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- W4385587051 abstract "Radiotherapy plays an important role in definitive and adjuvant cancer therapy; however, some patients experience local recurrence, distant metastasis, or radiation-induced side effects after radiotherapy. Therefore, the identification of molecular targets, radioprotective agents, and mechanisms of radioresistance may improve the outcome of radiation therapy. Preclinical research is helpful to develop targeted therapy for clinical use. A better understanding of the components of the tumor microenvironment can also contribute to improved radiosensitivity. In this overview, we describe the vital intracellular and extracellular roles of immune-related galectin-1 in radiosensitivity and tumor progression. Importantly, radiotherapy can reduce the quality of life and lead to the impairment of dietary intake and subsequent nutrition deprivation. Therefore, we also identify radioprotectors that can reduce radiation-induced small intestine damage. Some useful experimental techniques and methods are introduced to achieve the specific aims proposed." @default.
- W4385587051 created "2023-08-05" @default.
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- W4385587051 date "2023-01-01" @default.
- W4385587051 modified "2023-09-27" @default.
- W4385587051 title "Overview of preclinical research" @default.
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- W4385587051 doi "https://doi.org/10.1016/b978-0-323-88423-5.00049-2" @default.
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