Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385684257> ?p ?o ?g. }
- W4385684257 abstract "Abstract Background Normothermic machine perfusion (NMP) provides a novel platform to preserve isolated organs in an artificial condition. Our study aimed to explore the interaction between the liver and kidney at an ex vivo organ level by adding a liver to the kidney NMP circuit. Methods Porcine kidney and liver obtained from abattoir were subjected to 9 h NMP after suffering 30‐min warm ischemia time and 90‐min cold ischemia time. The liver–kidney NMP group ( n = 5) and the single‐kidney NMP group ( n = 5) were designed. During the NMP, perfusion parameters, blood gas analysis, and tissue samples were compared. Results The perfusate of both groups remained stable, and continuous urine production was observed during NMP. In the liver–kidney NMP group, the lactate level was low, while blood urea nitrogen increased and glucose levels decreased. After the NMP, the renal tissue in the liver–kidney group exhibited fewer histological changes such as tubular epithelium vacuolization, along with reduced expression of IL‐6, IL‐8, IL‐1β, NLRP3, and GSDMD. Conclusions Our results indicated that the expression of renal pro‐inflammatory factors was reduced in the liver–kidney NMP system." @default.
- W4385684257 created "2023-08-10" @default.
- W4385684257 creator A5000156878 @default.
- W4385684257 creator A5018196994 @default.
- W4385684257 creator A5033412962 @default.
- W4385684257 creator A5046507515 @default.
- W4385684257 creator A5060711111 @default.
- W4385684257 creator A5061481279 @default.
- W4385684257 creator A5072845150 @default.
- W4385684257 creator A5073346815 @default.
- W4385684257 creator A5080958120 @default.
- W4385684257 creator A5083393257 @default.
- W4385684257 creator A5085654642 @default.
- W4385684257 date "2023-08-08" @default.
- W4385684257 modified "2023-09-26" @default.
- W4385684257 title "Addition of a liver to the normothermic perfusion circuit reduces renal pro‐inflammatory factors" @default.
- W4385684257 cites W1766088852 @default.
- W4385684257 cites W1894478541 @default.
- W4385684257 cites W1985970823 @default.
- W4385684257 cites W2020347637 @default.
- W4385684257 cites W2030965929 @default.
- W4385684257 cites W2078319735 @default.
- W4385684257 cites W2254417733 @default.
- W4385684257 cites W2315690141 @default.
- W4385684257 cites W2321715992 @default.
- W4385684257 cites W2339867747 @default.
- W4385684257 cites W2414027750 @default.
- W4385684257 cites W2462773201 @default.
- W4385684257 cites W2509878167 @default.
- W4385684257 cites W2523430665 @default.
- W4385684257 cites W2573544994 @default.
- W4385684257 cites W2579961309 @default.
- W4385684257 cites W2599822883 @default.
- W4385684257 cites W2761684155 @default.
- W4385684257 cites W2798029993 @default.
- W4385684257 cites W2803685415 @default.
- W4385684257 cites W2808858647 @default.
- W4385684257 cites W2886866003 @default.
- W4385684257 cites W2946841468 @default.
- W4385684257 cites W3006834721 @default.
- W4385684257 cites W3024991608 @default.
- W4385684257 cites W3028015231 @default.
- W4385684257 cites W3084291317 @default.
- W4385684257 cites W3087255930 @default.
- W4385684257 cites W3094559662 @default.
- W4385684257 cites W3123152700 @default.
- W4385684257 cites W3128723827 @default.
- W4385684257 cites W3149432772 @default.
- W4385684257 cites W3161177524 @default.
- W4385684257 cites W4200621431 @default.
- W4385684257 cites W4247878364 @default.
- W4385684257 cites W4285392353 @default.
- W4385684257 doi "https://doi.org/10.1111/aor.14626" @default.
- W4385684257 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37553847" @default.
- W4385684257 hasPublicationYear "2023" @default.
- W4385684257 type Work @default.
- W4385684257 citedByCount "0" @default.
- W4385684257 crossrefType "journal-article" @default.
- W4385684257 hasAuthorship W4385684257A5000156878 @default.
- W4385684257 hasAuthorship W4385684257A5018196994 @default.
- W4385684257 hasAuthorship W4385684257A5033412962 @default.
- W4385684257 hasAuthorship W4385684257A5046507515 @default.
- W4385684257 hasAuthorship W4385684257A5060711111 @default.
- W4385684257 hasAuthorship W4385684257A5061481279 @default.
- W4385684257 hasAuthorship W4385684257A5072845150 @default.
- W4385684257 hasAuthorship W4385684257A5073346815 @default.
- W4385684257 hasAuthorship W4385684257A5080958120 @default.
- W4385684257 hasAuthorship W4385684257A5083393257 @default.
- W4385684257 hasAuthorship W4385684257A5085654642 @default.
- W4385684257 hasConcept C126322002 @default.
- W4385684257 hasConcept C126894567 @default.
- W4385684257 hasConcept C134018914 @default.
- W4385684257 hasConcept C142724271 @default.
- W4385684257 hasConcept C146957229 @default.
- W4385684257 hasConcept C150903083 @default.
- W4385684257 hasConcept C16685009 @default.
- W4385684257 hasConcept C185592680 @default.
- W4385684257 hasConcept C207001950 @default.
- W4385684257 hasConcept C26291073 @default.
- W4385684257 hasConcept C2778176769 @default.
- W4385684257 hasConcept C2778614373 @default.
- W4385684257 hasConcept C2779288732 @default.
- W4385684257 hasConcept C2779609443 @default.
- W4385684257 hasConcept C2780091579 @default.
- W4385684257 hasConcept C2911091166 @default.
- W4385684257 hasConcept C541997718 @default.
- W4385684257 hasConcept C71924100 @default.
- W4385684257 hasConcept C86803240 @default.
- W4385684257 hasConceptScore W4385684257C126322002 @default.
- W4385684257 hasConceptScore W4385684257C126894567 @default.
- W4385684257 hasConceptScore W4385684257C134018914 @default.
- W4385684257 hasConceptScore W4385684257C142724271 @default.
- W4385684257 hasConceptScore W4385684257C146957229 @default.
- W4385684257 hasConceptScore W4385684257C150903083 @default.
- W4385684257 hasConceptScore W4385684257C16685009 @default.
- W4385684257 hasConceptScore W4385684257C185592680 @default.
- W4385684257 hasConceptScore W4385684257C207001950 @default.
- W4385684257 hasConceptScore W4385684257C26291073 @default.
- W4385684257 hasConceptScore W4385684257C2778176769 @default.
- W4385684257 hasConceptScore W4385684257C2778614373 @default.