FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385514294> ?p ?o ?g. }

• W4385514294 abstract "Summary Patients with multiple myeloma (MM) are at an elevated risk of venous thromboembolism (VTE), which is further increased for those undergoing anti‐myeloma therapy. Current guidelines suggest low‐dose direct oral anticoagulants (DOACs) as an alternative to aspirin for primary thromboprophylaxis in this population, but data comparing these two therapies are limited. We performed a systematic review and meta‐analysis to compare DOACs with aspirin for primary thromboprophylaxis in individuals undergoing outpatient anti‐myeloma therapy. Studies were selected when comparing DOACs versus aspirin for thrombotic and haemorrhagic outcomes. We included 10 randomised controlled trials and observational studies comprising 1026 patients with MM who received primary thromboprophylaxis with DOACs ( n = 337) or aspirin ( n = 689). DOAC thromboprophylaxis was associated with a significantly lower incidence of VTE compared with aspirin (OR 0.33; 95% CI 0.16–0.68; p < 0.001). Major, clinically relevant non‐major and minor bleeding event rates did not differ significantly between groups. Overall, our meta‐analysis suggests that DOACs may be a preferable option to aspirin for the prevention of MM‐related thrombosis. However, these results should be interpreted in the context of heterogeneous baseline population characteristics and potential bias from including observational studies. Further research is needed to evaluate the optimal thromboprophylaxis strategy, particularly in high‐risk individuals." @default.
• W4385514294 created "2023-08-04" @default.
• W4385514294 creator A5009316322 @default.
• W4385514294 creator A5033877515 @default.
• W4385514294 creator A5047805762 @default.
• W4385514294 creator A5055870392 @default.
• W4385514294 creator A5057570261 @default.
• W4385514294 creator A5064019698 @default.
• W4385514294 date "2023-08-02" @default.
• W4385514294 modified "2023-10-12" @default.
• W4385514294 title "Direct oral anticoagulants versus aspirin for primary thromboprophylaxis in patients with multiple myeloma undergoing outpatient therapy: A systematic review and updated <scp>meta‐analysis</scp>" @default.
• W4385514294 cites W1505239733 @default.
• W4385514294 cites W1975136159 @default.
• W4385514294 cites W2002125060 @default.
• W4385514294 cites W2023189333 @default.
• W4385514294 cites W2027190006 @default.
• W4385514294 cites W2072275120 @default.
• W4385514294 cites W2090171247 @default.
• W4385514294 cites W2097331346 @default.
• W4385514294 cites W2099772377 @default.
• W4385514294 cites W2132506384 @default.
• W4385514294 cites W2152124092 @default.
• W4385514294 cites W2162499932 @default.
• W4385514294 cites W2531269403 @default.
• W4385514294 cites W2549396793 @default.
• W4385514294 cites W2567188480 @default.
• W4385514294 cites W2775303056 @default.
• W4385514294 cites W2803510758 @default.
• W4385514294 cites W2902078827 @default.
• W4385514294 cites W2917722773 @default.
• W4385514294 cites W2948992765 @default.
• W4385514294 cites W2964299108 @default.
• W4385514294 cites W2970684805 @default.
• W4385514294 cites W2989714602 @default.
• W4385514294 cites W2999553182 @default.
• W4385514294 cites W3000291762 @default.
• W4385514294 cites W3021484626 @default.
• W4385514294 cites W3090209681 @default.
• W4385514294 cites W3100796456 @default.
• W4385514294 cites W3131837899 @default.
• W4385514294 cites W3144543375 @default.
• W4385514294 cites W3162275315 @default.
• W4385514294 cites W3195482708 @default.
• W4385514294 cites W3211521877 @default.
• W4385514294 cites W4214914414 @default.
• W4385514294 cites W4283397788 @default.
• W4385514294 cites W4286208236 @default.
• W4385514294 cites W4293217929 @default.
• W4385514294 cites W4296034616 @default.
• W4385514294 cites W4311137528 @default.
• W4385514294 cites W4312141188 @default.
• W4385514294 doi "https://doi.org/10.1111/bjh.19017" @default.
• W4385514294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37533165" @default.
• W4385514294 hasPublicationYear "2023" @default.
• W4385514294 type Work @default.
• W4385514294 citedByCount "1" @default.
• W4385514294 countsByYear W43855142942023 @default.
• W4385514294 crossrefType "journal-article" @default.
• W4385514294 hasAuthorship W4385514294A5009316322 @default.
• W4385514294 hasAuthorship W4385514294A5033877515 @default.
• W4385514294 hasAuthorship W4385514294A5047805762 @default.
• W4385514294 hasAuthorship W4385514294A5055870392 @default.
• W4385514294 hasAuthorship W4385514294A5057570261 @default.
• W4385514294 hasAuthorship W4385514294A5064019698 @default.
• W4385514294 hasBestOaLocation W43855142941 @default.
• W4385514294 hasConcept C126322002 @default.
• W4385514294 hasConcept C151730666 @default.
• W4385514294 hasConcept C168563851 @default.
• W4385514294 hasConcept C177713679 @default.
• W4385514294 hasConcept C23131810 @default.
• W4385514294 hasConcept C2777628954 @default.
• W4385514294 hasConcept C2779343474 @default.
• W4385514294 hasConcept C2908647359 @default.
• W4385514294 hasConcept C71924100 @default.
• W4385514294 hasConcept C86803240 @default.
• W4385514294 hasConcept C95190672 @default.
• W4385514294 hasConcept C99454951 @default.
• W4385514294 hasConceptScore W4385514294C126322002 @default.
• W4385514294 hasConceptScore W4385514294C151730666 @default.
• W4385514294 hasConceptScore W4385514294C168563851 @default.
• W4385514294 hasConceptScore W4385514294C177713679 @default.
• W4385514294 hasConceptScore W4385514294C23131810 @default.
• W4385514294 hasConceptScore W4385514294C2777628954 @default.
• W4385514294 hasConceptScore W4385514294C2779343474 @default.
• W4385514294 hasConceptScore W4385514294C2908647359 @default.
• W4385514294 hasConceptScore W4385514294C71924100 @default.
• W4385514294 hasConceptScore W4385514294C86803240 @default.
• W4385514294 hasConceptScore W4385514294C95190672 @default.
• W4385514294 hasConceptScore W4385514294C99454951 @default.
• W4385514294 hasLocation W43855142941 @default.
• W4385514294 hasLocation W43855142942 @default.
• W4385514294 hasOpenAccess W4385514294 @default.
• W4385514294 hasPrimaryLocation W43855142941 @default.
• W4385514294 hasRelatedWork W1967947002 @default.
• W4385514294 hasRelatedWork W2010490510 @default.
• W4385514294 hasRelatedWork W2019059391 @default.
• W4385514294 hasRelatedWork W2064286441 @default.
• W4385514294 hasRelatedWork W2332797319 @default.
• W4385514294 hasRelatedWork W2542248393 @default.
• W4385514294 hasRelatedWork W2612824725 @default.

• next