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- W4385544206 abstract "Tissue perfusion can be measured by arterial spin labeling and dynamic susceptibility contrast (DSC) method. However, these methods cannot be easily applied to mouse. Alternatively, a bolus of paramagnetic deoxyhemoglobin induced by transient hypoxia may be used as an endogenous blood pool contrast agent. Dynamic BOLD MRI with hypoxic challenge was adopted in mice. A stimulus duration was determined, and its impact to animal physiology was investigated. With corrected arterial input function, quantitative CBF and CBV were determined. Overall, we successfully developed a technique with BOLD MRI and transient hypoxia." @default.
- W4385544206 created "2023-08-04" @default.
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- W4385544206 date "2023-08-03" @default.
- W4385544206 modified "2023-09-27" @default.
- W4385544206 title "Development of perfusion technique with dynamic BOLD MRI and transient hypoxia in mouse" @default.
- W4385544206 doi "https://doi.org/10.58530/2022/0339" @default.
- W4385544206 hasPublicationYear "2023" @default.
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