Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385504759> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4385504759 endingPage "106343" @default.
- W4385504759 startingPage "106343" @default.
- W4385504759 abstract "As one of the major components in the fungal cell wall, chitin is a polymer of β-1,4-linked N-acetylglucosamine. Chitinases are hydrolytic enzymes that break down glycosidic bonds in the chitin. The human fungal pathogen Candida albicans has three chitinase-encoding genes, CaCHT1, CaCHT2 and CaCHT3. The CaCHT4 gene encodes a protein with the glycoside hydrolase family GH18 domain, Glyco_18, which suggests that CaCht4 might be a chitinase. In the present study, we have cloned, expressed and purified the N-terminally His6-tagged CaCht4 protein from bacterial cells. Further biochemical characterization has shown that this recombinant CaCht4 protein shows both exochitinase (chitobiosidase) and endochitinase activities, but has no N-acetylglucosaminase activity. The optimal temperature for the exochitinase activity of CaCht4 is 55 °C. Taken together, these data support that the CaCHT4 gene encodes a chitinase. Our finding provides a basis for us to understand the biological functions of the CaCHT4 gene in C. albicans." @default.
- W4385504759 created "2023-08-03" @default.
- W4385504759 creator A5022032305 @default.
- W4385504759 creator A5029097523 @default.
- W4385504759 date "2023-11-01" @default.
- W4385504759 modified "2023-10-16" @default.
- W4385504759 title "Cloning and biochemical characterization of a recombinant chitinase encoded by the CHT4 gene from Candida albicans" @default.
- W4385504759 cites W1937476509 @default.
- W4385504759 cites W1968125229 @default.
- W4385504759 cites W1974526096 @default.
- W4385504759 cites W1983287577 @default.
- W4385504759 cites W1991341187 @default.
- W4385504759 cites W1995362265 @default.
- W4385504759 cites W2012991384 @default.
- W4385504759 cites W2019352808 @default.
- W4385504759 cites W2030645447 @default.
- W4385504759 cites W2056642830 @default.
- W4385504759 cites W2062428389 @default.
- W4385504759 cites W2075471766 @default.
- W4385504759 cites W2078127945 @default.
- W4385504759 cites W2110492547 @default.
- W4385504759 cites W2122300369 @default.
- W4385504759 cites W2301877115 @default.
- W4385504759 cites W2330288859 @default.
- W4385504759 cites W2403188604 @default.
- W4385504759 cites W2790112671 @default.
- W4385504759 cites W2809902034 @default.
- W4385504759 cites W2917402352 @default.
- W4385504759 cites W2946559558 @default.
- W4385504759 cites W2990471894 @default.
- W4385504759 cites W3002763297 @default.
- W4385504759 cites W4283821741 @default.
- W4385504759 cites W4306878780 @default.
- W4385504759 doi "https://doi.org/10.1016/j.pep.2023.106343" @default.
- W4385504759 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37536579" @default.
- W4385504759 hasPublicationYear "2023" @default.
- W4385504759 type Work @default.
- W4385504759 citedByCount "0" @default.
- W4385504759 crossrefType "journal-article" @default.
- W4385504759 hasAuthorship W4385504759A5022032305 @default.
- W4385504759 hasAuthorship W4385504759A5029097523 @default.
- W4385504759 hasConcept C104317684 @default.
- W4385504759 hasConcept C121050878 @default.
- W4385504759 hasConcept C167625842 @default.
- W4385504759 hasConcept C196032511 @default.
- W4385504759 hasConcept C19924922 @default.
- W4385504759 hasConcept C199360897 @default.
- W4385504759 hasConcept C2779732960 @default.
- W4385504759 hasConcept C2780778831 @default.
- W4385504759 hasConcept C2780917455 @default.
- W4385504759 hasConcept C2781088250 @default.
- W4385504759 hasConcept C40767141 @default.
- W4385504759 hasConcept C41008148 @default.
- W4385504759 hasConcept C55493867 @default.
- W4385504759 hasConcept C86803240 @default.
- W4385504759 hasConcept C89423630 @default.
- W4385504759 hasConceptScore W4385504759C104317684 @default.
- W4385504759 hasConceptScore W4385504759C121050878 @default.
- W4385504759 hasConceptScore W4385504759C167625842 @default.
- W4385504759 hasConceptScore W4385504759C196032511 @default.
- W4385504759 hasConceptScore W4385504759C19924922 @default.
- W4385504759 hasConceptScore W4385504759C199360897 @default.
- W4385504759 hasConceptScore W4385504759C2779732960 @default.
- W4385504759 hasConceptScore W4385504759C2780778831 @default.
- W4385504759 hasConceptScore W4385504759C2780917455 @default.
- W4385504759 hasConceptScore W4385504759C2781088250 @default.
- W4385504759 hasConceptScore W4385504759C40767141 @default.
- W4385504759 hasConceptScore W4385504759C41008148 @default.
- W4385504759 hasConceptScore W4385504759C55493867 @default.
- W4385504759 hasConceptScore W4385504759C86803240 @default.
- W4385504759 hasConceptScore W4385504759C89423630 @default.
- W4385504759 hasLocation W43855047591 @default.
- W4385504759 hasLocation W43855047592 @default.
- W4385504759 hasOpenAccess W4385504759 @default.
- W4385504759 hasPrimaryLocation W43855047591 @default.
- W4385504759 hasRelatedWork W2161396640 @default.
- W4385504759 hasRelatedWork W2384105220 @default.
- W4385504759 hasRelatedWork W2782431257 @default.
- W4385504759 hasRelatedWork W2784147177 @default.
- W4385504759 hasRelatedWork W2969689143 @default.
- W4385504759 hasRelatedWork W3025333918 @default.
- W4385504759 hasRelatedWork W3211670653 @default.
- W4385504759 hasRelatedWork W4213432104 @default.
- W4385504759 hasRelatedWork W4385504759 @default.
- W4385504759 hasRelatedWork W2243649573 @default.
- W4385504759 hasVolume "211" @default.
- W4385504759 isParatext "false" @default.
- W4385504759 isRetracted "false" @default.
- W4385504759 workType "article" @default.