FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385413233> ?p ?o ?g. }

• W4385413233 endingPage "e162" @default.
• W4385413233 startingPage "e151" @default.
• W4385413233 abstract "This study aimed to develop a liver metastasis-related gene prognostic index (LMPI) for pancreatic ductal adenocarcinoma prognosis and therapy.The Cancer Genome Atlas data set was used to identify liver metastasis-related hub genes via weighted gene coexpression network analysis. The core genes were identified to construct an LMPI by using the Cox regression method. An immune cell abundance identifier was applied to determine the immune cell abundance.A total of 78 hub liver metastasis-related genes in the black module were significantly enriched in complement and coagulation cascades, fat digestion and absorption, and the PPAR signaling pathway. Then, an LMPI was constructed on the basis of the 5 prognostic genes (MOGAT3, ASGR1, TRPM8, SGSM1, and LOC101927851). Patients with higher LMPI scores had poor overall survival, more co-occurring or mutually exclusive pairs of driver gene mutations, and less benefit from immunotherapy than patients with lower LMPI scores. In addition, a high correlation was also found between LMPI scores and immune infiltration, such as CD4 naive, CD8 T, cytotoxic T, T helper 2, follicular helper T, and natural killer cells.The core genes of the LMPI developed may be independent factors for predicting prognosis, immune characteristics, and immunotherapy efficacy in pancreatic ductal adenocarcinoma." @default.
• W4385413233 created "2023-08-01" @default.
• W4385413233 creator A5004392652 @default.
• W4385413233 creator A5005627824 @default.
• W4385413233 creator A5009088973 @default.
• W4385413233 creator A5009213665 @default.
• W4385413233 creator A5012324763 @default.
• W4385413233 creator A5025784292 @default.
• W4385413233 creator A5049322582 @default.
• W4385413233 creator A5070796699 @default.
• W4385413233 creator A5070820125 @default.
• W4385413233 creator A5080267086 @default.
• W4385413233 date "2023-02-01" @default.
• W4385413233 modified "2023-10-18" @default.
• W4385413233 title "Identifying Liver Metastasis-Related Genes Through a Coexpression Network to Construct a 5-Gene Model for Predicting Pancreatic Ductal Adenocarcinoma Patient Prognosis" @default.
• W4385413233 cites W1511590367 @default.
• W4385413233 cites W1966327575 @default.
• W4385413233 cites W1986273621 @default.
• W4385413233 cites W2050264923 @default.
• W4385413233 cites W2112595833 @default.
• W4385413233 cites W2175955272 @default.
• W4385413233 cites W2285093314 @default.
• W4385413233 cites W2322927469 @default.
• W4385413233 cites W2342236568 @default.
• W4385413233 cites W2417955877 @default.
• W4385413233 cites W2596418178 @default.
• W4385413233 cites W2602054361 @default.
• W4385413233 cites W2605073827 @default.
• W4385413233 cites W2605556350 @default.
• W4385413233 cites W2612467560 @default.
• W4385413233 cites W2767699537 @default.
• W4385413233 cites W2770516194 @default.
• W4385413233 cites W2774949562 @default.
• W4385413233 cites W2795645428 @default.
• W4385413233 cites W2884754721 @default.
• W4385413233 cites W2906384898 @default.
• W4385413233 cites W2928665623 @default.
• W4385413233 cites W2999417355 @default.
• W4385413233 cites W3005889306 @default.
• W4385413233 cites W3016560393 @default.
• W4385413233 cites W3028953435 @default.
• W4385413233 cites W3094912610 @default.
• W4385413233 cites W3119764205 @default.
• W4385413233 cites W3120257419 @default.
• W4385413233 cites W3128290039 @default.
• W4385413233 cites W3159995035 @default.
• W4385413233 cites W3166411495 @default.
• W4385413233 cites W3185354749 @default.
• W4385413233 doi "https://doi.org/10.1097/mpa.0000000000002229" @default.
• W4385413233 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37523607" @default.
• W4385413233 hasPublicationYear "2023" @default.
• W4385413233 type Work @default.
• W4385413233 citedByCount "0" @default.
• W4385413233 crossrefType "journal-article" @default.
• W4385413233 hasAuthorship W4385413233A5004392652 @default.
• W4385413233 hasAuthorship W4385413233A5005627824 @default.
• W4385413233 hasAuthorship W4385413233A5009088973 @default.
• W4385413233 hasAuthorship W4385413233A5009213665 @default.
• W4385413233 hasAuthorship W4385413233A5012324763 @default.
• W4385413233 hasAuthorship W4385413233A5025784292 @default.
• W4385413233 hasAuthorship W4385413233A5049322582 @default.
• W4385413233 hasAuthorship W4385413233A5070796699 @default.
• W4385413233 hasAuthorship W4385413233A5070820125 @default.
• W4385413233 hasAuthorship W4385413233A5080267086 @default.
• W4385413233 hasConcept C104317684 @default.
• W4385413233 hasConcept C121608353 @default.
• W4385413233 hasConcept C126322002 @default.
• W4385413233 hasConcept C143998085 @default.
• W4385413233 hasConcept C203014093 @default.
• W4385413233 hasConcept C2777701055 @default.
• W4385413233 hasConcept C2779013556 @default.
• W4385413233 hasConcept C2780210213 @default.
• W4385413233 hasConcept C2781182431 @default.
• W4385413233 hasConcept C502942594 @default.
• W4385413233 hasConcept C54355233 @default.
• W4385413233 hasConcept C71924100 @default.
• W4385413233 hasConcept C86803240 @default.
• W4385413233 hasConcept C8891405 @default.
• W4385413233 hasConceptScore W4385413233C104317684 @default.
• W4385413233 hasConceptScore W4385413233C121608353 @default.
• W4385413233 hasConceptScore W4385413233C126322002 @default.
• W4385413233 hasConceptScore W4385413233C143998085 @default.
• W4385413233 hasConceptScore W4385413233C203014093 @default.
• W4385413233 hasConceptScore W4385413233C2777701055 @default.
• W4385413233 hasConceptScore W4385413233C2779013556 @default.
• W4385413233 hasConceptScore W4385413233C2780210213 @default.
• W4385413233 hasConceptScore W4385413233C2781182431 @default.
• W4385413233 hasConceptScore W4385413233C502942594 @default.
• W4385413233 hasConceptScore W4385413233C54355233 @default.
• W4385413233 hasConceptScore W4385413233C71924100 @default.
• W4385413233 hasConceptScore W4385413233C86803240 @default.
• W4385413233 hasConceptScore W4385413233C8891405 @default.
• W4385413233 hasIssue "2" @default.
• W4385413233 hasLocation W43854132331 @default.
• W4385413233 hasLocation W43854132332 @default.
• W4385413233 hasOpenAccess W4385413233 @default.
• W4385413233 hasPrimaryLocation W43854132331 @default.
• W4385413233 hasRelatedWork W1996150995 @default.

• next