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• W4385476922 abstract "Lymph node metastasis is a frequent occurrence in a variety of tumour forms and poses an enormous challenge to cancer treatment. This process is critical to the development of the disease and is frequently linked to a poor prognosis. Over 90% of cancerous cells move through lymph nodes, making them important entry routes for the spread of cancer cells. The prognosis of cancer patients is significantly impacted by lymph node metastases, which also affects treatment choices. Targeting lymph node metastases presents numerous difficulties for conventional medication delivery techniques. It is still very difficult to selectively target cancer cells in lymph nodes without risking injury to healthy organs and unforeseen consequences. Additionally, systemic delivery of drugs is hampered by the slow flow rate of lymphatic vessels. Chemotherapeutic medicines' poor solubility and stability further reduce their effectiveness when taken orally. Additionally, the extracellular matrix that surrounds lymph node tumours is extensive, which makes it difficult for conventional pharmaceutical delivery systems to reach cancer cells. The development of nanocarriers for precise drug delivery to LNs has attracted a lot of interest to overcome these obstacles. Most solid tumours first spread through the lymphatic system, hence effective drug administration to these tissues is essential for better therapeutic results. Nanocarriers have several benefits, including the capacity to pass through barriers like blood-brain barriers and membranes to reach the lymphatic system. High medication dosages can be enclosed thanks to the physicochemical characteristics of nanocarriers, such as their higher surface-to-volume ratio. Additionally, ligands, antibodies, polymers, or biological molecules can be attached to nanocarrier surfaces to change their properties, allowing for the targeted delivery of lymph node epithelial cells. This use of nanocarriers for drug delivery maximizes on-target effects and related adverse effects while improving the effectiveness of medication delivery to target locations. More research and development in this field is needed to optimize nanocarrier design, increase targeting capabilities, and expand clinical applications for better cancer care." @default.
• W4385476922 created "2023-08-03" @default.
• W4385476922 creator A5006627921 @default.
• W4385476922 creator A5009059275 @default.
• W4385476922 creator A5009093556 @default.
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• W4385476922 creator A5061297324 @default.
• W4385476922 creator A5069590869 @default.
• W4385476922 creator A5086442555 @default.
• W4385476922 date "2023-08-02" @default.
• W4385476922 modified "2023-10-16" @default.
• W4385476922 title "Multifunctional nanocarriers for targeted drug delivery and diagnostic applications of lymph nodes metastasis: a review of recent trends and future perspectives" @default.
• W4385476922 cites W132820133 @default.
• W4385476922 cites W1871308790 @default.
• W4385476922 cites W1939151472 @default.
• W4385476922 cites W1970238011 @default.
• W4385476922 cites W1970266024 @default.
• W4385476922 cites W1972582749 @default.
• W4385476922 cites W1976104973 @default.
• W4385476922 cites W1981217078 @default.
• W4385476922 cites W1981638413 @default.
• W4385476922 cites W1983259978 @default.
• W4385476922 cites W1988333177 @default.
• W4385476922 cites W1988494943 @default.
• W4385476922 cites W1989680746 @default.
• W4385476922 cites W1990295693 @default.
• W4385476922 cites W1991626424 @default.
• W4385476922 cites W1993752154 @default.
• W4385476922 cites W1994535712 @default.
• W4385476922 cites W1996917548 @default.
• W4385476922 cites W1998472187 @default.
• W4385476922 cites W2001498530 @default.
• W4385476922 cites W2012693333 @default.
• W4385476922 cites W2016054079 @default.
• W4385476922 cites W2016614248 @default.
• W4385476922 cites W2030112212 @default.
• W4385476922 cites W2030837990 @default.
• W4385476922 cites W2032760352 @default.
• W4385476922 cites W2034750640 @default.
• W4385476922 cites W2039486450 @default.
• W4385476922 cites W2042621950 @default.
• W4385476922 cites W2045961469 @default.
• W4385476922 cites W2050252713 @default.
• W4385476922 cites W2051034864 @default.
• W4385476922 cites W2057798678 @default.
• W4385476922 cites W2060634714 @default.
• W4385476922 cites W2060876615 @default.
• W4385476922 cites W2063508230 @default.
• W4385476922 cites W2073171012 @default.
• W4385476922 cites W2075649241 @default.
• W4385476922 cites W2076261339 @default.
• W4385476922 cites W2079142824 @default.
• W4385476922 cites W2081255855 @default.
• W4385476922 cites W2081862607 @default.
• W4385476922 cites W2082587127 @default.
• W4385476922 cites W2100356714 @default.
• W4385476922 cites W2103468798 @default.
• W4385476922 cites W2104558356 @default.
• W4385476922 cites W2106530202 @default.
• W4385476922 cites W2110643416 @default.
• W4385476922 cites W2114245966 @default.
• W4385476922 cites W2116810900 @default.
• W4385476922 cites W2122418437 @default.
• W4385476922 cites W2123920496 @default.
• W4385476922 cites W2125071715 @default.
• W4385476922 cites W2137605518 @default.
• W4385476922 cites W2138944326 @default.
• W4385476922 cites W2140172368 @default.
• W4385476922 cites W2140181820 @default.
• W4385476922 cites W2140568284 @default.
• W4385476922 cites W2147626413 @default.
• W4385476922 cites W2149163652 @default.
• W4385476922 cites W2161331122 @default.
• W4385476922 cites W2166328120 @default.
• W4385476922 cites W2168628444 @default.
• W4385476922 cites W2283047478 @default.
• W4385476922 cites W2285881370 @default.
• W4385476922 cites W2292627006 @default.
• W4385476922 cites W2316408327 @default.
• W4385476922 cites W2316532651 @default.
• W4385476922 cites W2322861634 @default.
• W4385476922 cites W2336353704 @default.
• W4385476922 cites W2399245139 @default.
• W4385476922 cites W2414292574 @default.
• W4385476922 cites W2520390708 @default.
• W4385476922 cites W2524853437 @default.
• W4385476922 cites W2555150119 @default.
• W4385476922 cites W2594430330 @default.
• W4385476922 cites W2599741499 @default.
• W4385476922 cites W2604409111 @default.
• W4385476922 cites W2749726749 @default.
• W4385476922 cites W2761331279 @default.
• W4385476922 cites W2770084469 @default.
• W4385476922 cites W2787117586 @default.
• W4385476922 cites W2790347249 @default.
• W4385476922 cites W2791899207 @default.
• W4385476922 cites W2887782980 @default.
• W4385476922 cites W2895925444 @default.
• W4385476922 cites W2898415565 @default.

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