Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385389384> ?p ?o ?g. }
- W4385389384 endingPage "131228" @default.
- W4385389384 startingPage "131228" @default.
- W4385389384 abstract "Cardiovascular (CV) disease is preventable through interventions targeting modifiable factors. Most algorithms based on modifiable CV risk factors (CV-rf) have been developed in US populations and do not account for the role of diet. We aimed to assess an algorithm based on modifiable CV-rf including diet, using data from an Italian population.To derive the Moli-sani Risk Score (MRS), we used data on 16,656 men and women (age ≥ 35 y) from the population of the Moli-sani Study. The Risk-and-Prevention-Study, Italy (N = 8606) acted as external validation cohort and the Life's-Simple-7 score was used as benchmark. The MRS targeted at fatal or non-fatal CV events and included 9 common modifiable CV-rf.After 8.1 years (median) of follow-up, 816 events occurred in the derivation cohort. The MRS was calculated as a weighted sum of its 9 components, with weights reflecting the strength of the association. In comparison with individuals in the first, those in the fourth quartile of the score had hazard ratio (HR) for CV events equal to 3.18 (95%CI: 2.54-3.97). One more point in the score was associated with 7% (6%-8%) and 4% (3%-5%) higher hazard of events in the derivation and validation cohort, respectively. The MRS performed better than the Life's Simple-7 for discrimination.We propose the Moli-sani Risk Score, a validated, performing algorithm able to measure the combined impact that modifiable CV-rf have on CV risk. The score can be used to design preventive interventions, quantify the effectiveness of interventions, and compare different preventive strategies." @default.
- W4385389384 created "2023-07-30" @default.
- W4385389384 creator A5009323040 @default.
- W4385389384 creator A5010557706 @default.
- W4385389384 creator A5018220482 @default.
- W4385389384 creator A5025599058 @default.
- W4385389384 creator A5033092400 @default.
- W4385389384 creator A5033370052 @default.
- W4385389384 creator A5047508408 @default.
- W4385389384 creator A5059583414 @default.
- W4385389384 creator A5064679425 @default.
- W4385389384 creator A5066772645 @default.
- W4385389384 creator A5069797729 @default.
- W4385389384 creator A5076610908 @default.
- W4385389384 creator A5085040629 @default.
- W4385389384 creator A5089109611 @default.
- W4385389384 date "2023-10-01" @default.
- W4385389384 modified "2023-09-26" @default.
- W4385389384 title "The Moli-sani risk score, a new algorithm for measuring the global impact of modifiable cardiovascular risk factors" @default.
- W4385389384 cites W2000745019 @default.
- W4385389384 cites W2014315605 @default.
- W4385389384 cites W205947756 @default.
- W4385389384 cites W2065306786 @default.
- W4385389384 cites W2117762755 @default.
- W4385389384 cites W2121236256 @default.
- W4385389384 cites W2127652808 @default.
- W4385389384 cites W2133493397 @default.
- W4385389384 cites W2134796344 @default.
- W4385389384 cites W2152436391 @default.
- W4385389384 cites W2156848121 @default.
- W4385389384 cites W2157622195 @default.
- W4385389384 cites W2332987513 @default.
- W4385389384 cites W2391138069 @default.
- W4385389384 cites W2612135195 @default.
- W4385389384 cites W2614282478 @default.
- W4385389384 cites W2618321252 @default.
- W4385389384 cites W2791275456 @default.
- W4385389384 cites W2802410718 @default.
- W4385389384 cites W2807970930 @default.
- W4385389384 cites W2904059000 @default.
- W4385389384 cites W2909351915 @default.
- W4385389384 cites W2956035425 @default.
- W4385389384 cites W2999749765 @default.
- W4385389384 cites W3089208272 @default.
- W4385389384 cites W3109609494 @default.
- W4385389384 cites W3166015112 @default.
- W4385389384 doi "https://doi.org/10.1016/j.ijcard.2023.131228" @default.
- W4385389384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37527754" @default.
- W4385389384 hasPublicationYear "2023" @default.
- W4385389384 type Work @default.
- W4385389384 citedByCount "0" @default.
- W4385389384 crossrefType "journal-article" @default.
- W4385389384 hasAuthorship W4385389384A5009323040 @default.
- W4385389384 hasAuthorship W4385389384A5010557706 @default.
- W4385389384 hasAuthorship W4385389384A5018220482 @default.
- W4385389384 hasAuthorship W4385389384A5025599058 @default.
- W4385389384 hasAuthorship W4385389384A5033092400 @default.
- W4385389384 hasAuthorship W4385389384A5033370052 @default.
- W4385389384 hasAuthorship W4385389384A5047508408 @default.
- W4385389384 hasAuthorship W4385389384A5059583414 @default.
- W4385389384 hasAuthorship W4385389384A5064679425 @default.
- W4385389384 hasAuthorship W4385389384A5066772645 @default.
- W4385389384 hasAuthorship W4385389384A5069797729 @default.
- W4385389384 hasAuthorship W4385389384A5076610908 @default.
- W4385389384 hasAuthorship W4385389384A5085040629 @default.
- W4385389384 hasAuthorship W4385389384A5089109611 @default.
- W4385389384 hasConcept C11413529 @default.
- W4385389384 hasConcept C11783203 @default.
- W4385389384 hasConcept C12174686 @default.
- W4385389384 hasConcept C126322002 @default.
- W4385389384 hasConcept C201903717 @default.
- W4385389384 hasConcept C207103383 @default.
- W4385389384 hasConcept C2779134260 @default.
- W4385389384 hasConcept C2908647359 @default.
- W4385389384 hasConcept C33923547 @default.
- W4385389384 hasConcept C38652104 @default.
- W4385389384 hasConcept C41008148 @default.
- W4385389384 hasConcept C44249647 @default.
- W4385389384 hasConcept C50382708 @default.
- W4385389384 hasConcept C68443243 @default.
- W4385389384 hasConcept C71924100 @default.
- W4385389384 hasConcept C72563966 @default.
- W4385389384 hasConcept C99454951 @default.
- W4385389384 hasConceptScore W4385389384C11413529 @default.
- W4385389384 hasConceptScore W4385389384C11783203 @default.
- W4385389384 hasConceptScore W4385389384C12174686 @default.
- W4385389384 hasConceptScore W4385389384C126322002 @default.
- W4385389384 hasConceptScore W4385389384C201903717 @default.
- W4385389384 hasConceptScore W4385389384C207103383 @default.
- W4385389384 hasConceptScore W4385389384C2779134260 @default.
- W4385389384 hasConceptScore W4385389384C2908647359 @default.
- W4385389384 hasConceptScore W4385389384C33923547 @default.
- W4385389384 hasConceptScore W4385389384C38652104 @default.
- W4385389384 hasConceptScore W4385389384C41008148 @default.
- W4385389384 hasConceptScore W4385389384C44249647 @default.
- W4385389384 hasConceptScore W4385389384C50382708 @default.
- W4385389384 hasConceptScore W4385389384C68443243 @default.
- W4385389384 hasConceptScore W4385389384C71924100 @default.