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- W4385660108 abstract "Rosai-Dorfman disease (RDD) is a rare, S100-positive histiocytic proliferation, that can cause both nodal and extranodal illness. We present a case of a 53-year-old male patient. Magnetic resonance imaging described a plaque-like meningeal lesion, and the preoperative diagnosis was meningioma. Histologically, dense infiltration of lymphocytes, plasma cells, and histiocytes was seen, furthermore, the presence of emperipolesis in the sample was pronounced. In the histiocytes nuclear and cytoplasmic positivity with S100 protein, and nuclear positivity with Cyclin D1 was observed. The case was concluded as RDD. Morphological appearance of intracranial RDD with imaging procedures can present a differential diagnostic challenge. The correct diagnosis is based on the presence of histiocytes with emperipolesis, and properly defined immunohistochemical characteristics." @default.
- W4385660108 created "2023-08-09" @default.
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- W4385660108 date "2023-08-08" @default.
- W4385660108 modified "2023-10-16" @default.
- W4385660108 title "Cerebral manifestation and diagnostic dilemma of Rosai-Dorfman disease" @default.
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- W4385660108 doi "https://doi.org/10.2217/cns-2023-0006" @default.
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