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- W4385442819 abstract "Backgrounds More than half of the patients with bipolar disorder (BD) had depressive episodes at the onset of BD. Despite some suggested clinical predictors, there are no certain criteria for predicting which unipolar depression patient switch to manic episodes during the treatment course. Electrophysiological markers can address this issue. Methods Pretreatment quantitative electroencephalography (qEEG) records of patients diagnosed with major depressive disorder (MDD) or BD at the first visit were included in the study. Patients with MDD were also grouped with manic switch (MS) or MDD based on the diagnosis of later visits. The qEEG spectral power was analyzed across 3 groups, that is, MS, MDD, and BD. Results Compared to patients whose diagnosis did not change, patients with MS had accelerated high-frequency activities predominantly in the left hemisphere (central-parietal-occipital regions). In contrast, they showed increased slow wave activity predominantly in the right hemisphere (parietal-occipital regions). Conclusion It can be concluded that searching for electrophysiological markers, which have distinct advantages of repeatability, noninvasiveness, and cost-effectiveness, can facilitate the prediction of the MS." @default.
- W4385442819 created "2023-08-02" @default.
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- W4385442819 date "2023-07-31" @default.
- W4385442819 modified "2023-09-27" @default.
- W4385442819 title "Predictive Value of qEEG in Manic Switch of Depressed Patients" @default.
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- W4385442819 doi "https://doi.org/10.1177/15500594231190278" @default.
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- W4385442819 hasPublicationYear "2023" @default.
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