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- W4385406853 abstract "Type 2 diabetes (T2DM) is a complex metabolic disorder manifested by hyperglycemia, insulin resistance, and deteriorating beta-cell function. A way to prevent progression of the disease might be to enhance beta-cell function and insulin secretion. However, most previous studies examined beta-cell function while patients were using glycemia-lowering agents without an adequate period off medications (washout). In the present review we focus on studies with a washout period. We performed a literature search (2010 to June 2021) using beta-cell function and enhancement. The evidence shows that beta-cell function can be enhanced. Bariatric surgery and very low calorie diets show improvement in beta-cell function in many individuals. In addition, use of glucagon-like peptide-1 receptor agonists for prolonged periods (3 years or more) can also lead to improvement of beta-cell function. Further research is needed to understand the mechanisms leading to improved beta-cell function and identify agents that could enhance beta-cell function in patients with T2DM." @default.
- W4385406853 created "2023-08-01" @default.
- W4385406853 creator A5011105274 @default.
- W4385406853 creator A5043779785 @default.
- W4385406853 creator A5062695308 @default.
- W4385406853 creator A5063484171 @default.
- W4385406853 date "2023-07-31" @default.
- W4385406853 modified "2023-09-27" @default.
- W4385406853 title "Beta‐cell function in type 2 diabetes (<scp>T2DM</scp>): Can it be preserved or enhanced?" @default.
- W4385406853 cites W11872906 @default.
- W4385406853 cites W1538553036 @default.
- W4385406853 cites W1570888466 @default.
- W4385406853 cites W1635498832 @default.
- W4385406853 cites W1896609300 @default.
- W4385406853 cites W1961236915 @default.
- W4385406853 cites W1967005515 @default.
- W4385406853 cites W1967406107 @default.
- W4385406853 cites W1970727299 @default.
- W4385406853 cites W1975663485 @default.
- W4385406853 cites W1983099475 @default.
- W4385406853 cites W1984513597 @default.
- W4385406853 cites W1984740259 @default.
- W4385406853 cites W1986085856 @default.
- W4385406853 cites W2003454094 @default.
- W4385406853 cites W2006194480 @default.
- W4385406853 cites W2006538339 @default.
- W4385406853 cites W2016802555 @default.
- W4385406853 cites W2019570781 @default.
- W4385406853 cites W2021584674 @default.
- W4385406853 cites W2024705093 @default.
- W4385406853 cites W202493534 @default.
- W4385406853 cites W2025544664 @default.
- W4385406853 cites W2026423521 @default.
- W4385406853 cites W2032487852 @default.
- W4385406853 cites W2032773959 @default.
- W4385406853 cites W2048565142 @default.
- W4385406853 cites W2051568878 @default.
- W4385406853 cites W2054821923 @default.
- W4385406853 cites W2056319298 @default.
- W4385406853 cites W2060743272 @default.
- W4385406853 cites W2061309116 @default.
- W4385406853 cites W2061574308 @default.
- W4385406853 cites W2067820229 @default.
- W4385406853 cites W2069665789 @default.
- W4385406853 cites W2070658519 @default.
- W4385406853 cites W2076984646 @default.
- W4385406853 cites W2080546358 @default.
- W4385406853 cites W2085390992 @default.
- W4385406853 cites W2094434238 @default.
- W4385406853 cites W2096773810 @default.
- W4385406853 cites W2100968639 @default.
- W4385406853 cites W2102263935 @default.
- W4385406853 cites W2102400698 @default.
- W4385406853 cites W2105497606 @default.
- W4385406853 cites W2105912552 @default.
- W4385406853 cites W2106709311 @default.
- W4385406853 cites W2111497885 @default.
- W4385406853 cites W2112286580 @default.
- W4385406853 cites W2112535191 @default.
- W4385406853 cites W2113544353 @default.
- W4385406853 cites W2116380331 @default.
- W4385406853 cites W2123922428 @default.
- W4385406853 cites W2130326770 @default.
- W4385406853 cites W2131330057 @default.
- W4385406853 cites W2132594773 @default.
- W4385406853 cites W2133795831 @default.
- W4385406853 cites W2135217219 @default.
- W4385406853 cites W2137662702 @default.
- W4385406853 cites W2138226825 @default.
- W4385406853 cites W2138534354 @default.
- W4385406853 cites W2141065273 @default.
- W4385406853 cites W2150464859 @default.
- W4385406853 cites W2150709240 @default.
- W4385406853 cites W2157405334 @default.
- W4385406853 cites W2158031531 @default.
- W4385406853 cites W2158822657 @default.
- W4385406853 cites W2158849361 @default.
- W4385406853 cites W2160234571 @default.
- W4385406853 cites W2162344377 @default.
- W4385406853 cites W2171294019 @default.
- W4385406853 cites W2188846692 @default.
- W4385406853 cites W2189221254 @default.
- W4385406853 cites W2283809486 @default.
- W4385406853 cites W2323566388 @default.
- W4385406853 cites W2327628147 @default.
- W4385406853 cites W2332951586 @default.
- W4385406853 cites W2337454357 @default.
- W4385406853 cites W2384715846 @default.
- W4385406853 cites W2405977822 @default.
- W4385406853 cites W2531252525 @default.
- W4385406853 cites W2553809843 @default.
- W4385406853 cites W2582793111 @default.
- W4385406853 cites W2586360876 @default.
- W4385406853 cites W2616792756 @default.
- W4385406853 cites W2743200817 @default.
- W4385406853 cites W2743305150 @default.
- W4385406853 cites W2745151107 @default.
- W4385406853 cites W2749479110 @default.
- W4385406853 cites W2752336761 @default.
- W4385406853 cites W2890120255 @default.