FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385482816> ?p ?o ?g. }

• W4385482816 endingPage "e18887" @default.
• W4385482816 startingPage "e18887" @default.
• W4385482816 abstract "<h2>Abstract</h2><h3>Background</h3> Leptin, adiponectin and its ratio (L/A), as well as adipocyte fatty acid binding protein (A-FABP) have shown association to type 2 diabetes and atherosclerosis. Since first degree relatives (FDR) of type 2 diabetes are known to have higher risks of developing aforementioned diseases, this study aimed to see differences in adipokines profiles between FDR of type 2 diabetes and non-FDR counterpart. <h3>Methods</h3> Age, sex and body mass index (BMI)-matched normotensive-normoglycemic subjects, aged 19–39 years with BMI<30 kg/m², were included in this cross-sectional study. Serum adiponectin, leptin, and A-FABP levels were measured by sandwich ELISA while HOMA-IR was calculated from fasting blood glucose and insulin levels. <h3>Results</h3> Of 116 subjects recruited, there were significant difference of insulin level (6.00 vs 5.00 μIU/mL, <i>P</i> = 0.029) and HOMA-IR (1.27 vs 1.10, <i>P</i> = 0.028). Adiponectin, leptin, L/A ratio, and A-FABP levels were not statistically different between FDR and non-FDR groups. Stratified by BMI, non-obese FDR had higher L/A ratio (0.83 vs 0.49, <i>P</i> = 0.020) compared to those of corresponding non-FDR. In multivariate analysis, after adjusting for age, sex, waist circumference, BMI, and metabolic profiles (HbA1C, HOMA-IR, LDL-C, HDL-C, and triglyceride levels), FDR status became significantly associated with adiponectin level, and in non-obese subgroup, remained its significance with L/A ratio. <h3>Conclusion</h3> The FDR status was independently associated with adiponectin level. Furthermore, higher L/A ratio was more pronounced in non-obese FDR than those of non-FDR subjects, suggesting that FDR status may already contribute to the development of adipokines dysregulation before obesity occurs." @default.
• W4385482816 created "2023-08-03" @default.
• W4385482816 creator A5004245114 @default.
• W4385482816 creator A5005334952 @default.
• W4385482816 creator A5025902325 @default.
• W4385482816 creator A5065945549 @default.
• W4385482816 creator A5074731889 @default.
• W4385482816 creator A5076359959 @default.
• W4385482816 date "2023-08-01" @default.
• W4385482816 modified "2023-10-07" @default.
• W4385482816 title "Dysregulation of adipokines levels among healthy first-degree relatives of type 2 diabetes patients" @default.
• W4385482816 cites W1966717738 @default.
• W4385482816 cites W1974600155 @default.
• W4385482816 cites W1977720079 @default.
• W4385482816 cites W1987120082 @default.
• W4385482816 cites W1987917098 @default.
• W4385482816 cites W1991550867 @default.
• W4385482816 cites W2007026767 @default.
• W4385482816 cites W2018939673 @default.
• W4385482816 cites W2027670788 @default.
• W4385482816 cites W2029409909 @default.
• W4385482816 cites W2039680101 @default.
• W4385482816 cites W2056289375 @default.
• W4385482816 cites W2074205232 @default.
• W4385482816 cites W2083683145 @default.
• W4385482816 cites W2112161110 @default.
• W4385482816 cites W2113570079 @default.
• W4385482816 cites W2114416343 @default.
• W4385482816 cites W2120008076 @default.
• W4385482816 cites W2124275445 @default.
• W4385482816 cites W2127874189 @default.
• W4385482816 cites W2138102988 @default.
• W4385482816 cites W2148155549 @default.
• W4385482816 cites W2321082256 @default.
• W4385482816 cites W2353646670 @default.
• W4385482816 cites W2361659253 @default.
• W4385482816 cites W2515177180 @default.
• W4385482816 cites W2530142004 @default.
• W4385482816 cites W2760470116 @default.
• W4385482816 cites W2890161022 @default.
• W4385482816 cites W2907737333 @default.
• W4385482816 cites W2914390923 @default.
• W4385482816 cites W3011530329 @default.
• W4385482816 cites W3045728416 @default.
• W4385482816 cites W44929223 @default.
• W4385482816 doi "https://doi.org/10.1016/j.heliyon.2023.e18887" @default.
• W4385482816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37593625" @default.
• W4385482816 hasPublicationYear "2023" @default.
• W4385482816 type Work @default.
• W4385482816 citedByCount "0" @default.
• W4385482816 crossrefType "journal-article" @default.
• W4385482816 hasAuthorship W4385482816A5004245114 @default.
• W4385482816 hasAuthorship W4385482816A5005334952 @default.
• W4385482816 hasAuthorship W4385482816A5025902325 @default.
• W4385482816 hasAuthorship W4385482816A5065945549 @default.
• W4385482816 hasAuthorship W4385482816A5074731889 @default.
• W4385482816 hasAuthorship W4385482816A5076359959 @default.
• W4385482816 hasBestOaLocation W43854828161 @default.
• W4385482816 hasConcept C126322002 @default.
• W4385482816 hasConcept C134018914 @default.
• W4385482816 hasConcept C194832188 @default.
• W4385482816 hasConcept C2776193436 @default.
• W4385482816 hasConcept C2776782570 @default.
• W4385482816 hasConcept C2777180221 @default.
• W4385482816 hasConcept C2777391703 @default.
• W4385482816 hasConcept C2778163477 @default.
• W4385482816 hasConcept C2778913445 @default.
• W4385482816 hasConcept C2779862289 @default.
• W4385482816 hasConcept C2780221984 @default.
• W4385482816 hasConcept C2780578515 @default.
• W4385482816 hasConcept C2780613262 @default.
• W4385482816 hasConcept C2781179581 @default.
• W4385482816 hasConcept C511355011 @default.
• W4385482816 hasConcept C555293320 @default.
• W4385482816 hasConcept C71924100 @default.
• W4385482816 hasConceptScore W4385482816C126322002 @default.
• W4385482816 hasConceptScore W4385482816C134018914 @default.
• W4385482816 hasConceptScore W4385482816C194832188 @default.
• W4385482816 hasConceptScore W4385482816C2776193436 @default.
• W4385482816 hasConceptScore W4385482816C2776782570 @default.
• W4385482816 hasConceptScore W4385482816C2777180221 @default.
• W4385482816 hasConceptScore W4385482816C2777391703 @default.
• W4385482816 hasConceptScore W4385482816C2778163477 @default.
• W4385482816 hasConceptScore W4385482816C2778913445 @default.
• W4385482816 hasConceptScore W4385482816C2779862289 @default.
• W4385482816 hasConceptScore W4385482816C2780221984 @default.
• W4385482816 hasConceptScore W4385482816C2780578515 @default.
• W4385482816 hasConceptScore W4385482816C2780613262 @default.
• W4385482816 hasConceptScore W4385482816C2781179581 @default.
• W4385482816 hasConceptScore W4385482816C511355011 @default.
• W4385482816 hasConceptScore W4385482816C555293320 @default.
• W4385482816 hasConceptScore W4385482816C71924100 @default.
• W4385482816 hasFunder F4320319804 @default.
• W4385482816 hasFunder F4320325829 @default.
• W4385482816 hasFunder F4320326442 @default.
• W4385482816 hasIssue "8" @default.
• W4385482816 hasLocation W43854828161 @default.
• W4385482816 hasLocation W43854828162 @default.

• next