Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385361336> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4385361336 endingPage "106" @default.
- W4385361336 startingPage "106" @default.
- W4385361336 abstract "Microglial activation is considered to assume a role in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). To date, the relationship between ALS and the rs3865444 polymorphism of the cluster of differentiation 33 (CD33) has not been explored. The current report aimed to investigate the potential connection between CD33 rs3865444 and ALS.Patients diagnosed with sporadic ALS according to the revised El Escorial criteria, as well as age and sex matched community controls, were enrolled. Two evenly numbered, age and sex matched groups of 155 participants each were genotyped.No association was found between rs3865444 and ALS [log-additive odds ratio (OR) = 0.83 (0.57, 1.22), over-dominant OR = 0.86 (0.55, 1.36), recessive OR = 0.73 (0.25, 2.17), dominant OR = 0.82 (0.52, 1.29), co-dominant OR1 = 0.68 (0.23, 2.05) and co-dominant OR2 = 0.84 (0.53, 1.33)]. Moreover, no relationship was established between rs3865444 and the age of ALS onset based on both unadjusted and sex adjusted Cox-proportional hazards models. Finally, no association between rs3865444 and ALS was found in subgroup analyses based on the site of ALS onset (bulbar or spinal) and sex.The current analysis is the first to report that rs3865444 is not linked to ALS. Larger multi-racial studies are required to confirm these findings." @default.
- W4385361336 created "2023-07-29" @default.
- W4385361336 creator A5004326313 @default.
- W4385361336 creator A5005420378 @default.
- W4385361336 creator A5008309468 @default.
- W4385361336 creator A5018705575 @default.
- W4385361336 creator A5020623639 @default.
- W4385361336 creator A5020865216 @default.
- W4385361336 creator A5032663940 @default.
- W4385361336 creator A5042914297 @default.
- W4385361336 creator A5046916516 @default.
- W4385361336 creator A5070425998 @default.
- W4385361336 creator A5070925692 @default.
- W4385361336 creator A5074264303 @default.
- W4385361336 creator A5088357240 @default.
- W4385361336 date "2023-07-26" @default.
- W4385361336 modified "2023-09-27" @default.
- W4385361336 title "Lack of Association between CD33 rs3865444 and Amyotrophic Lateral Sclerosis: A Case-Control Study" @default.
- W4385361336 doi "https://doi.org/10.31083/j.jin2204106" @default.
- W4385361336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37519183" @default.
- W4385361336 hasPublicationYear "2023" @default.
- W4385361336 type Work @default.
- W4385361336 citedByCount "0" @default.
- W4385361336 crossrefType "journal-article" @default.
- W4385361336 hasAuthorship W4385361336A5004326313 @default.
- W4385361336 hasAuthorship W4385361336A5005420378 @default.
- W4385361336 hasAuthorship W4385361336A5008309468 @default.
- W4385361336 hasAuthorship W4385361336A5018705575 @default.
- W4385361336 hasAuthorship W4385361336A5020623639 @default.
- W4385361336 hasAuthorship W4385361336A5020865216 @default.
- W4385361336 hasAuthorship W4385361336A5032663940 @default.
- W4385361336 hasAuthorship W4385361336A5042914297 @default.
- W4385361336 hasAuthorship W4385361336A5046916516 @default.
- W4385361336 hasAuthorship W4385361336A5070425998 @default.
- W4385361336 hasAuthorship W4385361336A5070925692 @default.
- W4385361336 hasAuthorship W4385361336A5074264303 @default.
- W4385361336 hasAuthorship W4385361336A5088357240 @default.
- W4385361336 hasBestOaLocation W43853613361 @default.
- W4385361336 hasConcept C126322002 @default.
- W4385361336 hasConcept C143998085 @default.
- W4385361336 hasConcept C156957248 @default.
- W4385361336 hasConcept C15744967 @default.
- W4385361336 hasConcept C2779134260 @default.
- W4385361336 hasConcept C2780596555 @default.
- W4385361336 hasConcept C2780942790 @default.
- W4385361336 hasConcept C50382708 @default.
- W4385361336 hasConcept C71924100 @default.
- W4385361336 hasConceptScore W4385361336C126322002 @default.
- W4385361336 hasConceptScore W4385361336C143998085 @default.
- W4385361336 hasConceptScore W4385361336C156957248 @default.
- W4385361336 hasConceptScore W4385361336C15744967 @default.
- W4385361336 hasConceptScore W4385361336C2779134260 @default.
- W4385361336 hasConceptScore W4385361336C2780596555 @default.
- W4385361336 hasConceptScore W4385361336C2780942790 @default.
- W4385361336 hasConceptScore W4385361336C50382708 @default.
- W4385361336 hasConceptScore W4385361336C71924100 @default.
- W4385361336 hasIssue "4" @default.
- W4385361336 hasLocation W43853613361 @default.
- W4385361336 hasLocation W43853613362 @default.
- W4385361336 hasOpenAccess W4385361336 @default.
- W4385361336 hasPrimaryLocation W43853613361 @default.
- W4385361336 hasRelatedWork W1979828201 @default.
- W4385361336 hasRelatedWork W1999363671 @default.
- W4385361336 hasRelatedWork W2086095107 @default.
- W4385361336 hasRelatedWork W2184157503 @default.
- W4385361336 hasRelatedWork W2350328980 @default.
- W4385361336 hasRelatedWork W2417924878 @default.
- W4385361336 hasRelatedWork W2748952813 @default.
- W4385361336 hasRelatedWork W2899084033 @default.
- W4385361336 hasRelatedWork W4284960801 @default.
- W4385361336 hasRelatedWork W601357221 @default.
- W4385361336 hasVolume "22" @default.
- W4385361336 isParatext "false" @default.
- W4385361336 isRetracted "false" @default.
- W4385361336 workType "article" @default.