FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385358834> ?p ?o ?g. }

• W4385358834 abstract "The incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma has increased dramatically in recent years reaching epidemic-like proportions. Data has emerged not only showing that these cancers are a unique entity with distinct molecular characteristics but that they also have a significantly improved prognosis as a result of their exquisite radiosensitivity compared to their HPV-negative counterparts. This, it has been increasingly suggested that these tumors can be targeted with de-escalated approaches using reduced doses of radiation. The overriding goal of de-escalation is to maintain the high cure and survival rates associated with traditional approaches while reducing the incidence of both short- and long-term toxicity. Although the exact reason for the improved radiosensitivity of HPV-positive oropharyngeal carcinoma is unclear, prospective studies have now been published demonstrating that de-escalated radiation can successfully maintain the high rates of cure and preserve quality of life for appropriately selected patients with this disease. However, these studies have been complicated by such factors as the relatively limited sample sizes, as well as the variability in treatment, inclusion criteria, and follow-up. As the data continues to mature on de-escalation, it is unquestionable that treatment paradigms for this disease will evolve. The ongoing quest to define a standard regimen comprises the subject of this review." @default.
• W4385358834 created "2023-07-29" @default.
• W4385358834 creator A5001312226 @default.
• W4385358834 date "2023-07-27" @default.
• W4385358834 modified "2023-10-18" @default.
• W4385358834 title "De-escalated radiation for human papillomavirus virus-related oropharyngeal cancer: evolving paradigms and future strategies" @default.
• W4385358834 cites W1555202011 @default.
• W4385358834 cites W1556413243 @default.
• W4385358834 cites W1559340156 @default.
• W4385358834 cites W1587143876 @default.
• W4385358834 cites W1743023502 @default.
• W4385358834 cites W1804125372 @default.
• W4385358834 cites W1967407594 @default.
• W4385358834 cites W1981244332 @default.
• W4385358834 cites W1982191980 @default.
• W4385358834 cites W1986241711 @default.
• W4385358834 cites W2005574374 @default.
• W4385358834 cites W2030023766 @default.
• W4385358834 cites W2031309489 @default.
• W4385358834 cites W2036697383 @default.
• W4385358834 cites W2039387720 @default.
• W4385358834 cites W2041802539 @default.
• W4385358834 cites W2061572018 @default.
• W4385358834 cites W2068106568 @default.
• W4385358834 cites W2071606440 @default.
• W4385358834 cites W2096025553 @default.
• W4385358834 cites W2101146042 @default.
• W4385358834 cites W2105050382 @default.
• W4385358834 cites W2110664940 @default.
• W4385358834 cites W2111442242 @default.
• W4385358834 cites W2114119309 @default.
• W4385358834 cites W2114909947 @default.
• W4385358834 cites W2117183231 @default.
• W4385358834 cites W2118772763 @default.
• W4385358834 cites W2118921797 @default.
• W4385358834 cites W2122035130 @default.
• W4385358834 cites W2123526038 @default.
• W4385358834 cites W2127605299 @default.
• W4385358834 cites W2136409533 @default.
• W4385358834 cites W2141859344 @default.
• W4385358834 cites W2147467272 @default.
• W4385358834 cites W2169374604 @default.
• W4385358834 cites W2303803372 @default.
• W4385358834 cites W2320299038 @default.
• W4385358834 cites W2335162820 @default.
• W4385358834 cites W2345692510 @default.
• W4385358834 cites W2347184903 @default.
• W4385358834 cites W2502134830 @default.
• W4385358834 cites W2566106337 @default.
• W4385358834 cites W2583327680 @default.
• W4385358834 cites W2607491790 @default.
• W4385358834 cites W2659668647 @default.
• W4385358834 cites W2752852643 @default.
• W4385358834 cites W2763263441 @default.
• W4385358834 cites W2765798901 @default.
• W4385358834 cites W2767419444 @default.
• W4385358834 cites W2800754182 @default.
• W4385358834 cites W2803082375 @default.
• W4385358834 cites W2808824285 @default.
• W4385358834 cites W2886259079 @default.
• W4385358834 cites W2891596321 @default.
• W4385358834 cites W2892876553 @default.
• W4385358834 cites W2901263658 @default.
• W4385358834 cites W2901385432 @default.
• W4385358834 cites W2902299732 @default.
• W4385358834 cites W2905193937 @default.
• W4385358834 cites W2907105689 @default.
• W4385358834 cites W2911675656 @default.
• W4385358834 cites W2912454709 @default.
• W4385358834 cites W2914319149 @default.
• W4385358834 cites W2938900163 @default.
• W4385358834 cites W2941618015 @default.
• W4385358834 cites W2942765569 @default.
• W4385358834 cites W2945478948 @default.
• W4385358834 cites W2945826604 @default.
• W4385358834 cites W2948644893 @default.
• W4385358834 cites W2955174416 @default.
• W4385358834 cites W2967453129 @default.
• W4385358834 cites W2968987551 @default.
• W4385358834 cites W2973690129 @default.
• W4385358834 cites W2990489672 @default.
• W4385358834 cites W2990928595 @default.
• W4385358834 cites W2992301262 @default.
• W4385358834 cites W2995316333 @default.
• W4385358834 cites W3003653123 @default.
• W4385358834 cites W3005641209 @default.
• W4385358834 cites W3011535061 @default.
• W4385358834 cites W3018270587 @default.
• W4385358834 cites W3023215227 @default.
• W4385358834 cites W3028350593 @default.
• W4385358834 cites W3042152885 @default.
• W4385358834 cites W3042659257 @default.
• W4385358834 cites W3043613101 @default.
• W4385358834 cites W3046572970 @default.
• W4385358834 cites W3046898995 @default.
• W4385358834 cites W3093234744 @default.
• W4385358834 cites W3117653624 @default.
• W4385358834 cites W3119504480 @default.
• W4385358834 cites W3122345229 @default.
• W4385358834 cites W3147500389 @default.

• next