Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385655260> ?p ?o ?g. }
- W4385655260 endingPage "3499" @default.
- W4385655260 startingPage "3499" @default.
- W4385655260 abstract "Due to the rising demand for supplements targeting cognitive enhancement and dry eye together with the health benefits of anthocyanins, we have developed a functional soup containing an anthocyanin-rich functional ingredient, or Anthaplex, and assessed the effects on cognitive function and eye dryness together with the possible mechanisms. A total of 69 male and female health volunteers were randomized and divided into placebo, D2, and D4 groups. All subjects consumed 120 mL of placebo or functional soup containing Anthaplex either at 2 or 4 g per serving per day within 5 min in the morning for eight weeks. The cognitive function, working memory, dry eye, AChE, MAO, MAO-A, MAO-B, and GABA-T activities, BDNF, HAC, HDAC, and DNMT activities, pH, and amount of lactic acid-producing bacteria, particularly Lactobacillus and Bifidobacterium spp. in feces, were determined before intervention and after eight weeks of consumption. Subjects who consumed the Anthaplex soup had improved cognitive function, working memory, eye dryness, histone acetylation, ACh E suppression, and BDNF with increased Bifidobacterium spp. but decreased pH in feces. These data suggest that Anthaplex improves cognitive function and eye dryness via the modulations of the histone acetylation process, gut microbiome, and cholinergic function." @default.
- W4385655260 created "2023-08-09" @default.
- W4385655260 creator A5016404456 @default.
- W4385655260 creator A5032585406 @default.
- W4385655260 creator A5050243131 @default.
- W4385655260 creator A5073653580 @default.
- W4385655260 creator A5089020889 @default.
- W4385655260 date "2023-08-08" @default.
- W4385655260 modified "2023-09-26" @default.
- W4385655260 title "A Randomized, Double-Blind, Placebo-Controlled Study of an Anthocyanin-Rich Functional Ingredient on Cognitive Function and Eye Dryness in Late Adulthood Volunteers: Roles of Epigenetic and Gut Microbiome Modulations" @default.
- W4385655260 cites W1513824076 @default.
- W4385655260 cites W1659162627 @default.
- W4385655260 cites W1811948089 @default.
- W4385655260 cites W1850203528 @default.
- W4385655260 cites W1969061520 @default.
- W4385655260 cites W1984677501 @default.
- W4385655260 cites W2036681126 @default.
- W4385655260 cites W2048592243 @default.
- W4385655260 cites W2050450731 @default.
- W4385655260 cites W2054450240 @default.
- W4385655260 cites W2065710786 @default.
- W4385655260 cites W2085907924 @default.
- W4385655260 cites W2090552566 @default.
- W4385655260 cites W2114240300 @default.
- W4385655260 cites W2114607335 @default.
- W4385655260 cites W2122602360 @default.
- W4385655260 cites W2130256699 @default.
- W4385655260 cites W2137116499 @default.
- W4385655260 cites W2146214392 @default.
- W4385655260 cites W2146594405 @default.
- W4385655260 cites W2150624246 @default.
- W4385655260 cites W2152039382 @default.
- W4385655260 cites W2161038635 @default.
- W4385655260 cites W2171039595 @default.
- W4385655260 cites W2175015138 @default.
- W4385655260 cites W2489380376 @default.
- W4385655260 cites W2596391620 @default.
- W4385655260 cites W2611728656 @default.
- W4385655260 cites W2613603704 @default.
- W4385655260 cites W2731601089 @default.
- W4385655260 cites W2749128772 @default.
- W4385655260 cites W2762114887 @default.
- W4385655260 cites W2780398151 @default.
- W4385655260 cites W2796548508 @default.
- W4385655260 cites W2806614313 @default.
- W4385655260 cites W2884802815 @default.
- W4385655260 cites W2918871723 @default.
- W4385655260 cites W2921226990 @default.
- W4385655260 cites W2943210908 @default.
- W4385655260 cites W2954044249 @default.
- W4385655260 cites W2963936193 @default.
- W4385655260 cites W2972458950 @default.
- W4385655260 cites W2978282877 @default.
- W4385655260 cites W2982987663 @default.
- W4385655260 cites W3017160392 @default.
- W4385655260 cites W3037076591 @default.
- W4385655260 cites W3038541118 @default.
- W4385655260 cites W3086467607 @default.
- W4385655260 cites W3092961660 @default.
- W4385655260 cites W3100905348 @default.
- W4385655260 cites W3122961198 @default.
- W4385655260 cites W3125634225 @default.
- W4385655260 cites W3128032880 @default.
- W4385655260 cites W3133846109 @default.
- W4385655260 cites W3134433092 @default.
- W4385655260 cites W3164357913 @default.
- W4385655260 cites W3188997258 @default.
- W4385655260 cites W3196567357 @default.
- W4385655260 cites W3196738190 @default.
- W4385655260 cites W3214589207 @default.
- W4385655260 cites W3216353248 @default.
- W4385655260 cites W4220999839 @default.
- W4385655260 cites W4225263021 @default.
- W4385655260 cites W4225843187 @default.
- W4385655260 cites W4283728127 @default.
- W4385655260 cites W4291926368 @default.
- W4385655260 cites W4294808299 @default.
- W4385655260 cites W4297540022 @default.
- W4385655260 cites W4308580984 @default.
- W4385655260 doi "https://doi.org/10.3390/nu15163499" @default.
- W4385655260 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37630690" @default.
- W4385655260 hasPublicationYear "2023" @default.
- W4385655260 type Work @default.
- W4385655260 citedByCount "0" @default.
- W4385655260 crossrefType "journal-article" @default.
- W4385655260 hasAuthorship W4385655260A5016404456 @default.
- W4385655260 hasAuthorship W4385655260A5032585406 @default.
- W4385655260 hasAuthorship W4385655260A5050243131 @default.
- W4385655260 hasAuthorship W4385655260A5073653580 @default.
- W4385655260 hasAuthorship W4385655260A5089020889 @default.
- W4385655260 hasBestOaLocation W43856552601 @default.
- W4385655260 hasConcept C100544194 @default.
- W4385655260 hasConcept C142724271 @default.
- W4385655260 hasConcept C204787440 @default.
- W4385655260 hasConcept C27081682 @default.
- W4385655260 hasConcept C2778945092 @default.
- W4385655260 hasConcept C2780206646 @default.
- W4385655260 hasConcept C2780255968 @default.