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- W4385564785 abstract "Placenta-specific paracrine factors β-estradiol, progesterone, and placental growth factor attenuate flow-mediated constriction of the rate-limiting uterine radial arteries, enabling higher flow rates in pregnancy. These paracrine factors induce their actions in part via nitric oxide mediated mechanisms. A synergistic combination of paracrine factors and shear stress is likely necessary to produce sufficient levels of nitric oxide during early human pregnancy to trigger adequate uterine vascular adaptation." @default.
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- W4385564785 date "2023-10-01" @default.
- W4385564785 modified "2023-09-23" @default.
- W4385564785 title "Synergistic regulation of uterine radial artery adaptation to pregnancy by paracrine and hemodynamic factors" @default.
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- W4385564785 doi "https://doi.org/10.1152/ajpheart.00205.2023" @default.
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