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• W4385490908 abstract "Data on cardiogenic shock in adults with congenital heart disease (ACHD) are scarce. We sought to describe cardiogenic shock in ACHD patients in a nationwide cardiogenic shock registry. From the multicentric FRENSHOCK registry (772 patients with cardiogenic shock from 49 French centres between April and October 2016), ACHD patients were compared with adults without congenital heart disease (non-ACHD). The primary outcome was defined by all-cause mortality, chronic ventricular assist device or heart transplantation at 1 year. Out of the 772 patients, seven (0.9%) were ACHD, who were younger (median age: 56 vs. 67 years), had fewer cardiovascular risk factors, such as hypertension (14.3% vs. 47.5%) and diabetes (14.3% vs. 28.3%), and no previous ischaemic cardiopathy (0 vs. 61.5%). Right heart catheterization (57.1% vs. 15.4%), pacemakers (28.6% vs. 4.6%) and implantable cardioverter-defibrillators (28.6% vs. 4.8%) were indicated more frequently in the management of ACHD patients compared with non-ACHD patients, whereas temporary mechanical circulatory support (0 vs. 18.7%) and invasive mechanical ventilation (14.3% vs. 38.1%) were less likely to be used in ACHD patients. At 1 year, the primary outcome occurred in 85.7% (95% confidence interval: 42.1–99.6) ACHD patients and 52.3% (95% confidence interval: 48.7–55.9) non-ACHD patients. Although 1-year mortality was not significantly different between ACHD patients (42.9%) and non-ACHD patients (45.4%), ventricular assist devices and heart transplantation tended to be more frequent in the ACHD group. Cardiogenic shock in ACHD patients is rare, accounting for only 0.9% of an unselected cardiogenic shock population. Despite being younger and having fewer co-morbidities, the prognosis of ACHD patients with cardiogenic shock remains severe, and is similar to that of other patients." @default.
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• W4385490908 date "2023-08-01" @default.
• W4385490908 modified "2023-10-18" @default.
• W4385490908 title "Cardiogenic shock in adults with congenital heart disease: Insights from the FRENSHOCK registry" @default.
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• W4385490908 doi "https://doi.org/10.1016/j.acvd.2023.06.008" @default.
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