Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385367069> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W4385367069 abstract "Abstract Purpose In 2019, the National Comprehensive Cancer Network (NCCN) recommended genetic testing for all patients with pancreatic ductal adenocarcinoma (PDAC). To evaluate the status of implementation of these guidelines in a loco-regional setting, we performed a retrospective, observational study among patients with newly diagnosed PDAC who received oncologic care at Northeast Georgia Medical Center in Georgia. Methods Chart abstraction of patients with newly diagnosed PDAC from January 1, 2020 to December 31, 2021, was performed to include information on genetic testing recommendation and completion, and time from diagnosis to testing. The deidentified dataset was then analyzed using appropriate descriptive and associative statistical testing. Results Of the cohort of 109 patients, 32 (29.4%) completed genetic screening; 16 (14.7%) were screened within 10 days of diagnosis. Among the 77 (70.6%) patients who did not receive genetic screening, 45 (41.3%) were not recommended genetic screening despite treatment intent with standard of care therapy. However, 32 (29.4%) were not recommended genetic screening in conjunction with a desire to pursue palliative care/hospice/or due to terminal illness. Conclusions The study highlighted the gap in implementation of NCCN guideline-directed genetic testing in PDAC patients as only a third underwent testing suggesting the need for systematic processes to facilitate testing. The test was more likely to be completed if done early in the course, especially soon after the diagnosis. Research is needed to explore discussing genetic testing for the large proportion of patients who are terminally ill at diagnosis where genetic screening would potentially benefit the family members." @default.
- W4385367069 created "2023-07-29" @default.
- W4385367069 creator A5015249824 @default.
- W4385367069 creator A5017078421 @default.
- W4385367069 creator A5029739774 @default.
- W4385367069 creator A5038777527 @default.
- W4385367069 creator A5057649650 @default.
- W4385367069 creator A5068872368 @default.
- W4385367069 date "2023-07-27" @default.
- W4385367069 modified "2023-09-23" @default.
- W4385367069 title "Evaluating Implementation of NCCN Guideline-Directed Genetic Screening Recommendations for Patients with Pancreatic Ductal Adenocarcinoma" @default.
- W4385367069 cites W2092259915 @default.
- W4385367069 cites W2158048150 @default.
- W4385367069 cites W2522369252 @default.
- W4385367069 cites W2809494794 @default.
- W4385367069 cites W2901026062 @default.
- W4385367069 cites W3036222180 @default.
- W4385367069 cites W3106631792 @default.
- W4385367069 cites W3119723210 @default.
- W4385367069 cites W3157801830 @default.
- W4385367069 cites W4200563399 @default.
- W4385367069 cites W4210591206 @default.
- W4385367069 cites W4224444625 @default.
- W4385367069 cites W4315754639 @default.
- W4385367069 doi "https://doi.org/10.21203/rs.3.rs-3179755/v1" @default.
- W4385367069 hasPublicationYear "2023" @default.
- W4385367069 type Work @default.
- W4385367069 citedByCount "0" @default.
- W4385367069 crossrefType "posted-content" @default.
- W4385367069 hasAuthorship W4385367069A5015249824 @default.
- W4385367069 hasAuthorship W4385367069A5017078421 @default.
- W4385367069 hasAuthorship W4385367069A5029739774 @default.
- W4385367069 hasAuthorship W4385367069A5038777527 @default.
- W4385367069 hasAuthorship W4385367069A5057649650 @default.
- W4385367069 hasAuthorship W4385367069A5068872368 @default.
- W4385367069 hasBestOaLocation W43853670691 @default.
- W4385367069 hasConcept C121608353 @default.
- W4385367069 hasConcept C126322002 @default.
- W4385367069 hasConcept C142724271 @default.
- W4385367069 hasConcept C143998085 @default.
- W4385367069 hasConcept C167135981 @default.
- W4385367069 hasConcept C23131810 @default.
- W4385367069 hasConcept C2780182762 @default.
- W4385367069 hasConcept C2780210213 @default.
- W4385367069 hasConcept C2780673598 @default.
- W4385367069 hasConcept C512399662 @default.
- W4385367069 hasConcept C54355233 @default.
- W4385367069 hasConcept C71924100 @default.
- W4385367069 hasConcept C72563966 @default.
- W4385367069 hasConcept C80227256 @default.
- W4385367069 hasConcept C86803240 @default.
- W4385367069 hasConceptScore W4385367069C121608353 @default.
- W4385367069 hasConceptScore W4385367069C126322002 @default.
- W4385367069 hasConceptScore W4385367069C142724271 @default.
- W4385367069 hasConceptScore W4385367069C143998085 @default.
- W4385367069 hasConceptScore W4385367069C167135981 @default.
- W4385367069 hasConceptScore W4385367069C23131810 @default.
- W4385367069 hasConceptScore W4385367069C2780182762 @default.
- W4385367069 hasConceptScore W4385367069C2780210213 @default.
- W4385367069 hasConceptScore W4385367069C2780673598 @default.
- W4385367069 hasConceptScore W4385367069C512399662 @default.
- W4385367069 hasConceptScore W4385367069C54355233 @default.
- W4385367069 hasConceptScore W4385367069C71924100 @default.
- W4385367069 hasConceptScore W4385367069C72563966 @default.
- W4385367069 hasConceptScore W4385367069C80227256 @default.
- W4385367069 hasConceptScore W4385367069C86803240 @default.
- W4385367069 hasLocation W43853670691 @default.
- W4385367069 hasOpenAccess W4385367069 @default.
- W4385367069 hasPrimaryLocation W43853670691 @default.
- W4385367069 hasRelatedWork W2018982142 @default.
- W4385367069 hasRelatedWork W2039875111 @default.
- W4385367069 hasRelatedWork W2052700799 @default.
- W4385367069 hasRelatedWork W2551647681 @default.
- W4385367069 hasRelatedWork W2744030789 @default.
- W4385367069 hasRelatedWork W2983896041 @default.
- W4385367069 hasRelatedWork W3159319878 @default.
- W4385367069 hasRelatedWork W3199860621 @default.
- W4385367069 hasRelatedWork W3207076912 @default.
- W4385367069 hasRelatedWork W4207019024 @default.
- W4385367069 isParatext "false" @default.
- W4385367069 isRetracted "false" @default.
- W4385367069 workType "article" @default.