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- W4385718054 abstract "Large-scale networks of phase synchronization are considered to regulate the communication between brain regions fundamental to cognitive function, but the mapping to their structural substrates, i.e., the structure-function relationship, remains poorly understood. Biophysical Network Models (BNMs) have demonstrated the influences of local oscillatory activity and inter-regional anatomical connections in generating alpha-band (8-12 Hz) networks of phase synchronization observed with Electroencephalography (EEG) and Magnetoencephalography (MEG). Yet, the influence of inter-regional conduction delays remains unknown. In this study, we compared a BNM with standard “distance-dependent delays”, which assumes constant conduction velocity, to BNMs with delays specified by two alternative methods accounting for spatially varying conduction velocities, “isochronous delays” and “mixed delays”. We followed the Approximate Bayesian Computation (ABC) workflow, i) specifying neurophysiologically informed prior distributions of BNM parameters, ii) verifying the suitability of the prior distributions with Prior Predictive Checks, iii) fitting each of the three BNMs to alpha-band MEG resting-state data (N = 75) with Bayesian Optimisation for Likelihood-Free Inference (BOLFI), and iv) choosing between the fitted BNMs with ABC model comparison on a separate MEG dataset (N = 30). Prior Predictive Checks revealed the range of dynamics generated by each of the BNMs to encompass those seen in the MEG data, suggesting the suitability of the prior distributions. Fitting the models to MEG data yielded reliable posterior distributions of the parameters of each of the BNMs. Finally, model comparison revealed the BNM with “distance-dependent delays”, as the most probable to describe the generation of alpha-band networks of phase synchronization seen in MEG. These findings suggest that distance-dependent delays contribute significantly to the neocortical architecture of human alpha-band networks of phase synchronization. Hence, our study illuminates the role of inter-regional delays in generating the large-scale networks of phase synchronization that might subserve the communication between regions vital to cognition." @default.
- W4385718054 created "2023-08-11" @default.
- W4385718054 creator A5003277513 @default.
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- W4385718054 creator A5045356137 @default.
- W4385718054 creator A5053092854 @default.
- W4385718054 date "2023-10-01" @default.
- W4385718054 modified "2023-10-17" @default.
- W4385718054 title "The influence of inter-regional delays in generating large-scale brain networks of phase synchronization" @default.
- W4385718054 cites W1492418896 @default.
- W4385718054 cites W1574303566 @default.
- W4385718054 cites W1603307924 @default.
- W4385718054 cites W1885185971 @default.
- W4385718054 cites W1902335101 @default.
- W4385718054 cites W1905362184 @default.
- W4385718054 cites W1912168853 @default.
- W4385718054 cites W1966641148 @default.
- W4385718054 cites W1967064349 @default.
- W4385718054 cites W1967950674 @default.
- W4385718054 cites W1969204074 @default.
- W4385718054 cites W1969637629 @default.
- W4385718054 cites W1970126268 @default.
- W4385718054 cites W1971935885 @default.
- W4385718054 cites W1979330140 @default.
- W4385718054 cites W1981592426 @default.
- W4385718054 cites W1985808169 @default.
- W4385718054 cites W1995138343 @default.
- W4385718054 cites W1999174202 @default.
- W4385718054 cites W2005105933 @default.
- W4385718054 cites W2005283617 @default.
- W4385718054 cites W2005821483 @default.
- W4385718054 cites W2007581301 @default.
- W4385718054 cites W2010459589 @default.
- W4385718054 cites W2013150886 @default.
- W4385718054 cites W2016354087 @default.
- W4385718054 cites W2024729467 @default.
- W4385718054 cites W2025603247 @default.
- W4385718054 cites W2027063265 @default.
- W4385718054 cites W2028803857 @default.
- W4385718054 cites W2032616735 @default.
- W4385718054 cites W2033216467 @default.
- W4385718054 cites W2046198005 @default.
- W4385718054 cites W2047468618 @default.
- W4385718054 cites W2048419276 @default.
- W4385718054 cites W2048939758 @default.
- W4385718054 cites W2050873013 @default.
- W4385718054 cites W2056018333 @default.
- W4385718054 cites W2058779926 @default.
- W4385718054 cites W2064163434 @default.
- W4385718054 cites W2064965260 @default.
- W4385718054 cites W2064971633 @default.
- W4385718054 cites W2068414647 @default.
- W4385718054 cites W2069931166 @default.
- W4385718054 cites W2070765152 @default.
- W4385718054 cites W2072928391 @default.
- W4385718054 cites W2076618566 @default.
- W4385718054 cites W2090410452 @default.
- W4385718054 cites W2094435366 @default.
- W4385718054 cites W2095196670 @default.
- W4385718054 cites W2099604946 @default.
- W4385718054 cites W2101009588 @default.
- W4385718054 cites W2104731571 @default.
- W4385718054 cites W2105400683 @default.
- W4385718054 cites W2105848238 @default.
- W4385718054 cites W2116647777 @default.
- W4385718054 cites W2118497295 @default.
- W4385718054 cites W2124475033 @default.
- W4385718054 cites W2131215403 @default.
- W4385718054 cites W2133478841 @default.
- W4385718054 cites W2133665775 @default.
- W4385718054 cites W2135595031 @default.
- W4385718054 cites W2135908272 @default.
- W4385718054 cites W2136363447 @default.
- W4385718054 cites W2147225543 @default.
- W4385718054 cites W2147352539 @default.
- W4385718054 cites W2147916701 @default.
- W4385718054 cites W2148351310 @default.
- W4385718054 cites W2151729750 @default.
- W4385718054 cites W2157787057 @default.
- W4385718054 cites W2169596190 @default.
- W4385718054 cites W2232008374 @default.
- W4385718054 cites W2408961640 @default.
- W4385718054 cites W2463784123 @default.
- W4385718054 cites W2495207352 @default.
- W4385718054 cites W2582652687 @default.
- W4385718054 cites W2589221278 @default.
- W4385718054 cites W2590144118 @default.
- W4385718054 cites W2608079295 @default.
- W4385718054 cites W2622948156 @default.
- W4385718054 cites W2739540458 @default.
- W4385718054 cites W2763692854 @default.
- W4385718054 cites W2768920954 @default.
- W4385718054 cites W2788786700 @default.
- W4385718054 cites W2790578698 @default.