FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385684208> ?p ?o ?g. }

• W4385684208 endingPage "10" @default.
• W4385684208 startingPage "1" @default.
• W4385684208 abstract "There are phenomenological similarities between social anxiety disorder (SAD) and posttraumatic stress disorder, such as a provoking aversive event, posttraumatic stress symptoms (e.g. intrusions) in response to these events and deficient (context-dependent) fear conditioning processes. This study investigated the neural correlates of context-dependent extinction recall and fear renewal in SAD, specifically in patients with intrusions in response to an etiologically relevant aversive social event.During functional magnetic resonance imaging a two-day context-dependent fear conditioning paradigm was conducted in 54 patients with SAD and 54 healthy controls (HC). This included fear acquisition (context A) and extinction learning (context B) on one day, and extinction recall (context B) as well as fear renewal (contexts C and A) one day later. The main outcome measures were blood oxygen level-dependent responses in regions of interest and skin conductance responses.Patients with SAD showed reduced differential conditioned amygdala activation during extinction recall in the safe extinction context and during fear renewal in the acquisition context compared to HC. Patients with clinically relevant intrusions moreover exhibited hypoactivation of the ventromedial prefrontal cortex (vmPFC) during extinction learning, extinction recall, and fear renewal in a novel context, while amygdala activation more strongly decreased during extinction learning and increased during fear renewal in the acquisition context compared with patients without intrusions.Our study provides first evidence that intrusions in SAD are associated with similar deficits in context-dependent regulation of conditioned fear via the vmPFC as previously demonstrated in posttraumatic stress disorder." @default.
• W4385684208 created "2023-08-10" @default.
• W4385684208 creator A5007479303 @default.
• W4385684208 creator A5013713234 @default.
• W4385684208 creator A5021437905 @default.
• W4385684208 creator A5044378046 @default.
• W4385684208 creator A5045026567 @default.
• W4385684208 creator A5066522017 @default.
• W4385684208 creator A5076035198 @default.
• W4385684208 date "2023-08-09" @default.
• W4385684208 modified "2023-10-14" @default.
• W4385684208 title "Neural correlates of context-dependent extinction recall in social anxiety disorder: relevance of intrusions in response to aversive social experiences" @default.
• W4385684208 cites W1509990832 @default.
• W4385684208 cites W1519591349 @default.
• W4385684208 cites W1555297499 @default.
• W4385684208 cites W1597129241 @default.
• W4385684208 cites W1902137069 @default.
• W4385684208 cites W1969348782 @default.
• W4385684208 cites W1969441531 @default.
• W4385684208 cites W1972090415 @default.
• W4385684208 cites W1978489779 @default.
• W4385684208 cites W1983067890 @default.
• W4385684208 cites W1992253412 @default.
• W4385684208 cites W1992748384 @default.
• W4385684208 cites W1992814944 @default.
• W4385684208 cites W2000465322 @default.
• W4385684208 cites W2001756449 @default.
• W4385684208 cites W2002459043 @default.
• W4385684208 cites W2003907085 @default.
• W4385684208 cites W2005190428 @default.
• W4385684208 cites W2008691066 @default.
• W4385684208 cites W2031503422 @default.
• W4385684208 cites W2036537456 @default.
• W4385684208 cites W2039810696 @default.
• W4385684208 cites W2049812132 @default.
• W4385684208 cites W2064135174 @default.
• W4385684208 cites W2066642195 @default.
• W4385684208 cites W2077083873 @default.
• W4385684208 cites W2087484885 @default.
• W4385684208 cites W2095958248 @default.
• W4385684208 cites W2096623209 @default.
• W4385684208 cites W2103791867 @default.
• W4385684208 cites W2111544318 @default.
• W4385684208 cites W2113485684 @default.
• W4385684208 cites W2125030784 @default.
• W4385684208 cites W2138983202 @default.
• W4385684208 cites W2140201388 @default.
• W4385684208 cites W2146873048 @default.
• W4385684208 cites W2155107316 @default.
• W4385684208 cites W2165108457 @default.
• W4385684208 cites W2301610793 @default.
• W4385684208 cites W2333576952 @default.
• W4385684208 cites W2408821135 @default.
• W4385684208 cites W2417444216 @default.
• W4385684208 cites W2522302102 @default.
• W4385684208 cites W2524355626 @default.
• W4385684208 cites W2528659983 @default.
• W4385684208 cites W2532103088 @default.
• W4385684208 cites W2592888702 @default.
• W4385684208 cites W2607453530 @default.
• W4385684208 cites W2746196658 @default.
• W4385684208 cites W2769879830 @default.
• W4385684208 cites W2792207924 @default.
• W4385684208 cites W2952159692 @default.
• W4385684208 cites W2954703655 @default.
• W4385684208 cites W2969442953 @default.
• W4385684208 cites W2997502313 @default.
• W4385684208 cites W3004708860 @default.
• W4385684208 cites W3017146922 @default.
• W4385684208 cites W3018088717 @default.
• W4385684208 cites W3035802378 @default.
• W4385684208 cites W3090145360 @default.
• W4385684208 cites W3090630974 @default.
• W4385684208 cites W3134342761 @default.
• W4385684208 cites W3146571660 @default.
• W4385684208 cites W4241727644 @default.
• W4385684208 cites W78630970 @default.
• W4385684208 doi "https://doi.org/10.1017/s0033291723002179" @default.
• W4385684208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37553977" @default.
• W4385684208 hasPublicationYear "2023" @default.
• W4385684208 type Work @default.
• W4385684208 citedByCount "0" @default.
• W4385684208 crossrefType "journal-article" @default.
• W4385684208 hasAuthorship W4385684208A5007479303 @default.
• W4385684208 hasAuthorship W4385684208A5013713234 @default.
• W4385684208 hasAuthorship W4385684208A5021437905 @default.
• W4385684208 hasAuthorship W4385684208A5044378046 @default.
• W4385684208 hasAuthorship W4385684208A5045026567 @default.
• W4385684208 hasAuthorship W4385684208A5066522017 @default.
• W4385684208 hasAuthorship W4385684208A5076035198 @default.
• W4385684208 hasBestOaLocation W43856842081 @default.
• W4385684208 hasConcept C100660578 @default.
• W4385684208 hasConcept C100798922 @default.
• W4385684208 hasConcept C101991246 @default.
• W4385684208 hasConcept C118552586 @default.
• W4385684208 hasConcept C129564537 @default.
• W4385684208 hasConcept C151730666 @default.
• W4385684208 hasConcept C15744967 @default.

• next