Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385597923> ?p ?o ?g. }
- W4385597923 endingPage "105130" @default.
- W4385597923 startingPage "105130" @default.
- W4385597923 abstract "Long noncoding RNAs (lncRNAs) are increasingly being recognized as modulators in various biological processes. However, due to their low expression, their systematic characterization is difficult to determine. Here, we performed transcript annotation by a newly developed computational pipeline, termed RNA-seq and small RNA-seq combined strategy (RSCS), in a wide variety of cellular contexts. Thousands of high-confidence potential novel transcripts were identified by the RSCS, and the reliability of the transcriptome was verified by analysis of transcript structure, base composition, and sequence complexity. Evidenced by the length comparison, the frequency of the core promoter and the polyadenylation signal motifs, and the locations of transcription start and end sites, the transcripts appear to be full-length. Furthermore, taking advantage of our strategy, we identified a large number of endogenous retrovirus-associated lncRNAs (ERV-lncRNAs), and a novel ERV-lncRNA that was functionally involved in control of Yap1 expression and essential for early embryogenesis was identified. In summary, the RSCS can generate a more complete and precise transcriptome, and our findings greatly expanded the transcriptome annotation for the mammalian community." @default.
- W4385597923 created "2023-08-05" @default.
- W4385597923 creator A5000412277 @default.
- W4385597923 creator A5014610763 @default.
- W4385597923 creator A5022029357 @default.
- W4385597923 creator A5032012513 @default.
- W4385597923 creator A5033796591 @default.
- W4385597923 creator A5056744119 @default.
- W4385597923 creator A5060560991 @default.
- W4385597923 creator A5079258892 @default.
- W4385597923 creator A5083159278 @default.
- W4385597923 creator A5085186808 @default.
- W4385597923 creator A5090592455 @default.
- W4385597923 creator A5092600043 @default.
- W4385597923 date "2023-09-01" @default.
- W4385597923 modified "2023-10-08" @default.
- W4385597923 title "Deep annotation of long noncoding RNAs by assembling RNA-seq and small RNA-seq data" @default.
- W4385597923 cites W1720376523 @default.
- W4385597923 cites W1897931464 @default.
- W4385597923 cites W1965100590 @default.
- W4385597923 cites W1965408671 @default.
- W4385597923 cites W1965854786 @default.
- W4385597923 cites W1969670694 @default.
- W4385597923 cites W1971578941 @default.
- W4385597923 cites W1986504960 @default.
- W4385597923 cites W1998427421 @default.
- W4385597923 cites W1999504956 @default.
- W4385597923 cites W2007439698 @default.
- W4385597923 cites W2011861577 @default.
- W4385597923 cites W2017366798 @default.
- W4385597923 cites W2022199909 @default.
- W4385597923 cites W2023887100 @default.
- W4385597923 cites W2037907723 @default.
- W4385597923 cites W2047285578 @default.
- W4385597923 cites W2048120844 @default.
- W4385597923 cites W2048194168 @default.
- W4385597923 cites W2056419701 @default.
- W4385597923 cites W2060842569 @default.
- W4385597923 cites W2078628283 @default.
- W4385597923 cites W2099468911 @default.
- W4385597923 cites W2102920878 @default.
- W4385597923 cites W2107454957 @default.
- W4385597923 cites W2114703458 @default.
- W4385597923 cites W2121895515 @default.
- W4385597923 cites W2124715997 @default.
- W4385597923 cites W2125577388 @default.
- W4385597923 cites W2129214044 @default.
- W4385597923 cites W2138043022 @default.
- W4385597923 cites W2140921549 @default.
- W4385597923 cites W2145191876 @default.
- W4385597923 cites W2149573463 @default.
- W4385597923 cites W2153268494 @default.
- W4385597923 cites W2155440024 @default.
- W4385597923 cites W2167852161 @default.
- W4385597923 cites W2169674658 @default.
- W4385597923 cites W2177690692 @default.
- W4385597923 cites W2345484738 @default.
- W4385597923 cites W2409262378 @default.
- W4385597923 cites W2413268016 @default.
- W4385597923 cites W2470702181 @default.
- W4385597923 cites W2505384565 @default.
- W4385597923 cites W2510875395 @default.
- W4385597923 cites W2583377988 @default.
- W4385597923 cites W2606095793 @default.
- W4385597923 cites W2615786037 @default.
- W4385597923 cites W2735035409 @default.
- W4385597923 cites W2747899047 @default.
- W4385597923 cites W2760056442 @default.
- W4385597923 cites W2886671568 @default.
- W4385597923 cites W2923862975 @default.
- W4385597923 cites W2963367647 @default.
- W4385597923 cites W2985645328 @default.
- W4385597923 cites W3030724134 @default.
- W4385597923 cites W3085042472 @default.
- W4385597923 cites W4232123484 @default.
- W4385597923 cites W4256010842 @default.
- W4385597923 doi "https://doi.org/10.1016/j.jbc.2023.105130" @default.
- W4385597923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37543366" @default.
- W4385597923 hasPublicationYear "2023" @default.
- W4385597923 type Work @default.
- W4385597923 citedByCount "0" @default.
- W4385597923 crossrefType "journal-article" @default.
- W4385597923 hasAuthorship W4385597923A5000412277 @default.
- W4385597923 hasAuthorship W4385597923A5014610763 @default.
- W4385597923 hasAuthorship W4385597923A5022029357 @default.
- W4385597923 hasAuthorship W4385597923A5032012513 @default.
- W4385597923 hasAuthorship W4385597923A5033796591 @default.
- W4385597923 hasAuthorship W4385597923A5056744119 @default.
- W4385597923 hasAuthorship W4385597923A5060560991 @default.
- W4385597923 hasAuthorship W4385597923A5079258892 @default.
- W4385597923 hasAuthorship W4385597923A5083159278 @default.
- W4385597923 hasAuthorship W4385597923A5085186808 @default.
- W4385597923 hasAuthorship W4385597923A5090592455 @default.
- W4385597923 hasAuthorship W4385597923A5092600043 @default.
- W4385597923 hasBestOaLocation W43855979231 @default.
- W4385597923 hasConcept C104317684 @default.
- W4385597923 hasConcept C107397762 @default.
- W4385597923 hasConcept C142575336 @default.