Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385615796> ?p ?o ?g. }
Showing items 1 to 52 of
52
with 100 items per page.
- W4385615796 abstract "Candida species are considered the most common opportunistic human fungal pathogen due to the presence of various virulence factors, including its ability to form a biofilm that aids in oral candidiasis. Pediatric patients are more susceptible to oral candidiasis than healthy pediatric because of the factors that encourage Candida oral carriage. This current study aims to isolate, evaluated the antifungal effect on Candida spp. and participated in oral candidiasis of pediatric patients in Sulaymaniyah and Kirkuk city. The study was performed from September 2021 to February 2022 on two groups of pediatrics which including pediatric patients (n=160) and healthy pediatric (n=50) as a control group. Oral swabs were obtained from 210 participants in the Kurdistan Region of Iraq at the Pediatric teaching hospital of the Sulaymaneyah and Kirkuk governorates. To culture the swabs, Sabouraud dextrose agar (SDA) medium was used. HiCrome™ Candida Differential agar used to identify Candida isolated, then depending on the internal transcribed spacer (ITS) region using confirmed polymerase chain reaction. Antifungal sensitivity was done for all C. albicans and non-albicans isolates using five common antifungal disks. Among of the 160 sample of pediatric patient 62 (38.8%) positive for Candida spp. which it is including 17 (27.4 %) and 26 (41.9%), 19 (30.6%) breast feeding, bottle feeding and mixing respectively. While within 50 samples of control group 13 (26%) were positive for Candida spp. which including 2 (15.4%), 9(69.2%), 2(15.4%) of same respectively feeding types. Regarding to the antifungal susceptibility the results showed that C. albicans had higher resistance rates against itraconazole, ketoconazole, and clotrimazole than the non-albicans Candida species However, highly resistant rate were detected in Itraconazole and Ketoconazole with 23.7% and 54.4% respectively, for all Candida species. The Current study concluded that oral candidiasis was more predominant in pediatric patients in compare to healthy pediatric also, and C. albicans is the most prevalent etiologic agent. However, higher rate of sensitivity were detected between Candida species for nystatin, which may suggest as the main treatment for oral Candida infections." @default.
- W4385615796 created "2023-08-07" @default.
- W4385615796 date "2023-01-01" @default.
- W4385615796 modified "2023-09-26" @default.
- W4385615796 doi "https://doi.org/10.24017/science/2023.1.5" @default.
- W4385615796 hasPublicationYear "2023" @default.
- W4385615796 type Work @default.
- W4385615796 citedByCount "0" @default.
- W4385615796 crossrefType "journal-issue" @default.
- W4385615796 hasBestOaLocation W43856157961 @default.
- W4385615796 hasConcept C142724271 @default.
- W4385615796 hasConcept C145081991 @default.
- W4385615796 hasConcept C2776460866 @default.
- W4385615796 hasConcept C2778660310 @default.
- W4385615796 hasConcept C2779548794 @default.
- W4385615796 hasConcept C2780917455 @default.
- W4385615796 hasConcept C32762888 @default.
- W4385615796 hasConcept C523546767 @default.
- W4385615796 hasConcept C54355233 @default.
- W4385615796 hasConcept C71924100 @default.
- W4385615796 hasConcept C86803240 @default.
- W4385615796 hasConcept C89423630 @default.
- W4385615796 hasConceptScore W4385615796C142724271 @default.
- W4385615796 hasConceptScore W4385615796C145081991 @default.
- W4385615796 hasConceptScore W4385615796C2776460866 @default.
- W4385615796 hasConceptScore W4385615796C2778660310 @default.
- W4385615796 hasConceptScore W4385615796C2779548794 @default.
- W4385615796 hasConceptScore W4385615796C2780917455 @default.
- W4385615796 hasConceptScore W4385615796C32762888 @default.
- W4385615796 hasConceptScore W4385615796C523546767 @default.
- W4385615796 hasConceptScore W4385615796C54355233 @default.
- W4385615796 hasConceptScore W4385615796C71924100 @default.
- W4385615796 hasConceptScore W4385615796C86803240 @default.
- W4385615796 hasConceptScore W4385615796C89423630 @default.
- W4385615796 hasIssue "1" @default.
- W4385615796 hasLocation W43856157961 @default.
- W4385615796 hasOpenAccess W4385615796 @default.
- W4385615796 hasPrimaryLocation W43856157961 @default.
- W4385615796 hasRelatedWork W1801898498 @default.
- W4385615796 hasRelatedWork W1959028738 @default.
- W4385615796 hasRelatedWork W2620600560 @default.
- W4385615796 hasRelatedWork W2945082719 @default.
- W4385615796 hasRelatedWork W2946449973 @default.
- W4385615796 hasRelatedWork W3107998850 @default.
- W4385615796 hasRelatedWork W4285012569 @default.
- W4385615796 hasRelatedWork W4297252087 @default.
- W4385615796 hasRelatedWork W4300690271 @default.
- W4385615796 hasRelatedWork W7163209 @default.
- W4385615796 hasVolume "8" @default.
- W4385615796 isParatext "false" @default.
- W4385615796 isRetracted "false" @default.
- W4385615796 workType "paratext" @default.