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- W4385355378 abstract "Multiple studies have shown that the activity of alkaline phosphatase (AP) increases during Alzheimer's disease (AD). In this paper, using UV-Visible spectroscopy, we show that this increase in activity is due to its interaction with key components of AD such as amyloid β peptide and acetylcholinesterase. Activity increase also occurs due to high concentrations of acetylcholine and choline. These conditions are present in AD or could occur due to drugs used for treating AD." @default.
- W4385355378 created "2023-07-29" @default.
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- W4385355378 date "2023-01-01" @default.
- W4385355378 modified "2023-10-16" @default.
- W4385355378 title "Interactions with amyloid beta peptide and acetylcholinesterase increase alkaline phosphatase activity" @default.
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- W4385355378 doi "https://doi.org/10.1039/d3cp01480k" @default.
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