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• W4385497773 endingPage "12352" @default.
• W4385497773 startingPage "12352" @default.
• W4385497773 abstract "Proper brain development essentially depends on the timed availability of sufficient amounts of thyroid hormone (TH). This, in turn, necessitates a tightly regulated expression of TH signaling components such as TH transporters, deiodinases, and TH receptors in a brain region- and cell-specific manner from early developmental stages onwards. Abnormal TH levels during critical stages, as well as mutations in TH signaling components that alter the global and/or local thyroidal state, result in detrimental consequences for brain development and neurological functions that involve alterations in central neurotransmitter systems. Thus, the question as to how TH signaling is implicated in the development and maturation of different neurotransmitter and neuromodulator systems has gained increasing attention. In this review, we first summarize the current knowledge on the regulation of TH signaling components during brain development. We then present recent advances in our understanding on how altered TH signaling compromises the development of cortical glutamatergic neurons, inhibitory GABAergic interneurons, cholinergic and dopaminergic neurons. Thereby, we highlight novel mechanistic insights and point out open questions in this evolving research field." @default.
• W4385497773 created "2023-08-03" @default.
• W4385497773 creator A5072704683 @default.
• W4385497773 creator A5084470346 @default.
• W4385497773 date "2023-08-02" @default.
• W4385497773 modified "2023-10-02" @default.
• W4385497773 title "Local Thyroid Hormone Action in Brain Development" @default.
• W4385497773 cites W1548473231 @default.
• W4385497773 cites W1592115964 @default.
• W4385497773 cites W1762915743 @default.
• W4385497773 cites W1924943590 @default.
• W4385497773 cites W1964580534 @default.
• W4385497773 cites W1965462646 @default.
• W4385497773 cites W1968162860 @default.
• W4385497773 cites W1969019749 @default.
• W4385497773 cites W1970648725 @default.
• W4385497773 cites W1972912923 @default.
• W4385497773 cites W1974563037 @default.
• W4385497773 cites W1975956491 @default.
• W4385497773 cites W1976648095 @default.
• W4385497773 cites W1977677577 @default.
• W4385497773 cites W1978086567 @default.
• W4385497773 cites W1979030149 @default.
• W4385497773 cites W1980049394 @default.
• W4385497773 cites W1981041844 @default.
• W4385497773 cites W1982018791 @default.
• W4385497773 cites W1982566905 @default.
• W4385497773 cites W1985645274 @default.
• W4385497773 cites W1987185095 @default.
• W4385497773 cites W1989898590 @default.
• W4385497773 cites W1990465508 @default.
• W4385497773 cites W1990498832 @default.
• W4385497773 cites W1992782297 @default.
• W4385497773 cites W1996321551 @default.
• W4385497773 cites W1997994432 @default.
• W4385497773 cites W2000163396 @default.
• W4385497773 cites W2002311807 @default.
• W4385497773 cites W2007034511 @default.
• W4385497773 cites W2013338106 @default.
• W4385497773 cites W2015473801 @default.
• W4385497773 cites W2018662956 @default.
• W4385497773 cites W2021747578 @default.
• W4385497773 cites W2021932599 @default.
• W4385497773 cites W2024009242 @default.
• W4385497773 cites W2028378639 @default.
• W4385497773 cites W2032036886 @default.
• W4385497773 cites W2032232458 @default.
• W4385497773 cites W2033067264 @default.
• W4385497773 cites W2036551744 @default.
• W4385497773 cites W2038346649 @default.
• W4385497773 cites W2041329238 @default.
• W4385497773 cites W2043019555 @default.
• W4385497773 cites W2043159700 @default.
• W4385497773 cites W2044332381 @default.
• W4385497773 cites W2045087560 @default.
• W4385497773 cites W2046037386 @default.
• W4385497773 cites W2046152275 @default.
• W4385497773 cites W2048824071 @default.
• W4385497773 cites W2049586534 @default.
• W4385497773 cites W2052530461 @default.
• W4385497773 cites W2055272377 @default.
• W4385497773 cites W2059894721 @default.
• W4385497773 cites W2061909097 @default.
• W4385497773 cites W2063595480 @default.
• W4385497773 cites W2065748069 @default.
• W4385497773 cites W2069003539 @default.
• W4385497773 cites W2071436714 @default.
• W4385497773 cites W2074907255 @default.
• W4385497773 cites W2083657371 @default.
• W4385497773 cites W2084135119 @default.
• W4385497773 cites W2085848059 @default.
• W4385497773 cites W2086430283 @default.
• W4385497773 cites W2087378023 @default.
• W4385497773 cites W2089184462 @default.
• W4385497773 cites W2090661065 @default.
• W4385497773 cites W2090877505 @default.
• W4385497773 cites W2091805482 @default.
• W4385497773 cites W2092671813 @default.
• W4385497773 cites W2094196804 @default.
• W4385497773 cites W2096656736 @default.
• W4385497773 cites W2097440306 @default.
• W4385497773 cites W2099952757 @default.
• W4385497773 cites W2103080150 @default.
• W4385497773 cites W2109678330 @default.
• W4385497773 cites W2115599658 @default.
• W4385497773 cites W2116353330 @default.
• W4385497773 cites W2116517439 @default.
• W4385497773 cites W2125326394 @default.
• W4385497773 cites W2127247367 @default.
• W4385497773 cites W2127616959 @default.
• W4385497773 cites W2133036415 @default.
• W4385497773 cites W2133684250 @default.
• W4385497773 cites W2138527530 @default.
• W4385497773 cites W2140408970 @default.
• W4385497773 cites W2141479055 @default.
• W4385497773 cites W2142650316 @default.
• W4385497773 cites W2142746886 @default.
• W4385497773 cites W2143149828 @default.

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