FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385557158> ?p ?o ?g. }

• W4385557158 endingPage "115564" @default.
• W4385557158 startingPage "115564" @default.
• W4385557158 abstract "The identification and detection of mesenchymal circulating tumor cells （mCTCs） is important for early warning of tumor metastasis. The majority of conventional detection methods for CTCs rely on the recognition of epithelial biomarkers, which is technically challenging for detecting CTCs with epithelial-mesenchymal transition (EMT)-induced phenotypic alteration. In this work, we have constructed a label-free biosensor for sensitive electrochemical assay of mCTCs. In our design, the capture probe can recognize the vimentin overexpressed on the surface of mCTCs with high specificity. Meantime, the network-like DNA nanoprobes with multiple G-quadruplex/hemin complexes and multiple cholesterol molecules can be grafted to the cell surface based on the high affinity between cholesterol molecules and cell membrane. Owing to the mimic horseradish peroxidase of G-quadruplex/hemin complexes, strong electrochemical responses will be obtained for sensitive quantification of mCTCs with a detection limit of 8 cell mL−1. Moreover, the biosensor can effectively overcome the interference of vimentin negative cells or secretory vimentin, and realize the recovery tests in whole blood with high accuracy, thereby may further promoting the diagnosis and personalized treatment of cancer in clinic." @default.
• W4385557158 created "2023-08-04" @default.
• W4385557158 creator A5006411450 @default.
• W4385557158 creator A5009085305 @default.
• W4385557158 creator A5035917075 @default.
• W4385557158 creator A5060507902 @default.
• W4385557158 creator A5072730537 @default.
• W4385557158 creator A5078020955 @default.
• W4385557158 date "2023-10-01" @default.
• W4385557158 modified "2023-09-27" @default.
• W4385557158 title "An electrochemical biosensor based on network-like DNA nanoprobes for detection of mesenchymal circulating tumor cells" @default.
• W4385557158 cites W2071034864 @default.
• W4385557158 cites W2083780033 @default.
• W4385557158 cites W2095554214 @default.
• W4385557158 cites W2272204251 @default.
• W4385557158 cites W2560691444 @default.
• W4385557158 cites W2586407709 @default.
• W4385557158 cites W2733398634 @default.
• W4385557158 cites W2770608080 @default.
• W4385557158 cites W2783337717 @default.
• W4385557158 cites W2791986466 @default.
• W4385557158 cites W2966802060 @default.
• W4385557158 cites W2978292797 @default.
• W4385557158 cites W2980368102 @default.
• W4385557158 cites W2996671700 @default.
• W4385557158 cites W3000198685 @default.
• W4385557158 cites W3005637893 @default.
• W4385557158 cites W3009294427 @default.
• W4385557158 cites W3011490235 @default.
• W4385557158 cites W3018116772 @default.
• W4385557158 cites W3028347143 @default.
• W4385557158 cites W3030461077 @default.
• W4385557158 cites W3038564614 @default.
• W4385557158 cites W3080504986 @default.
• W4385557158 cites W3118473687 @default.
• W4385557158 cites W3158976426 @default.
• W4385557158 cites W3165582094 @default.
• W4385557158 cites W3172416743 @default.
• W4385557158 cites W4210348132 @default.
• W4385557158 cites W4211225392 @default.
• W4385557158 cites W4283272139 @default.
• W4385557158 cites W4293526642 @default.
• W4385557158 doi "https://doi.org/10.1016/j.bios.2023.115564" @default.
• W4385557158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37544105" @default.
• W4385557158 hasPublicationYear "2023" @default.
• W4385557158 type Work @default.
• W4385557158 citedByCount "0" @default.
• W4385557158 crossrefType "journal-article" @default.
• W4385557158 hasAuthorship W4385557158A5006411450 @default.
• W4385557158 hasAuthorship W4385557158A5009085305 @default.
• W4385557158 hasAuthorship W4385557158A5035917075 @default.
• W4385557158 hasAuthorship W4385557158A5060507902 @default.
• W4385557158 hasAuthorship W4385557158A5072730537 @default.
• W4385557158 hasAuthorship W4385557158A5078020955 @default.
• W4385557158 hasConcept C119128265 @default.
• W4385557158 hasConcept C121608353 @default.
• W4385557158 hasConcept C12554922 @default.
• W4385557158 hasConcept C128972844 @default.
• W4385557158 hasConcept C147447768 @default.
• W4385557158 hasConcept C153911025 @default.
• W4385557158 hasConcept C160756335 @default.
• W4385557158 hasConcept C171250308 @default.
• W4385557158 hasConcept C181199279 @default.
• W4385557158 hasConcept C185592680 @default.
• W4385557158 hasConcept C192562407 @default.
• W4385557158 hasConcept C198826908 @default.
• W4385557158 hasConcept C203014093 @default.
• W4385557158 hasConcept C204232928 @default.
• W4385557158 hasConcept C2776217839 @default.
• W4385557158 hasConcept C2777676563 @default.
• W4385557158 hasConcept C2777723881 @default.
• W4385557158 hasConcept C2779013556 @default.
• W4385557158 hasConcept C43617362 @default.
• W4385557158 hasConcept C54355233 @default.
• W4385557158 hasConcept C55493867 @default.
• W4385557158 hasConcept C61238886 @default.
• W4385557158 hasConcept C86803240 @default.
• W4385557158 hasConcept C95444343 @default.
• W4385557158 hasConcept C96232424 @default.
• W4385557158 hasConceptScore W4385557158C119128265 @default.
• W4385557158 hasConceptScore W4385557158C121608353 @default.
• W4385557158 hasConceptScore W4385557158C12554922 @default.
• W4385557158 hasConceptScore W4385557158C128972844 @default.
• W4385557158 hasConceptScore W4385557158C147447768 @default.
• W4385557158 hasConceptScore W4385557158C153911025 @default.
• W4385557158 hasConceptScore W4385557158C160756335 @default.
• W4385557158 hasConceptScore W4385557158C171250308 @default.
• W4385557158 hasConceptScore W4385557158C181199279 @default.
• W4385557158 hasConceptScore W4385557158C185592680 @default.
• W4385557158 hasConceptScore W4385557158C192562407 @default.
• W4385557158 hasConceptScore W4385557158C198826908 @default.
• W4385557158 hasConceptScore W4385557158C203014093 @default.
• W4385557158 hasConceptScore W4385557158C204232928 @default.
• W4385557158 hasConceptScore W4385557158C2776217839 @default.
• W4385557158 hasConceptScore W4385557158C2777676563 @default.
• W4385557158 hasConceptScore W4385557158C2777723881 @default.
• W4385557158 hasConceptScore W4385557158C2779013556 @default.
• W4385557158 hasConceptScore W4385557158C43617362 @default.

• next