Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385442240> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W4385442240 endingPage "13" @default.
- W4385442240 startingPage "205" @default.
- W4385442240 abstract "Given the association between cervicovaginal microbiota and OVC, we investigated the effect of Enterococcus faecium conditioned medium (CM) on OVC (Caov-4) cells.CM was obtained from the bacterium E. faecium isolated from the vagina of healthy women. The Caov-4 cells were treated with varying concentrations of CM that comprised co-cultured bacteria with 0.2, 0.5, 1, 1.5, and 2 OD for 12, 24, and 48 h. The apoptosis and growth of cancer cells were evaluated by 4′,6-diamidino-2-phenylindole (DAPI) staining, flow cytometry, and DNA laddering assay. Moreover, the expression of PTEN, BAX, BCL2, and AKT1 genes were analyzed using real-time PCR.The CM at a concentration of 0.5 OD from the cultured bacteria and incubation time of 48 h showed the highest negative effect on the viability of cancer cells. The CM treatment increased DNA fragmentation and also induced apoptosis in Caov-4 cells. Interestingly, CM could decrease the expression of proapoptotic genes were less, while antiapoptotic genes were more than fluorouracil in the presence of CM.CM of human-derived E. faecium could have an anticancer effect on OVC cells in a concentration- and time-dependent manner. This study demonstrated that E. faecium secretes anticancer substances into the CM, which could directly affect the viability and apoptosis of cancer cells." @default.
- W4385442240 created "2023-08-02" @default.
- W4385442240 creator A5007346416 @default.
- W4385442240 creator A5022749279 @default.
- W4385442240 creator A5056683050 @default.
- W4385442240 creator A5057473522 @default.
- W4385442240 creator A5074025214 @default.
- W4385442240 creator A5078375683 @default.
- W4385442240 creator A5090703780 @default.
- W4385442240 date "2023-07-01" @default.
- W4385442240 modified "2023-09-27" @default.
- W4385442240 title "Anticancer Effect of Enterococcus faecium, Isolated from Vaginal Fluid, on Ovarian Cancer Cells" @default.
- W4385442240 cites W2011411415 @default.
- W4385442240 cites W2036032294 @default.
- W4385442240 cites W2044825893 @default.
- W4385442240 cites W2059942373 @default.
- W4385442240 cites W2100816639 @default.
- W4385442240 cites W2112657305 @default.
- W4385442240 cites W2471290930 @default.
- W4385442240 cites W2529923829 @default.
- W4385442240 cites W2554224304 @default.
- W4385442240 cites W2617691583 @default.
- W4385442240 cites W2792724983 @default.
- W4385442240 cites W2801289705 @default.
- W4385442240 cites W2801847252 @default.
- W4385442240 cites W2801909255 @default.
- W4385442240 cites W2807649309 @default.
- W4385442240 cites W2884367937 @default.
- W4385442240 cites W2888758999 @default.
- W4385442240 cites W2901873507 @default.
- W4385442240 cites W2942591360 @default.
- W4385442240 cites W2956540509 @default.
- W4385442240 cites W3004563652 @default.
- W4385442240 cites W3011482979 @default.
- W4385442240 cites W3122254526 @default.
- W4385442240 cites W4224267469 @default.
- W4385442240 cites W4376612436 @default.
- W4385442240 doi "https://doi.org/10.52547/ibj.3846" @default.
- W4385442240 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37525437" @default.
- W4385442240 hasPublicationYear "2023" @default.
- W4385442240 type Work @default.
- W4385442240 citedByCount "0" @default.
- W4385442240 crossrefType "journal-article" @default.
- W4385442240 hasAuthorship W4385442240A5007346416 @default.
- W4385442240 hasAuthorship W4385442240A5022749279 @default.
- W4385442240 hasAuthorship W4385442240A5056683050 @default.
- W4385442240 hasAuthorship W4385442240A5057473522 @default.
- W4385442240 hasAuthorship W4385442240A5074025214 @default.
- W4385442240 hasAuthorship W4385442240A5078375683 @default.
- W4385442240 hasAuthorship W4385442240A5090703780 @default.
- W4385442240 hasConcept C153911025 @default.
- W4385442240 hasConcept C155878803 @default.
- W4385442240 hasConcept C185592680 @default.
- W4385442240 hasConcept C190283241 @default.
- W4385442240 hasConcept C2777527632 @default.
- W4385442240 hasConcept C2777677444 @default.
- W4385442240 hasConcept C31573885 @default.
- W4385442240 hasConcept C43759708 @default.
- W4385442240 hasConcept C523546767 @default.
- W4385442240 hasConcept C53227056 @default.
- W4385442240 hasConcept C54355233 @default.
- W4385442240 hasConcept C553184892 @default.
- W4385442240 hasConcept C55493867 @default.
- W4385442240 hasConcept C86803240 @default.
- W4385442240 hasConcept C89423630 @default.
- W4385442240 hasConceptScore W4385442240C153911025 @default.
- W4385442240 hasConceptScore W4385442240C155878803 @default.
- W4385442240 hasConceptScore W4385442240C185592680 @default.
- W4385442240 hasConceptScore W4385442240C190283241 @default.
- W4385442240 hasConceptScore W4385442240C2777527632 @default.
- W4385442240 hasConceptScore W4385442240C2777677444 @default.
- W4385442240 hasConceptScore W4385442240C31573885 @default.
- W4385442240 hasConceptScore W4385442240C43759708 @default.
- W4385442240 hasConceptScore W4385442240C523546767 @default.
- W4385442240 hasConceptScore W4385442240C53227056 @default.
- W4385442240 hasConceptScore W4385442240C54355233 @default.
- W4385442240 hasConceptScore W4385442240C553184892 @default.
- W4385442240 hasConceptScore W4385442240C55493867 @default.
- W4385442240 hasConceptScore W4385442240C86803240 @default.
- W4385442240 hasConceptScore W4385442240C89423630 @default.
- W4385442240 hasIssue "4" @default.
- W4385442240 hasLocation W43854422401 @default.
- W4385442240 hasOpenAccess W4385442240 @default.
- W4385442240 hasPrimaryLocation W43854422401 @default.
- W4385442240 hasRelatedWork W1511425935 @default.
- W4385442240 hasRelatedWork W1756125747 @default.
- W4385442240 hasRelatedWork W1998025034 @default.
- W4385442240 hasRelatedWork W2031129247 @default.
- W4385442240 hasRelatedWork W2065628698 @default.
- W4385442240 hasRelatedWork W2082390138 @default.
- W4385442240 hasRelatedWork W2355227395 @default.
- W4385442240 hasRelatedWork W2379353544 @default.
- W4385442240 hasRelatedWork W2410730100 @default.
- W4385442240 hasRelatedWork W4385442240 @default.
- W4385442240 hasVolume "27" @default.
- W4385442240 isParatext "false" @default.
- W4385442240 isRetracted "false" @default.
- W4385442240 workType "article" @default.