Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385544225> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W4385544225 endingPage "5862" @default.
- W4385544225 startingPage "5862" @default.
- W4385544225 abstract "Bambusae caulis in Liquamen (BCL), which is extracted from heat-treated fresh bamboo stems, is a traditional herbal medicine widely used in Eastern countries. Recently, it has been reported to have anti-inflammatory and whitening effects. However, the protective effect of BCL on hepatocytes has not yet been elucidated. The present study aimed to determine whether BCL prevents oxidative stress induced by tert-butyl hydroperoxide (t-BHP) and exerts cytoprotective effects on hepatocytes. High-performance liquid chromatography and liquid chromatography with tandem mass spectroscopy were performed to analyze the type of polyphenols present in BCL. The activities of antioxidant enzymes and hepatocyte viability were assessed. The benzoic acid content was the highest among polyphenols present in BCL. Benzoic acid acts as a scavenger of free radicals, including reactive oxygen species. BCL increased the expression of antioxidant enzymes (glutamate-cysteine ligase and NADPH quinone dehydrogenase (1)) by activating nuclear factor erythroid 2-related factor 2 and reduced tBHP-induced cell death by inhibiting oxidative stress. BCL inhibited tBHP-induced phosphorylation of p38 and c-Jun N-terminal kinase but not that of extracellular signal-regulated kinase. In conclusion, BCL is a promising therapeutic candidate for treating oxidative-stress-induced hepatocyte damage." @default.
- W4385544225 created "2023-08-04" @default.
- W4385544225 creator A5021298635 @default.
- W4385544225 date "2023-08-03" @default.
- W4385544225 modified "2023-09-30" @default.
- W4385544225 title "Cytoprotective Effect of Bambusae caulis in Liquamen by Blocking Oxidative Stress in Hepatocytes" @default.
- W4385544225 cites W1592096682 @default.
- W4385544225 cites W1759872093 @default.
- W4385544225 cites W1995986855 @default.
- W4385544225 cites W2022453225 @default.
- W4385544225 cites W2029681755 @default.
- W4385544225 cites W2032151039 @default.
- W4385544225 cites W2037382204 @default.
- W4385544225 cites W2045283564 @default.
- W4385544225 cites W2073915407 @default.
- W4385544225 cites W2110075826 @default.
- W4385544225 cites W2218128633 @default.
- W4385544225 cites W2290255978 @default.
- W4385544225 cites W2401030213 @default.
- W4385544225 cites W2519786994 @default.
- W4385544225 cites W2577851679 @default.
- W4385544225 cites W2614425307 @default.
- W4385544225 cites W2761912472 @default.
- W4385544225 cites W2795360915 @default.
- W4385544225 cites W2804513967 @default.
- W4385544225 cites W2934007764 @default.
- W4385544225 cites W3013726226 @default.
- W4385544225 cites W3015784228 @default.
- W4385544225 cites W3047040772 @default.
- W4385544225 cites W3137878085 @default.
- W4385544225 cites W3148503912 @default.
- W4385544225 cites W3150709518 @default.
- W4385544225 cites W3202650008 @default.
- W4385544225 cites W3210316066 @default.
- W4385544225 cites W4205729478 @default.
- W4385544225 cites W4281662348 @default.
- W4385544225 cites W952491933 @default.
- W4385544225 doi "https://doi.org/10.3390/molecules28155862" @default.
- W4385544225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37570831" @default.
- W4385544225 hasPublicationYear "2023" @default.
- W4385544225 type Work @default.
- W4385544225 citedByCount "0" @default.
- W4385544225 crossrefType "journal-article" @default.
- W4385544225 hasAuthorship W4385544225A5021298635 @default.
- W4385544225 hasBestOaLocation W43855442251 @default.
- W4385544225 hasConcept C185592680 @default.
- W4385544225 hasConcept C202751555 @default.
- W4385544225 hasConcept C2776151105 @default.
- W4385544225 hasConcept C2776200302 @default.
- W4385544225 hasConcept C2778004101 @default.
- W4385544225 hasConcept C2778979269 @default.
- W4385544225 hasConcept C48349386 @default.
- W4385544225 hasConcept C55493867 @default.
- W4385544225 hasConcept C86803240 @default.
- W4385544225 hasConcept C98274493 @default.
- W4385544225 hasConceptScore W4385544225C185592680 @default.
- W4385544225 hasConceptScore W4385544225C202751555 @default.
- W4385544225 hasConceptScore W4385544225C2776151105 @default.
- W4385544225 hasConceptScore W4385544225C2776200302 @default.
- W4385544225 hasConceptScore W4385544225C2778004101 @default.
- W4385544225 hasConceptScore W4385544225C2778979269 @default.
- W4385544225 hasConceptScore W4385544225C48349386 @default.
- W4385544225 hasConceptScore W4385544225C55493867 @default.
- W4385544225 hasConceptScore W4385544225C86803240 @default.
- W4385544225 hasConceptScore W4385544225C98274493 @default.
- W4385544225 hasIssue "15" @default.
- W4385544225 hasLocation W43855442251 @default.
- W4385544225 hasLocation W43855442252 @default.
- W4385544225 hasOpenAccess W4385544225 @default.
- W4385544225 hasPrimaryLocation W43855442251 @default.
- W4385544225 hasRelatedWork W1443871574 @default.
- W4385544225 hasRelatedWork W1490540217 @default.
- W4385544225 hasRelatedWork W2241760478 @default.
- W4385544225 hasRelatedWork W2313463101 @default.
- W4385544225 hasRelatedWork W2368772701 @default.
- W4385544225 hasRelatedWork W2737873067 @default.
- W4385544225 hasRelatedWork W2791181644 @default.
- W4385544225 hasRelatedWork W3214998341 @default.
- W4385544225 hasRelatedWork W99063305 @default.
- W4385544225 hasRelatedWork W3031685627 @default.
- W4385544225 hasVolume "28" @default.
- W4385544225 isParatext "false" @default.
- W4385544225 isRetracted "false" @default.
- W4385544225 workType "article" @default.