Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385575142> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4385575142 endingPage "35" @default.
- W4385575142 startingPage "25" @default.
- W4385575142 abstract "The inability of epigenetic modifications to control gene expression has been related to a variety of diseases and conditions, including cancer and neurological ailments, amongst others. In recent years, there has been a rise in the amount of attention in pharmacology that is focused on the role that epigenetic modifications play in the response to medicine and the development of drug resistance. This concise review will attempt to provide a synopsis of what is currently known on the influence that epigenetic changes have on the treatment efficacy and resistance mechanisms of various diseases. DNA methylation, histone modifications, and non-coding RNAs are some of the key epigenetic markers that are covered in this article in relation to their function in the pharmacokinetics and pharmacodynamics of drugs. In addition, we highlight the development of approaches that attempt to enhance treatment outcomes while simultaneously overcoming drug resistance by targeting epigenetic alterations. A fundamental understanding of the connection between epigenetics and pharmacological response is required for the development of individualized treatment plans and the identification of novel therapeutic targets." @default.
- W4385575142 created "2023-08-05" @default.
- W4385575142 creator A5008035291 @default.
- W4385575142 creator A5023682426 @default.
- W4385575142 creator A5031695277 @default.
- W4385575142 creator A5045853013 @default.
- W4385575142 creator A5046974847 @default.
- W4385575142 date "2023-07-18" @default.
- W4385575142 modified "2023-09-27" @default.
- W4385575142 title "The Role of Epigenetic Modifications in Drug Response and Resistance" @default.
- W4385575142 doi "https://doi.org/10.46610/jprd.2023.v05i02.003" @default.
- W4385575142 hasPublicationYear "2023" @default.
- W4385575142 type Work @default.
- W4385575142 citedByCount "0" @default.
- W4385575142 crossrefType "journal-article" @default.
- W4385575142 hasAuthorship W4385575142A5008035291 @default.
- W4385575142 hasAuthorship W4385575142A5023682426 @default.
- W4385575142 hasAuthorship W4385575142A5031695277 @default.
- W4385575142 hasAuthorship W4385575142A5045853013 @default.
- W4385575142 hasAuthorship W4385575142A5046974847 @default.
- W4385575142 hasConcept C104317684 @default.
- W4385575142 hasConcept C114851261 @default.
- W4385575142 hasConcept C150194340 @default.
- W4385575142 hasConcept C190727270 @default.
- W4385575142 hasConcept C41091548 @default.
- W4385575142 hasConcept C54355233 @default.
- W4385575142 hasConcept C60644358 @default.
- W4385575142 hasConcept C64927066 @default.
- W4385575142 hasConcept C70721500 @default.
- W4385575142 hasConcept C71924100 @default.
- W4385575142 hasConcept C86803240 @default.
- W4385575142 hasConcept C98274493 @default.
- W4385575142 hasConceptScore W4385575142C104317684 @default.
- W4385575142 hasConceptScore W4385575142C114851261 @default.
- W4385575142 hasConceptScore W4385575142C150194340 @default.
- W4385575142 hasConceptScore W4385575142C190727270 @default.
- W4385575142 hasConceptScore W4385575142C41091548 @default.
- W4385575142 hasConceptScore W4385575142C54355233 @default.
- W4385575142 hasConceptScore W4385575142C60644358 @default.
- W4385575142 hasConceptScore W4385575142C64927066 @default.
- W4385575142 hasConceptScore W4385575142C70721500 @default.
- W4385575142 hasConceptScore W4385575142C71924100 @default.
- W4385575142 hasConceptScore W4385575142C86803240 @default.
- W4385575142 hasConceptScore W4385575142C98274493 @default.
- W4385575142 hasIssue "2" @default.
- W4385575142 hasLocation W43855751421 @default.
- W4385575142 hasOpenAccess W4385575142 @default.
- W4385575142 hasPrimaryLocation W43855751421 @default.
- W4385575142 hasRelatedWork W1982770023 @default.
- W4385575142 hasRelatedWork W2085929781 @default.
- W4385575142 hasRelatedWork W2408523030 @default.
- W4385575142 hasRelatedWork W2500386078 @default.
- W4385575142 hasRelatedWork W2755873664 @default.
- W4385575142 hasRelatedWork W2770520106 @default.
- W4385575142 hasRelatedWork W3032064654 @default.
- W4385575142 hasRelatedWork W3133978408 @default.
- W4385575142 hasRelatedWork W3187936685 @default.
- W4385575142 hasRelatedWork W4310701073 @default.
- W4385575142 hasVolume "5" @default.
- W4385575142 isParatext "false" @default.
- W4385575142 isRetracted "false" @default.
- W4385575142 workType "article" @default.