Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385383600> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W4385383600 endingPage "101055" @default.
- W4385383600 startingPage "101055" @default.
- W4385383600 abstract "Biosimilars are emerging class of medications that are very similar to biologics (in terms of safety and efficacy to the original reference product); but not the same as generic, originating, or reference drugs. The availability and use of biosimilars in oncology landscape are slowly picking, thereby combating financial burden to cancer patients. Breast cancer, with a staggering number of cases recently, has become the most common cancer in females. Human epidermal growth factor receptor-2 (HER2)-positive breast cancer involves the cell-surface protein that causes cell growth and proliferation and is more aggressive than typical breast cancer. The emergence of trastuzumab (first oncogene-targeted therapeutic agent for solid tumours to be clinically available under the brand name Herceptin) has improved the scope for patients suffering from this type of breast cancer. However, the associated cost remains to be a significant barrier for patients with breast cancer to access this treatment. Biosimilars, since their relatively recent advent, have reduced the cost of cancer treatment significantly, and will continue to play important cost-effective therapeutic roles for years to come. Notably, healthcare professionals still bear a somewhat negative/reluctant connotation to biosimilars. This article attempts to describe and analyse the studies that have been published in peer-reviewed literature on the use of trastuzumab biosimilars and their efficacy, safety, pharmacokinetic, and pharmacodynamic properties. It also covers on the chemistry and clinical advantages of using biosimilars for the ongoing and future treatment prospects for patients with breast cancer." @default.
- W4385383600 created "2023-07-30" @default.
- W4385383600 creator A5040010155 @default.
- W4385383600 creator A5092567105 @default.
- W4385383600 date "2023-12-01" @default.
- W4385383600 modified "2023-10-01" @default.
- W4385383600 title "Emerging role of biosimilars: Focus on trastuzumab and metastatic human epidermal growth factor receptor 2-positive breast cancer" @default.
- W4385383600 cites W2210363578 @default.
- W4385383600 cites W2212833401 @default.
- W4385383600 cites W2530856438 @default.
- W4385383600 cites W2608742892 @default.
- W4385383600 cites W2783013874 @default.
- W4385383600 cites W2785217251 @default.
- W4385383600 cites W2793544934 @default.
- W4385383600 cites W2806386505 @default.
- W4385383600 cites W2820616462 @default.
- W4385383600 cites W2890356222 @default.
- W4385383600 cites W2894783409 @default.
- W4385383600 cites W2901213712 @default.
- W4385383600 cites W2904920769 @default.
- W4385383600 cites W2909868666 @default.
- W4385383600 cites W2939055585 @default.
- W4385383600 cites W2943657996 @default.
- W4385383600 cites W2945697388 @default.
- W4385383600 cites W2949358313 @default.
- W4385383600 cites W2969231750 @default.
- W4385383600 cites W2969549294 @default.
- W4385383600 cites W2972850303 @default.
- W4385383600 cites W2984412140 @default.
- W4385383600 cites W2999909818 @default.
- W4385383600 cites W3038021296 @default.
- W4385383600 cites W3080544563 @default.
- W4385383600 cites W3080572958 @default.
- W4385383600 cites W3090425273 @default.
- W4385383600 cites W3090684381 @default.
- W4385383600 cites W3095756671 @default.
- W4385383600 cites W3099557102 @default.
- W4385383600 cites W3126227289 @default.
- W4385383600 cites W3131504571 @default.
- W4385383600 cites W3149458367 @default.
- W4385383600 cites W3166492122 @default.
- W4385383600 cites W3167821594 @default.
- W4385383600 cites W3175977373 @default.
- W4385383600 cites W3184426087 @default.
- W4385383600 cites W3193347331 @default.
- W4385383600 cites W4210840590 @default.
- W4385383600 cites W4283029993 @default.
- W4385383600 cites W4292548548 @default.
- W4385383600 cites W4313855606 @default.
- W4385383600 cites W4315926042 @default.
- W4385383600 doi "https://doi.org/10.1016/j.rechem.2023.101055" @default.
- W4385383600 hasPublicationYear "2023" @default.
- W4385383600 type Work @default.
- W4385383600 citedByCount "0" @default.
- W4385383600 crossrefType "journal-article" @default.
- W4385383600 hasAuthorship W4385383600A5040010155 @default.
- W4385383600 hasAuthorship W4385383600A5092567105 @default.
- W4385383600 hasBestOaLocation W43853836001 @default.
- W4385383600 hasConcept C121608353 @default.
- W4385383600 hasConcept C126322002 @default.
- W4385383600 hasConcept C143998085 @default.
- W4385383600 hasConcept C2775930923 @default.
- W4385383600 hasConcept C2779438470 @default.
- W4385383600 hasConcept C2779786085 @default.
- W4385383600 hasConcept C530470458 @default.
- W4385383600 hasConcept C59491497 @default.
- W4385383600 hasConcept C71924100 @default.
- W4385383600 hasConceptScore W4385383600C121608353 @default.
- W4385383600 hasConceptScore W4385383600C126322002 @default.
- W4385383600 hasConceptScore W4385383600C143998085 @default.
- W4385383600 hasConceptScore W4385383600C2775930923 @default.
- W4385383600 hasConceptScore W4385383600C2779438470 @default.
- W4385383600 hasConceptScore W4385383600C2779786085 @default.
- W4385383600 hasConceptScore W4385383600C530470458 @default.
- W4385383600 hasConceptScore W4385383600C59491497 @default.
- W4385383600 hasConceptScore W4385383600C71924100 @default.
- W4385383600 hasLocation W43853836001 @default.
- W4385383600 hasOpenAccess W4385383600 @default.
- W4385383600 hasPrimaryLocation W43853836001 @default.
- W4385383600 hasRelatedWork W2761333960 @default.
- W4385383600 hasRelatedWork W2794755138 @default.
- W4385383600 hasRelatedWork W2934222321 @default.
- W4385383600 hasRelatedWork W2998101594 @default.
- W4385383600 hasRelatedWork W3087766662 @default.
- W4385383600 hasRelatedWork W3137327078 @default.
- W4385383600 hasRelatedWork W3202363710 @default.
- W4385383600 hasRelatedWork W4287922124 @default.
- W4385383600 hasRelatedWork W4292478226 @default.
- W4385383600 hasRelatedWork W2342209702 @default.
- W4385383600 hasVolume "6" @default.
- W4385383600 isParatext "false" @default.
- W4385383600 isRetracted "false" @default.
- W4385383600 workType "article" @default.