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• W4385507907 abstract "A C6' bulky substituted quinine-catalyzed SNV reaction between 3-substituted oxindole and (E)-3-(nitromethylene)-oxindole was developed. This enantioselective C(sp3)-C(sp2) coupling furnished bisoxindole scaffolds featuring a vinyl-substituted all-carbon quaternary stereocenter with high stereoselectivities. In addition, the gram-scale synthesis and synthetic post-transformations were conducted to demonstrate the potential synthetic usefulness." @default.
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• W4385507907 date "2023-08-03" @default.
• W4385507907 modified "2023-10-17" @default.
• W4385507907 title "Enantioselective Nucleophilic Vinylic Substitution (S_NV) toward 3-Alkenyl-bisoxindoles Facilitated by C6′ Steric Bulk of Cinchona Alkaloid" @default.
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• W4385507907 doi "https://doi.org/10.1021/acs.orglett.3c01964" @default.
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