FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385514215> ?p ?o ?g. }

• W4385514215 endingPage "515" @default.
• W4385514215 startingPage "502" @default.
• W4385514215 abstract "Due to the rising prevalence of metabolic disorders, including type 2 diabetes (T2DM), new prevention and treatment strategies are needed. The aim was to examine the effect of astaxanthin (AST) on the major regulatory metabolism pathway SIRT-MAPK and fatty acid (FA) profile of plasma in patients with T2DM. This clinical trial included 68 T2DM patients randomly assigned to receive 10 mg/day of oral AST (n = 34) or placebo (n = 33) for 12 weeks. The expression level of SIRT1, AMPK activity, and the level of fatty acids in the serum were examined. The results showed that AST could modify the serum levels of saturated fatty acids (SFA) and polyunsaturated fatty acids (PUFA), particularly that of Arachidonic acid, from 11.31±0.35 to 8.52±0.72 %. Also, AST increased the expression and activity levels of SIRT1 and AMPK, respectively. Pearson analysis also revealed a significant association between AMPK activity and Linoleic acid serum (LA) levels (~ -0.604, p~0.013). AST can modify the FA profile of plasma by inducing metabolizing cells to uptake them. Also, it can activate the SIRT-AMPK pathway related to metabolism regulation. See also Figure 1(Fig. 1)." @default.
• W4385514215 created "2023-08-04" @default.
• W4385514215 creator A5004088621 @default.
• W4385514215 creator A5023911567 @default.
• W4385514215 creator A5091709020 @default.
• W4385514215 date "2023-01-01" @default.
• W4385514215 modified "2023-09-23" @default.
• W4385514215 title "Astaxanthin improves fatty acid dysregulation in diabetes by controlling the AMPK-SIRT1 pathway." @default.
• W4385514215 cites W1532082124 @default.
• W4385514215 cites W1565527343 @default.
• W4385514215 cites W1578840576 @default.
• W4385514215 cites W1983437136 @default.
• W4385514215 cites W1983502873 @default.
• W4385514215 cites W2009922820 @default.
• W4385514215 cites W2016294119 @default.
• W4385514215 cites W2022267544 @default.
• W4385514215 cites W2031846075 @default.
• W4385514215 cites W2041973984 @default.
• W4385514215 cites W2049005145 @default.
• W4385514215 cites W2052347239 @default.
• W4385514215 cites W2059751934 @default.
• W4385514215 cites W2060878818 @default.
• W4385514215 cites W2060977160 @default.
• W4385514215 cites W2087710728 @default.
• W4385514215 cites W2124597675 @default.
• W4385514215 cites W2148391873 @default.
• W4385514215 cites W2168526937 @default.
• W4385514215 cites W2174118934 @default.
• W4385514215 cites W2335448897 @default.
• W4385514215 cites W2606264420 @default.
• W4385514215 cites W2885341903 @default.
• W4385514215 cites W2974634715 @default.
• W4385514215 cites W3004349582 @default.
• W4385514215 cites W3096532228 @default.
• W4385514215 cites W4200152981 @default.
• W4385514215 cites W4238714725 @default.
• W4385514215 doi "https://doi.org/10.17179/excli2023-6132" @default.
• W4385514215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37534224" @default.
• W4385514215 hasPublicationYear "2023" @default.
• W4385514215 type Work @default.
• W4385514215 citedByCount "0" @default.
• W4385514215 crossrefType "journal-article" @default.
• W4385514215 hasAuthorship W4385514215A5004088621 @default.
• W4385514215 hasAuthorship W4385514215A5023911567 @default.
• W4385514215 hasAuthorship W4385514215A5091709020 @default.
• W4385514215 hasConcept C126322002 @default.
• W4385514215 hasConcept C134018914 @default.
• W4385514215 hasConcept C142724271 @default.
• W4385514215 hasConcept C181199279 @default.
• W4385514215 hasConcept C185592680 @default.
• W4385514215 hasConcept C19038510 @default.
• W4385514215 hasConcept C204787440 @default.
• W4385514215 hasConcept C27081682 @default.
• W4385514215 hasConcept C2776991927 @default.
• W4385514215 hasConcept C2777180221 @default.
• W4385514215 hasConcept C2778078955 @default.
• W4385514215 hasConcept C2780124434 @default.
• W4385514215 hasConcept C2780809830 @default.
• W4385514215 hasConcept C4733338 @default.
• W4385514215 hasConcept C543025807 @default.
• W4385514215 hasConcept C55493867 @default.
• W4385514215 hasConcept C555293320 @default.
• W4385514215 hasConcept C62231903 @default.
• W4385514215 hasConcept C71924100 @default.
• W4385514215 hasConcept C97029542 @default.
• W4385514215 hasConceptScore W4385514215C126322002 @default.
• W4385514215 hasConceptScore W4385514215C134018914 @default.
• W4385514215 hasConceptScore W4385514215C142724271 @default.
• W4385514215 hasConceptScore W4385514215C181199279 @default.
• W4385514215 hasConceptScore W4385514215C185592680 @default.
• W4385514215 hasConceptScore W4385514215C19038510 @default.
• W4385514215 hasConceptScore W4385514215C204787440 @default.
• W4385514215 hasConceptScore W4385514215C27081682 @default.
• W4385514215 hasConceptScore W4385514215C2776991927 @default.
• W4385514215 hasConceptScore W4385514215C2777180221 @default.
• W4385514215 hasConceptScore W4385514215C2778078955 @default.
• W4385514215 hasConceptScore W4385514215C2780124434 @default.
• W4385514215 hasConceptScore W4385514215C2780809830 @default.
• W4385514215 hasConceptScore W4385514215C4733338 @default.
• W4385514215 hasConceptScore W4385514215C543025807 @default.
• W4385514215 hasConceptScore W4385514215C55493867 @default.
• W4385514215 hasConceptScore W4385514215C555293320 @default.
• W4385514215 hasConceptScore W4385514215C62231903 @default.
• W4385514215 hasConceptScore W4385514215C71924100 @default.
• W4385514215 hasConceptScore W4385514215C97029542 @default.
• W4385514215 hasLocation W43855142151 @default.
• W4385514215 hasOpenAccess W4385514215 @default.
• W4385514215 hasPrimaryLocation W43855142151 @default.
• W4385514215 hasRelatedWork W1496885974 @default.
• W4385514215 hasRelatedWork W1947776909 @default.
• W4385514215 hasRelatedWork W1974249541 @default.
• W4385514215 hasRelatedWork W1979589073 @default.
• W4385514215 hasRelatedWork W2004534398 @default.
• W4385514215 hasRelatedWork W2037992742 @default.
• W4385514215 hasRelatedWork W2041770204 @default.
• W4385514215 hasRelatedWork W2053687970 @default.
• W4385514215 hasRelatedWork W2115229762 @default.
• W4385514215 hasRelatedWork W2786826470 @default.

• next