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- W4385684137 abstract "Objectives Prediction of the risk of esophageal squamous cell carcinoma (SCC) by endoscopic findings without iodine staining, which is irritating to the esophagus, would be beneficial. In a previous retrospective study, we found that multiple foci of dilated vascular areas (MDV) of the esophageal mucosa, seen in narrow‐band imaging (NBI)/blue laser imaging (BLI), are associated with iodine‐unstained lesions and, thus, may be a predictor of esophageal SCC. This prospective study aimed to investigate the association between MDV and metachronous esophageal SCC. Methods Patients with a history of endoscopic resection for esophageal SCC were included in the study. First, evaluation of the MDV using NBI or BLI was conducted during the initial endoscopy. The patients were then monitored for metachronous esophageal SCC by endoscopic surveillance. The association between the number of MDV and incidence of metachronous esophageal SCC was investigated. Results From February 2018 to May 2019, 206 patients were enrolled and 201 patients were included in the analysis. Patients were followed up until October 2022. The median (interquartile range) endoscopic follow‐up period was 1260 (1105–1348) days. The incidence of metachronous esophageal SCC at 2 years was 7.1% in patients with MDV ≤4 and 13.9% in patients with MDV ≥5 ( P < 0.01). In the multivariate analysis, MDV was an independent predictor of metachronous esophageal SCC, with an odds ratio (95% confidence interval) of 2.37 (1.06–5.31). Conclusion Multiple foci of dilated vascular area is a useful predictor for stratifying the risk of metachronous esophageal SCC." @default.
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- W4385684137 date "2023-08-29" @default.
- W4385684137 modified "2023-09-26" @default.
- W4385684137 title "Multiple foci of dilated vessels as a new predictor of metachronous esophageal cancer" @default.
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- W4385684137 doi "https://doi.org/10.1111/den.14657" @default.
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