
- W4385352009 hasAuthorship W4385352009A5070115260 @default.
- W4385352009 hasAuthorship W4385352009A5075637041 @default.
- W4385352009 hasAuthorship W4385352009A5078267391 @default.
- W4385352009 hasBestOaLocation W43853520091 @default.
- W4385352009 hasConcept C126322002 @default.
- W4385352009 hasConcept C134018914 @default.
- W4385352009 hasConcept C17093226 @default.
- W4385352009 hasConcept C203014093 @default.
- W4385352009 hasConcept C2522874641 @default.
- W4385352009 hasConcept C2776175330 @default.
- W4385352009 hasConcept C2776408679 @default.
- W4385352009 hasConcept C2776455275 @default.
- W4385352009 hasConcept C2777391703 @default.
- W4385352009 hasConcept C2778096610 @default.
- W4385352009 hasConcept C2778270857 @default.
- W4385352009 hasConcept C2779306644 @default.
- W4385352009 hasConcept C2780473172 @default.
- W4385352009 hasConcept C2910068830 @default.
- W4385352009 hasConcept C4733338 @default.
- W4385352009 hasConcept C555293320 @default.
- W4385352009 hasConcept C71924100 @default.
- W4385352009 hasConcept C90924648 @default.
- W4385352009 hasConceptScore W4385352009C126322002 @default.
- W4385352009 hasConceptScore W4385352009C134018914 @default.
- W4385352009 hasConceptScore W4385352009C17093226 @default.
- W4385352009 hasConceptScore W4385352009C203014093 @default.
- W4385352009 hasConceptScore W4385352009C2522874641 @default.
- W4385352009 hasConceptScore W4385352009C2776175330 @default.
- W4385352009 hasConceptScore W4385352009C2776408679 @default.
- W4385352009 hasConceptScore W4385352009C2776455275 @default.
- W4385352009 hasConceptScore W4385352009C2777391703 @default.
- W4385352009 hasConceptScore W4385352009C2778096610 @default.
- W4385352009 hasConceptScore W4385352009C2778270857 @default.
- W4385352009 hasConceptScore W4385352009C2779306644 @default.
- W4385352009 hasConceptScore W4385352009C2780473172 @default.
- W4385352009 hasConceptScore W4385352009C2910068830 @default.
- W4385352009 hasConceptScore W4385352009C4733338 @default.
- W4385352009 hasConceptScore W4385352009C555293320 @default.
- W4385352009 hasConceptScore W4385352009C71924100 @default.
- W4385352009 hasConceptScore W4385352009C90924648 @default.
- W4385352009 hasIssue "2" @default.
- W4385352009 hasLocation W43853520091 @default.
- W4385352009 hasOpenAccess W4385352009 @default.
- W4385352009 hasPrimaryLocation W43853520091 @default.
- W4385352009 hasRelatedWork W138803513 @default.
- W4385352009 hasRelatedWork W1986132654 @default.
- W4385352009 hasRelatedWork W2010140898 @default.
- W4385352009 hasRelatedWork W2023313620 @default.
- W4385352009 hasRelatedWork W2044823377 @default.
- W4385352009 hasRelatedWork W2054690921 @default.
- W4385352009 hasRelatedWork W2082140668 @default.
- W4385352009 hasRelatedWork W2087100186 @default.
- W4385352009 hasRelatedWork W4234612679 @default.
- W4385352009 hasRelatedWork W4385769413 @default.
- W4385352009 hasVolume "26" @default.
- W4385352009 isParatext "false" @default.
- W4385352009 isRetracted "false" @default.
- W4385352009 workType "article" @default.