Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385547805> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W4385547805 endingPage "163" @default.
- W4385547805 startingPage "163" @default.
- W4385547805 abstract "163 Background: Differentiated thyroid carcinoma (DTC) in children is known to be more aggressive than in adults. However, there are no cohort studies in Asia that have compared the presentation and long-term outcomes of pediatric DTC with adult DTC. In this study, we aimed to compare the clinical characteristics and outcomes of pediatric DTC with a comparison cohort of adult DTC patients. Methods: We reviewed the data of 46 pediatric DTC patients who underwent total thyroidectomy from January 1991 to December 2021, along with a comparison cohort of 350 adult DTC patients at our hospital. All patients received postoperative radioiodine therapy. Clinicopathologic features and surgical outcomes were analyzed retrospectively, and patients were stratified according to the American Thyroid Association (ATA) risk stratification system. Clinical outcomes were classified according to Dynamic Risk Stratification (DRS) at the end of follow-up. Results: Children with DTC had less common papillary thyroid carcinoma (80 vs. 93%) but had larger primary tumors, more multifocal disease, and more lymph node and distant metastasis at presentation compared to adults. Thus, at initial risk stratification, more children had intermediate-to-high risk (62 vs. 49%) than adults. At the end of follow-up, fewer children were classified as having excellent response (no evidence of disease) than adults (48 vs. 79%). Based on the ATA risk stratification system, a higher percentage of high-risk children had structural-persistent disease (60%) compared to high-risk adults (29%), and a lower percentage of low-risk children became no evidence of disease (76%) compared to low-risk adults (93%). Conclusions: Children with DTC present with more extensive disease and have worse outcomes compared to adults. The ATA initial risk stratification system can predict long-term outcomes in both children and adult DTC patients and guide personalized management and follow-up strategies." @default.
- W4385547805 created "2023-08-04" @default.
- W4385547805 creator A5072720451 @default.
- W4385547805 date "2023-08-01" @default.
- W4385547805 modified "2023-09-23" @default.
- W4385547805 title "Comparison of the initial presentation and long-term outcome of differentiated thyroid carcinoma (DTC) between children and adults: A single institution experience in Taiwan." @default.
- W4385547805 doi "https://doi.org/10.1200/go.2023.9.supplement_1.163" @default.
- W4385547805 hasPublicationYear "2023" @default.
- W4385547805 type Work @default.
- W4385547805 citedByCount "0" @default.
- W4385547805 crossrefType "journal-article" @default.
- W4385547805 hasAuthorship W4385547805A5072720451 @default.
- W4385547805 hasBestOaLocation W43855478051 @default.
- W4385547805 hasConcept C126322002 @default.
- W4385547805 hasConcept C167135981 @default.
- W4385547805 hasConcept C187212893 @default.
- W4385547805 hasConcept C201903717 @default.
- W4385547805 hasConcept C2777074255 @default.
- W4385547805 hasConcept C2779134260 @default.
- W4385547805 hasConcept C2779761222 @default.
- W4385547805 hasConcept C2993294228 @default.
- W4385547805 hasConcept C526584372 @default.
- W4385547805 hasConcept C71924100 @default.
- W4385547805 hasConcept C72563966 @default.
- W4385547805 hasConceptScore W4385547805C126322002 @default.
- W4385547805 hasConceptScore W4385547805C167135981 @default.
- W4385547805 hasConceptScore W4385547805C187212893 @default.
- W4385547805 hasConceptScore W4385547805C201903717 @default.
- W4385547805 hasConceptScore W4385547805C2777074255 @default.
- W4385547805 hasConceptScore W4385547805C2779134260 @default.
- W4385547805 hasConceptScore W4385547805C2779761222 @default.
- W4385547805 hasConceptScore W4385547805C2993294228 @default.
- W4385547805 hasConceptScore W4385547805C526584372 @default.
- W4385547805 hasConceptScore W4385547805C71924100 @default.
- W4385547805 hasConceptScore W4385547805C72563966 @default.
- W4385547805 hasIssue "Supplement_1" @default.
- W4385547805 hasLocation W43855478051 @default.
- W4385547805 hasOpenAccess W4385547805 @default.
- W4385547805 hasPrimaryLocation W43855478051 @default.
- W4385547805 hasRelatedWork W1490422569 @default.
- W4385547805 hasRelatedWork W1746007799 @default.
- W4385547805 hasRelatedWork W2027626132 @default.
- W4385547805 hasRelatedWork W2034067364 @default.
- W4385547805 hasRelatedWork W2068477286 @default.
- W4385547805 hasRelatedWork W2376710390 @default.
- W4385547805 hasRelatedWork W2410821043 @default.
- W4385547805 hasRelatedWork W2460488226 @default.
- W4385547805 hasRelatedWork W2891651700 @default.
- W4385547805 hasRelatedWork W3032692630 @default.
- W4385547805 hasVolume "9" @default.
- W4385547805 isParatext "false" @default.
- W4385547805 isRetracted "false" @default.
- W4385547805 workType "article" @default.