FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385638411> ?p ?o ?g. }

• W4385638411 endingPage "126171" @default.
• W4385638411 startingPage "126171" @default.
• W4385638411 abstract "Naturally occurring biopolymers like exopolysaccharides (EPS) secreted by lactic acid bacteria (LAB) has gained significant attention as they are cost effective, renewable and safe. In order to prevent the rapid increase in antibiotic resistant bacteria, the EPS of LAB offers novel approach of targeting the antibiotic resistant pathogens by limiting their effects on environment. Accordingly, in this study, the production, purification, characterization and biological properties of exopolysaccharides from Lactococcus hircilactis strain CH4 and Lactobacillus delbrueckii strain GRIPUMSK were performed. The optimization of lactic acid bacterial strains for exopolysaccharide production was done by response surface methodology and changing the carbon sources in the growth media. The carbohydrate and protein of exopolysaccharide 1 were 79.7 % and 8.7 % respectively and exopolysaccharide 2 were 75.2 % and 9.3 % respectively. When compared with the commercial emulsifier sodium dodecyl sulfate, both the exopolysaccharides have shown good emulsifying activity. Both the exopolysaccharides were linear homo-polysaccharide as determined by Fourier transform infrared spectroscopy and Nuclear magnetic resonance spectra. Scanning electron microscopy showed that the exopolysaccharides were porous and capable of holding water. The exopolysaccharides were partially crystalline as confirmed by X-ray diffraction spectra. Exopolysaccharides from L. hircilactis and L. delbrueckii exhibited significant antimicrobial activity against H. pylori, S. flexneri, S. pyogenes, E. faecalis and C. albicans. Both the exopolysaccharides revealed significant 2,2-diphenyl-1-picrylhydrazyl and hydrogen peroxide scavenging ability with the IC50 value of 100 μg/ml and 80 μg/ml respectively. Exopolysaccharides from L. hircilactis and L. delbrueckii at 100 μg/ml showed significant anticancer activity on HT-29 cells with 58.4 % and 58.7 % respectively. These findings proved that exopolysaccharides from the two selected lactic acid bacterial strains could be explored as natural bioactive carbohydrate polymer for biomedical applications." @default.
• W4385638411 created "2023-08-08" @default.
• W4385638411 creator A5024286088 @default.
• W4385638411 creator A5063167540 @default.
• W4385638411 creator A5082765484 @default.
• W4385638411 creator A5092607965 @default.
• W4385638411 date "2023-10-01" @default.
• W4385638411 modified "2023-10-18" @default.
• W4385638411 title "Exopolysaccharide from Lactococcus hircilactis CH4 and Lactobacillus delbrueckii GRIPUMSK as new therapeutics to treat biofilm pathogens, oxidative stress and human colon adenocarcinoma" @default.
• W4385638411 cites W2001015437 @default.
• W4385638411 cites W2001121649 @default.
• W4385638411 cites W2007453173 @default.
• W4385638411 cites W2043878586 @default.
• W4385638411 cites W2078751179 @default.
• W4385638411 cites W2089054156 @default.
• W4385638411 cites W2194583909 @default.
• W4385638411 cites W2396979016 @default.
• W4385638411 cites W2516466510 @default.
• W4385638411 cites W2519875205 @default.
• W4385638411 cites W2543259773 @default.
• W4385638411 cites W2567155626 @default.
• W4385638411 cites W2592675245 @default.
• W4385638411 cites W2738119216 @default.
• W4385638411 cites W2766149345 @default.
• W4385638411 cites W2767437369 @default.
• W4385638411 cites W2769991380 @default.
• W4385638411 cites W2809310587 @default.
• W4385638411 cites W2890982821 @default.
• W4385638411 cites W2903260597 @default.
• W4385638411 cites W2919935219 @default.
• W4385638411 cites W2937181625 @default.
• W4385638411 cites W2942591360 @default.
• W4385638411 cites W2967161386 @default.
• W4385638411 cites W2967923907 @default.
• W4385638411 cites W2967990172 @default.
• W4385638411 cites W2969570006 @default.
• W4385638411 cites W2975332233 @default.
• W4385638411 cites W2984244695 @default.
• W4385638411 cites W2996382792 @default.
• W4385638411 cites W2997907728 @default.
• W4385638411 cites W3014612508 @default.
• W4385638411 cites W3017330008 @default.
• W4385638411 cites W3035535272 @default.
• W4385638411 cites W3043186230 @default.
• W4385638411 cites W3124374706 @default.
• W4385638411 cites W3125788508 @default.
• W4385638411 cites W3136046322 @default.
• W4385638411 cites W3162369158 @default.
• W4385638411 cites W3173698693 @default.
• W4385638411 cites W3174863033 @default.
• W4385638411 cites W3185076170 @default.
• W4385638411 cites W3193261079 @default.
• W4385638411 cites W3195117358 @default.
• W4385638411 cites W3206135411 @default.
• W4385638411 cites W3210365933 @default.
• W4385638411 cites W4200127036 @default.
• W4385638411 cites W4220693478 @default.
• W4385638411 cites W4220732926 @default.
• W4385638411 cites W4280493760 @default.
• W4385638411 cites W4282835366 @default.
• W4385638411 cites W4282970737 @default.
• W4385638411 cites W4283366444 @default.
• W4385638411 cites W4289929046 @default.
• W4385638411 cites W4292487846 @default.
• W4385638411 cites W4313814655 @default.
• W4385638411 cites W4362589570 @default.
• W4385638411 cites W4378639322 @default.
• W4385638411 doi "https://doi.org/10.1016/j.ijbiomac.2023.126171" @default.
• W4385638411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37558015" @default.
• W4385638411 hasPublicationYear "2023" @default.
• W4385638411 type Work @default.
• W4385638411 citedByCount "0" @default.
• W4385638411 crossrefType "journal-article" @default.
• W4385638411 hasAuthorship W4385638411A5024286088 @default.
• W4385638411 hasAuthorship W4385638411A5063167540 @default.
• W4385638411 hasAuthorship W4385638411A5082765484 @default.
• W4385638411 hasAuthorship W4385638411A5092607965 @default.
• W4385638411 hasConcept C100544194 @default.
• W4385638411 hasConcept C100817775 @default.
• W4385638411 hasConcept C185592680 @default.
• W4385638411 hasConcept C2775920511 @default.
• W4385638411 hasConcept C2780206646 @default.
• W4385638411 hasConcept C31903555 @default.
• W4385638411 hasConcept C523546767 @default.
• W4385638411 hasConcept C54355233 @default.
• W4385638411 hasConcept C55493867 @default.
• W4385638411 hasConcept C58123911 @default.
• W4385638411 hasConcept C86803240 @default.
• W4385638411 hasConcept C89423630 @default.
• W4385638411 hasConceptScore W4385638411C100544194 @default.
• W4385638411 hasConceptScore W4385638411C100817775 @default.
• W4385638411 hasConceptScore W4385638411C185592680 @default.
• W4385638411 hasConceptScore W4385638411C2775920511 @default.
• W4385638411 hasConceptScore W4385638411C2780206646 @default.
• W4385638411 hasConceptScore W4385638411C31903555 @default.
• W4385638411 hasConceptScore W4385638411C523546767 @default.
• W4385638411 hasConceptScore W4385638411C54355233 @default.
• W4385638411 hasConceptScore W4385638411C55493867 @default.

• next