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- W4385727228 abstract "Abstract Time-varying functional connectivity (FC) methods are used to map the spatiotemporal organization of brain activity. However, their estimation can be unstable, in the sense that different runs of the inference may yield different solutions. But to draw meaningful relations to behavior, estimates must be robust and reproducible. Here, we propose two solutions using the Hidden Markov Model (HMM) as a descriptive model of time-varying FC. The first, best-ranked HMM, involves running the inference multiple times and selecting the best model based on a quantitative measure combining fitness and model complexity. The second, hierarchical clustered HMM, generates stable cluster state timeseries by applying hierarchical clustering to the state timeseries obtained from multiple runs. Experimental results on fMRI and MEG data demonstrate that these approaches substantially improve the stability of time-varying FC estimations. Overall, hierarchical clustered HMM is preferred when the inference variability is high, while the best-ranked HMM performs better otherwise." @default.
- W4385727228 created "2023-08-11" @default.
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- W4385727228 date "2023-08-10" @default.
- W4385727228 modified "2023-09-27" @default.
- W4385727228 title "Towards stability of dynamic FC estimates in neuroimaging and electrophysiology: solutions and limits" @default.
- W4385727228 doi "https://doi.org/10.1162/netn_a_00331" @default.
- W4385727228 hasPublicationYear "2023" @default.
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