FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385514862> ?p ?o ?g. }

• W4385514862 abstract "ABSTRACT The regulation of the intracellular level of ATP is a fundamental aspect of bioenergetics. Actin cytoskeletal dynamics have been reported to be an energetic drain in developing neurons and platelets. We addressed the role of actin dynamics in primary embryonic chicken neurons using luciferase assays, and by measurement of the ATP/ADP ratio using the ratiometric reporter PercevalHR and the ATP level using the ratiometric reporter mRuby-iATPSnFR. None of the methods revealed an effect of suppressing actin dynamics on the decline in the neuronal ATP level or the ATP/ADP ratio following shutdown of ATP production. Similarly, we find that treatments that elevate or suppress actin dynamics do not alter the ATP/ADP ratio in growth cones, the subcellular domain with the highest actin dynamics in developing neurons. Collectively, the data indicate that actin cytoskeletal dynamics are not a significant energy drain in developing neurons and that the ATP/ADP ratio is maintained when energy utilization varies. Discrepancies between prior work and the current data are discussed with emphasis on methodology and interpretation of the data." @default.
• W4385514862 created "2023-08-04" @default.
• W4385514862 creator A5046042736 @default.
• W4385514862 creator A5075088638 @default.
• W4385514862 date "2023-08-15" @default.
• W4385514862 modified "2023-10-09" @default.
• W4385514862 title "Actin cytoskeletal dynamics do not impose an energy drain on growth cone bioenergetics" @default.
• W4385514862 cites W1510919372 @default.
• W4385514862 cites W1543755059 @default.
• W4385514862 cites W1560440125 @default.
• W4385514862 cites W1565979608 @default.
• W4385514862 cites W1592529377 @default.
• W4385514862 cites W1894865050 @default.
• W4385514862 cites W1967646152 @default.
• W4385514862 cites W1968344191 @default.
• W4385514862 cites W1970971912 @default.
• W4385514862 cites W1997797926 @default.
• W4385514862 cites W2004734800 @default.
• W4385514862 cites W2009682605 @default.
• W4385514862 cites W2016760704 @default.
• W4385514862 cites W2020583390 @default.
• W4385514862 cites W2023343693 @default.
• W4385514862 cites W2024662178 @default.
• W4385514862 cites W2027854877 @default.
• W4385514862 cites W2030113770 @default.
• W4385514862 cites W2030446659 @default.
• W4385514862 cites W2039071037 @default.
• W4385514862 cites W2053535390 @default.
• W4385514862 cites W2059514736 @default.
• W4385514862 cites W2062875886 @default.
• W4385514862 cites W2064005757 @default.
• W4385514862 cites W2065689693 @default.
• W4385514862 cites W2066129746 @default.
• W4385514862 cites W2071747777 @default.
• W4385514862 cites W2073611916 @default.
• W4385514862 cites W2082194777 @default.
• W4385514862 cites W2084495942 @default.
• W4385514862 cites W2105048641 @default.
• W4385514862 cites W2109433057 @default.
• W4385514862 cites W2126823064 @default.
• W4385514862 cites W2129762934 @default.
• W4385514862 cites W2139565721 @default.
• W4385514862 cites W2145482520 @default.
• W4385514862 cites W2368877988 @default.
• W4385514862 cites W2410902285 @default.
• W4385514862 cites W2554665819 @default.
• W4385514862 cites W2734000955 @default.
• W4385514862 cites W2761107294 @default.
• W4385514862 cites W2900803161 @default.
• W4385514862 cites W2904685632 @default.
• W4385514862 cites W2952574460 @default.
• W4385514862 cites W2961844889 @default.
• W4385514862 cites W2990326399 @default.
• W4385514862 cites W3047484848 @default.
• W4385514862 cites W3096787175 @default.
• W4385514862 cites W3126942531 @default.
• W4385514862 cites W3127051863 @default.
• W4385514862 cites W3153190939 @default.
• W4385514862 cites W3174860619 @default.
• W4385514862 cites W3203110148 @default.
• W4385514862 cites W3216029364 @default.
• W4385514862 cites W4225673492 @default.
• W4385514862 cites W4291279388 @default.
• W4385514862 cites W4304891832 @default.
• W4385514862 cites W4367396610 @default.
• W4385514862 doi "https://doi.org/10.1242/jcs.261356" @default.
• W4385514862 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37534394" @default.
• W4385514862 hasPublicationYear "2023" @default.
• W4385514862 type Work @default.
• W4385514862 citedByCount "0" @default.
• W4385514862 crossrefType "journal-article" @default.
• W4385514862 hasAuthorship W4385514862A5046042736 @default.
• W4385514862 hasAuthorship W4385514862A5075088638 @default.
• W4385514862 hasBestOaLocation W43855148621 @default.
• W4385514862 hasConcept C100206155 @default.
• W4385514862 hasConcept C12554922 @default.
• W4385514862 hasConcept C125705527 @default.
• W4385514862 hasConcept C142669718 @default.
• W4385514862 hasConcept C1491633281 @default.
• W4385514862 hasConcept C28859421 @default.
• W4385514862 hasConcept C2993400109 @default.
• W4385514862 hasConcept C55493867 @default.
• W4385514862 hasConcept C79879829 @default.
• W4385514862 hasConcept C86803240 @default.
• W4385514862 hasConcept C95444343 @default.
• W4385514862 hasConceptScore W4385514862C100206155 @default.
• W4385514862 hasConceptScore W4385514862C12554922 @default.
• W4385514862 hasConceptScore W4385514862C125705527 @default.
• W4385514862 hasConceptScore W4385514862C142669718 @default.
• W4385514862 hasConceptScore W4385514862C1491633281 @default.
• W4385514862 hasConceptScore W4385514862C28859421 @default.
• W4385514862 hasConceptScore W4385514862C2993400109 @default.
• W4385514862 hasConceptScore W4385514862C55493867 @default.
• W4385514862 hasConceptScore W4385514862C79879829 @default.
• W4385514862 hasConceptScore W4385514862C86803240 @default.
• W4385514862 hasConceptScore W4385514862C95444343 @default.
• W4385514862 hasFunder F4320332161 @default.
• W4385514862 hasIssue "16" @default.
• W4385514862 hasLocation W43855148621 @default.
• W4385514862 hasLocation W43855148622 @default.

• next