FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385684857> ?p ?o ?g. }

• W4385684857 endingPage "404" @default.
• W4385684857 startingPage "393" @default.
• W4385684857 abstract "The prognostic markers of lung squamous cell carcinoma (LSCC) are less investigated. The aim of our study was to evaluate tumour budding (TB), minimal cell nest size, nuclear diameter (ND), and spread through air spaces (STAS) among patients with resected LSCC, semi-quantitatively. Furthermore, we aimed to identify a grading system for the best prognostic stratification of LSCC. Patients who underwent surgical resection at the Department of Surgery, University of Szeged between 2010 and 2016 were included. Follow-up data were collected from medical charts. Morphological characteristics were recorded from histologic revision of slides. Kaplan-Meier analysis, log rank test and Cox proportional-hazards model, ROC curve analysis, and intraclass correlation were utilised. Altogether 220 patients were included. In univariate analysis, higher degree of TB, infiltrative tumour border, larger ND, the presence of single cell invasion (SCI) and STAS were associated with adverse prognosis. Based on our results, we proposed an easily applicable grading scheme focusing on TB, ND, and SCI. In multivariate analysis, the proposed grading system (pOS < 0.001, pRFS < 0.001) and STAS (pOS = 0.008, pRFS < 0.001) were independent prognosticators. Compared to the previously introduced grading systems, ROC curve analysis revealed that the proposed grade had the highest AUC values (AUCOS: 0.83, AUCRFS: 0.78). Each category of the proposed grading system has good (ICC: 0.79-0.88) reproducibility. We validated the prognostic impact of TB, SCI, ND, and STAS in LSCC. We recommend a reproducible grading system combining TB, SCI, and ND for proper prognostic stratification of LSCC patients. Further research is required for validation of this grading scheme." @default.
• W4385684857 created "2023-08-10" @default.
• W4385684857 creator A5023565241 @default.
• W4385684857 creator A5034025853 @default.
• W4385684857 creator A5043962045 @default.
• W4385684857 creator A5053322701 @default.
• W4385684857 creator A5053906317 @default.
• W4385684857 creator A5056308350 @default.
• W4385684857 creator A5057257315 @default.
• W4385684857 creator A5068440444 @default.
• W4385684857 date "2023-08-09" @default.
• W4385684857 modified "2023-10-05" @default.
• W4385684857 title "Proposal of a grading system for squamous cell carcinoma of the lung — the prognostic importance of tumour budding, single cell invasion, and nuclear diameter" @default.
• W4385684857 cites W1953677527 @default.
• W4385684857 cites W1970912753 @default.
• W4385684857 cites W1975417270 @default.
• W4385684857 cites W1981989535 @default.
• W4385684857 cites W1983532504 @default.
• W4385684857 cites W1994838678 @default.
• W4385684857 cites W1997554723 @default.
• W4385684857 cites W1998576236 @default.
• W4385684857 cites W1998668334 @default.
• W4385684857 cites W1999170760 @default.
• W4385684857 cites W1999490101 @default.
• W4385684857 cites W2006213157 @default.
• W4385684857 cites W2006611100 @default.
• W4385684857 cites W2013842287 @default.
• W4385684857 cites W2015537995 @default.
• W4385684857 cites W2043458700 @default.
• W4385684857 cites W2055551546 @default.
• W4385684857 cites W2057067430 @default.
• W4385684857 cites W2073708753 @default.
• W4385684857 cites W2084343028 @default.
• W4385684857 cites W2088720324 @default.
• W4385684857 cites W2094290949 @default.
• W4385684857 cites W2144183889 @default.
• W4385684857 cites W2161324764 @default.
• W4385684857 cites W2162635767 @default.
• W4385684857 cites W2251438188 @default.
• W4385684857 cites W2313702627 @default.
• W4385684857 cites W2327037637 @default.
• W4385684857 cites W2502134830 @default.
• W4385684857 cites W2518445393 @default.
• W4385684857 cites W2526112332 @default.
• W4385684857 cites W2550753355 @default.
• W4385684857 cites W2593390134 @default.
• W4385684857 cites W2620163964 @default.
• W4385684857 cites W2736757837 @default.
• W4385684857 cites W2773892231 @default.
• W4385684857 cites W2785355654 @default.
• W4385684857 cites W2909380380 @default.
• W4385684857 cites W2945447354 @default.
• W4385684857 cites W2991831637 @default.
• W4385684857 cites W3036213481 @default.
• W4385684857 cites W3119005666 @default.
• W4385684857 cites W4220892444 @default.
• W4385684857 cites W4225265689 @default.
• W4385684857 cites W4291019811 @default.
• W4385684857 cites W4304182712 @default.
• W4385684857 doi "https://doi.org/10.1007/s00428-023-03612-8" @default.
• W4385684857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37555982" @default.
• W4385684857 hasPublicationYear "2023" @default.
• W4385684857 type Work @default.
• W4385684857 citedByCount "0" @default.
• W4385684857 crossrefType "journal-article" @default.
• W4385684857 hasAuthorship W4385684857A5023565241 @default.
• W4385684857 hasAuthorship W4385684857A5034025853 @default.
• W4385684857 hasAuthorship W4385684857A5043962045 @default.
• W4385684857 hasAuthorship W4385684857A5053322701 @default.
• W4385684857 hasAuthorship W4385684857A5053906317 @default.
• W4385684857 hasAuthorship W4385684857A5056308350 @default.
• W4385684857 hasAuthorship W4385684857A5057257315 @default.
• W4385684857 hasAuthorship W4385684857A5068440444 @default.
• W4385684857 hasBestOaLocation W43856848571 @default.
• W4385684857 hasConcept C10515644 @default.
• W4385684857 hasConcept C126322002 @default.
• W4385684857 hasConcept C142724271 @default.
• W4385684857 hasConcept C143998085 @default.
• W4385684857 hasConcept C144301174 @default.
• W4385684857 hasConcept C18903297 @default.
• W4385684857 hasConcept C2776256026 @default.
• W4385684857 hasConcept C2777286243 @default.
• W4385684857 hasConcept C2777546739 @default.
• W4385684857 hasConcept C3019992690 @default.
• W4385684857 hasConcept C38180746 @default.
• W4385684857 hasConcept C50382708 @default.
• W4385684857 hasConcept C58471807 @default.
• W4385684857 hasConcept C71924100 @default.
• W4385684857 hasConcept C86803240 @default.
• W4385684857 hasConceptScore W4385684857C10515644 @default.
• W4385684857 hasConceptScore W4385684857C126322002 @default.
• W4385684857 hasConceptScore W4385684857C142724271 @default.
• W4385684857 hasConceptScore W4385684857C143998085 @default.
• W4385684857 hasConceptScore W4385684857C144301174 @default.
• W4385684857 hasConceptScore W4385684857C18903297 @default.
• W4385684857 hasConceptScore W4385684857C2776256026 @default.
• W4385684857 hasConceptScore W4385684857C2777286243 @default.
• W4385684857 hasConceptScore W4385684857C2777546739 @default.

• next