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• W4385431441 endingPage "100711" @default.
• W4385431441 startingPage "100711" @default.
• W4385431441 abstract "Infectious disease causes significant mortality in wild and farmed systems, threatening biodiversity, conservation and animal welfare, as well as food security. To mitigate impacts and inform policy, tools such as mathematical models and computer simulations are valuable for predicting the potential spread and impact of disease. This paper describes the development of the Aquaculture Disease Network Model, AquaNet-Mod, and demonstrates its application to evaluating disease epidemics and the efficacy of control, using a Viral Haemorrhagic Septicaemia (VHS) case study. AquaNet-Mod is a data-driven, stochastic, state-transition model. Disease spread can occur via four different mechanisms, i) live fish movement, ii) river based, iii) short distance mechanical and iv) distance independent mechanical. Sites transit between three disease states: susceptible, clinically infected and subclinically infected. Disease spread can be interrupted by the application of disease mitigation measures and controls such as contact tracing, culling, fallowing and surveillance. Results from a VHS case study highlight the potential for VHS to spread to 96% of sites over a 10 year time horizon if no disease controls are applied. Epidemiological impact was significantly reduced when live fish movement restrictions were placed on the most connected sites and further still, when disease controls, representative of current disease control policy in England and Wales, were applied. The importance of specific disease control measures, particularly contact tracing and disease detection rate, are also highlighted. The merit of this model for evaluation of disease spread and the efficacy of controls, in the context of policy, along with potential for further application and development of the model, for example to include economic parameters, is discussed." @default.
• W4385431441 created "2023-08-01" @default.
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• W4385431441 date "2023-09-01" @default.
• W4385431441 modified "2023-10-16" @default.
• W4385431441 title "The aquaculture disease network model (AquaNet-Mod): a simulation model to evaluate disease spread and controls for the salmonid industry in England and Wales" @default.
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• W4385431441 doi "https://doi.org/10.1016/j.epidem.2023.100711" @default.
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• W4385431441 hasPublicationYear "2023" @default.
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